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Aliases for MIR1289-1 Gene

Subcategory (RNA class) for MIR1289-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1289-1 Gene

  • MicroRNA 1289-1 2 3 5
  • Hsa-Mir-1289-1 3
  • MIRN1289-1 3

External Ids for MIR1289-1 Gene

Previous HGNC Symbols for MIR1289-1 Gene

  • MIRN1289-1

Previous GeneCards Identifiers for MIR1289-1 Gene

  • GC00U922984
  • GC20M033506
  • GC20M034041

Summaries for MIR1289-1 Gene

Entrez Gene Summary for MIR1289-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1289-1 Gene

MIR1289-1 (MicroRNA 1289-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1289-1 Gene

Genomics for MIR1289-1 Gene

Regulatory Elements for MIR1289-1 Gene

Enhancers for MIR1289-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F035479 0.6 ENCODE 11.5 -25.2 -25174 0.2 CTCF TEAD1 CEBPB REST ZNF48 RAD21 TEAD3 TGIF2 CEBPA MBD1 GDF5 CEP250 MIR1289-1 ENSG00000242507 C20orf173 NFS1 ROMO1 GDF5OS CNBD2 LOC102725201
GH20F035301 1.4 FANTOM5 Ensembl ENCODE 11 +148.1 148090 9.0 PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 UQCC1 NCOA6 GDF5 RPL36P4 MMP24-AS1 EDEM2 MMP24 MIR1289-1 CEP250 RBM12
GH20F035367 0.5 ENCODE 10.9 +84.3 84307 4.2 HLF MAX FEZF1 MNT FOS PRDM10 MAFK MYC ZNF652 UQCC1 FAM83C EIF6 FAM83C-AS1 GDF5 MIR1289-1 CEP250 MMP24-AS1 MMP24 NCOA6
GH20F035496 0.4 ENCODE 10.8 -43.5 -43529 2.0 ATF1 PKNOX1 ARNT CREB3L1 DMAP1 ZNF766 GATA2 NCOA1 CREB3 MEF2D MIR1289-1 CEP250 GDF5 LOC102725201 GC20P035518
GH20F035343 1.1 Ensembl ENCODE 10.3 +109.5 109462 1.5 ELF3 HDAC1 CBX3 TBL1XR1 ARID4B ZNF48 RAD21 YY1 GATA2 EGR2 MIR1289-1 CEP250 GDF5 FAM83C UQCC1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1289-1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1289-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000400294 -1004 2600 MLX WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for MIR1289-1 Gene

Chromosome:
20
Start:
35,453,954 bp from pter
End:
35,454,097 bp from pter
Size:
144 bases
Orientation:
Minus strand

Genomic View for MIR1289-1 Gene

Genes around MIR1289-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1289-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1289-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1289-1 Gene

Proteins for MIR1289-1 Gene

Post-translational modifications for MIR1289-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1289-1 Gene

Domains & Families for MIR1289-1 Gene

Gene Families for MIR1289-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1289-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1289-1 Gene

Function for MIR1289-1 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1289-1 Gene

Localization for MIR1289-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1289-1 Gene

Pathways & Interactions for MIR1289-1 Gene

SuperPathways for MIR1289-1 Gene

No Data Available

Interacting Proteins for MIR1289-1 Gene

Gene Ontology (GO) - Biological Process for MIR1289-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1289-1 Gene

Transcripts for MIR1289-1 Gene

mRNA/cDNA for MIR1289-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1289-1 Gene

No ASD Table

Relevant External Links for MIR1289-1 Gene

GeneLoc Exon Structure for
MIR1289-1
ECgene alternative splicing isoforms for
MIR1289-1

Expression for MIR1289-1 Gene

mRNA expression in normal human tissues for MIR1289-1 Gene

genes like me logo Genes that share expression patterns with MIR1289-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1289-1 Gene

Orthologs for MIR1289-1 Gene

Evolution for MIR1289-1 Gene

ENSEMBL:
Gene Tree for MIR1289-1 (if available)
TreeFam:
Gene Tree for MIR1289-1 (if available)

No data available for Orthologs for MIR1289-1 Gene

Paralogs for MIR1289-1 Gene

No data available for Paralogs for MIR1289-1 Gene

Variants for MIR1289-1 Gene

Sequence variations from dbSNP and Humsavar for MIR1289-1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs115545043 -- 35,455,893(+) AAGGG(C/T)CCATT intron-variant, upstream-variant-2KB
rs11698201 -- 35,453,580(+) CATCG(G/T)TTTCT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs139776822 -- 35,454,503(+) GCATG(G/T)GTCCT intron-variant, upstream-variant-2KB
rs139884309 -- 35,454,020(+) CCCGG(C/T)TTAGG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs140221048 -- 35,454,796(+) GGTGG(-/A)GCTGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1289-1 Gene

Variant ID Type Subtype PubMed ID
nsv833963 CNV gain 17160897

Relevant External Links for MIR1289-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1289-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1289-1 Gene

Disorders for MIR1289-1 Gene

Relevant External Links for MIR1289-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1289-1

No disorders were found for MIR1289-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1289-1 Gene

Publications for MIR1289-1 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1289-1 Gene

Sources for MIR1289-1 Gene

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