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Aliases for MIR1286 Gene

Subcategory (RNA class) for MIR1286 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1286 Gene

  • MicroRNA 1286 2 3 5
  • Hsa-Mir-1286 3
  • Mir-1286 3
  • MIRN1286 3

External Ids for MIR1286 Gene

Previous HGNC Symbols for MIR1286 Gene

  • MIRN1286

Previous GeneCards Identifiers for MIR1286 Gene

  • GC00U923144
  • GC22M018617
  • GC22M020236

Summaries for MIR1286 Gene

Entrez Gene Summary for MIR1286 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1286 Gene

MIR1286 (MicroRNA 1286) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1286 Gene

Genomics for MIR1286 Gene

Regulatory Elements for MIR1286 Gene

Enhancers for MIR1286 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F020242 1.5 FANTOM5 Ensembl ENCODE 0.8 +4.2 4177 5.9 HDGF ATF1 PKNOX1 GLIS2 KLF7 KLF13 ZNF263 SP3 JUNB REST LOC100420177 THAP7 THAP7-AS1 DGCR8 RTN4R TRMT2A MIR1286 LOC105372864
GH22F020249 0.8 Ensembl ENCODE 0.8 -0.8 -789 1.4 GLIS2 SMARCA4 FOXP2 HMGN3 KLF8 MIR1286 RTN4R
GH22F020270 1.1 FANTOM5 Ensembl 0.3 -21.4 -21394 1.2 HDAC1 PTRF RAD21 GLIS2 ZNF766 SCRT2 ZMIZ1 SMARCA5 ZBTB2 MIER1 RTN4R MIR1286
GH22F020267 0.9 ENCODE 0.3 -19.2 -19183 1.2 CBX3 TBL1XR1 KLF17 RAD21 GLIS2 ZNF143 KLF7 CREM KLF13 EGR2 LOC100420177 THAP7 THAP7-AS1 DGCR8 RTN4R MIR1286
GH22F020271 0.8 Ensembl 0.3 -22.5 -22507 0.6 BCOR CTCF ESRRA RAD21 GLIS2 ZMIZ1 KLF13 SMARCA5 RNF2 NRF1 RTN4R MIR1286
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1286 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1286 Gene

Chromosome:
22
Start:
20,249,134 bp from pter
End:
20,249,211 bp from pter
Size:
78 bases
Orientation:
Minus strand

Genomic View for MIR1286 Gene

Genes around MIR1286 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1286 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1286 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1286 Gene

ORGUL Member Location for MIR1286 Gene

ORGUL Member Location for MIR1286 gene

Proteins for MIR1286 Gene

Post-translational modifications for MIR1286 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1286 Gene

Domains & Families for MIR1286 Gene

Gene Families for MIR1286 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1286: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1286 Gene

Function for MIR1286 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1286 Gene

Localization for MIR1286 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1286 Gene

Pathways & Interactions for MIR1286 Gene

SuperPathways for MIR1286 Gene

No Data Available

Interacting Proteins for MIR1286 Gene

Gene Ontology (GO) - Biological Process for MIR1286 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1286 Gene

Transcripts for MIR1286 Gene

mRNA/cDNA for MIR1286 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1286 Gene

No ASD Table

Relevant External Links for MIR1286 Gene

GeneLoc Exon Structure for
MIR1286
ECgene alternative splicing isoforms for
MIR1286

Expression for MIR1286 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1286 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1286 Gene:

MIR1286
genes like me logo Genes that share expression patterns with MIR1286: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1286 Gene

Orthologs for MIR1286 Gene

Evolution for MIR1286 Gene

ENSEMBL:
Gene Tree for MIR1286 (if available)
TreeFam:
Gene Tree for MIR1286 (if available)

No data available for Orthologs for MIR1286 Gene

Paralogs for MIR1286 Gene

No data available for Paralogs for MIR1286 Gene

Variants for MIR1286 Gene

Sequence variations from dbSNP and Humsavar for MIR1286 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs111745046 -- 20,249,307(+) TCCCA(A/T)GCCCA intron-variant, upstream-variant-2KB
rs112245493 -- 20,248,989(+) GGGCC(C/T)CTGGA intron-variant, downstream-variant-500B
rs112445097 -- 20,249,384(+) GCTAG(C/T)ATCCA intron-variant, upstream-variant-2KB
rs113516329 -- 20,251,061(+) CTCCA(C/T)GCCAG intron-variant, upstream-variant-2KB
rs116647430 -- 20,250,262(+) CTGCT(A/G)CTTCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1286 Gene

Variant ID Type Subtype PubMed ID
nsv953027 CNV deletion 24416366
nsv834134 CNV loss 17160897
nsv828939 CNV loss 20364138
nsv828938 CNV gain 20364138
nsv471183 CNV loss 18288195
esv3893435 CNV gain 25118596
esv3893434 CNV gain 25118596
esv2758825 CNV loss 17122850
dgv7983n54 CNV gain 21841781
dgv726n67 CNV gain 20364138
dgv4482n100 CNV gain 25217958
dgv4481n100 CNV gain 25217958
dgv4480n100 CNV gain 25217958

Relevant External Links for MIR1286 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1286

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1286 Gene

Disorders for MIR1286 Gene

Relevant External Links for MIR1286

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1286

No disorders were found for MIR1286 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1286 Gene

Publications for MIR1286 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1286 Gene

Sources for MIR1286 Gene

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