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Aliases for MIR1287 Gene

Subcategory (RNA class) for MIR1287 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1287 Gene

  • MicroRNA 1287 2 3 5
  • Hsa-Mir-1287 3
  • Mir-1287 3
  • MIRN1287 3

External Ids for MIR1287 Gene

Previous HGNC Symbols for MIR1287 Gene

  • MIRN1287

Previous GeneCards Identifiers for MIR1287 Gene

  • GC00U923096
  • GC10M100145
  • GC10M100154

Summaries for MIR1287 Gene

Entrez Gene Summary for MIR1287 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1287 Gene

MIR1287 (MicroRNA 1287) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1287 Gene

Genomics for MIR1287 Gene

Regulatory Elements for MIR1287 Gene

Enhancers for MIR1287 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G098373 0.9 Ensembl ENCODE 13.1 +20.8 20770 2.1 PKNOX1 MAFG ZIC2 FOXA1 ZNF316 FOS NFE2 MAFK EMSY NFE2L2 PYROXD2 LOXL4 MIR1287 LOC105378449
GH10G098390 1 Ensembl ENCODE 0.7 +3.6 3606 1.5 HDAC1 USF1 BACH1 MAX CEBPG EGR1 NFYB EED TRIM24 NR2F1 PYROXD2 LOXL4 MIR1287 LOC105378449
GH10G098360 1.5 FANTOM5 Ensembl ENCODE 0.3 +33.9 33915 1.6 HDAC1 PKNOX1 ATF1 ARNT TCF12 EGR1 FOS ETV6 CREM NFIC PYROXD2 LOXL4 LOC105378449 MIR1287
GH10G098403 1.1 Ensembl ENCODE 0.4 -9.3 -9266 2.7 HDGF PKNOX1 FOXA2 KLF17 YY1 RELB ETV6 IKZF2 CREM CEBPB PYROXD2 LOXL4 HPS1 GC10P098406 MIR1287
GH10G098394 0.6 ENCODE 0.7 +0.7 665 1.1 CTCF MAZ MAX REST RAD21 NR2F2 SMARCA4 POLR2A ZNF341 SMC3 PYROXD2 LOXL4 MIR1287 LOC105378449
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1287 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1287 Gene

Chromosome:
10
Start:
98,395,218 bp from pter
End:
98,395,307 bp from pter
Size:
90 bases
Orientation:
Minus strand

Genomic View for MIR1287 Gene

Genes around MIR1287 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1287 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1287 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1287 Gene

ORGUL Member Location for MIR1287 Gene

ORGUL Member Location for MIR1287 gene

Proteins for MIR1287 Gene

Post-translational modifications for MIR1287 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1287 Gene

Domains & Families for MIR1287 Gene

Gene Families for MIR1287 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1287: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1287 Gene

Function for MIR1287 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1287 Gene

Localization for MIR1287 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1287 Gene

Pathways & Interactions for MIR1287 Gene

SuperPathways for MIR1287 Gene

No Data Available

Interacting Proteins for MIR1287 Gene

Gene Ontology (GO) - Biological Process for MIR1287 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1287 Gene

Transcripts for MIR1287 Gene

mRNA/cDNA for MIR1287 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1287 Gene

No ASD Table

Relevant External Links for MIR1287 Gene

GeneLoc Exon Structure for
MIR1287
ECgene alternative splicing isoforms for
MIR1287

Expression for MIR1287 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1287 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1287 Gene:

MIR1287
genes like me logo Genes that share expression patterns with MIR1287: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1287 Gene

Orthologs for MIR1287 Gene

Evolution for MIR1287 Gene

ENSEMBL:
Gene Tree for MIR1287 (if available)
TreeFam:
Gene Tree for MIR1287 (if available)

No data available for Orthologs for MIR1287 Gene

Paralogs for MIR1287 Gene

No data available for Paralogs for MIR1287 Gene

Variants for MIR1287 Gene

Sequence variations from dbSNP and Humsavar for MIR1287 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000700258 -- 98,395,982(+) TAGTG(C/T)CTGAC intron-variant, upstream-variant-2KB
rs1001164840 -- 98,395,654(+) ACATC(G/T)CTGAA intron-variant, upstream-variant-2KB
rs1003405904 -- 98,394,740(+) AGTGT(A/G)TACCA intron-variant, downstream-variant-500B, utr-variant-5-prime
rs1004929612 -- 98,395,015(+) ACCGC(A/T)GTTCT intron-variant, nc-transcript-variant, downstream-variant-500B, utr-variant-5-prime
rs1005276854 -- 98,396,550(+) ATGAG(A/C)CTTCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1287 Gene

Variant ID Type Subtype PubMed ID
nsv515723 CNV loss 19592680

Relevant External Links for MIR1287 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1287

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1287 Gene

Disorders for MIR1287 Gene

Relevant External Links for MIR1287

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1287

No disorders were found for MIR1287 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1287 Gene

Publications for MIR1287 Gene

  1. Diagnostic and Prognostic Value of miR-1287 in Colorectal Cancer. (PMID: 27251300) Fateh A. … Ravanbakhsh R. (J Gastrointest Cancer 2016) 3 64
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  3. Identification of predictive biomarkers for early diagnosis of larynx carcinoma based on microRNA expression data. (PMID: 24238754) Wang Y. … Xiao B. (Cancer Genet 2013) 3 64
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  5. A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. (PMID: 21931564) Nicholson G. … Holmes C.C. (PLoS Genet. 2011) 3 64

Products for MIR1287 Gene

Sources for MIR1287 Gene

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