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Aliases for MIR1284 Gene

Subcategory (RNA class) for MIR1284 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1284 Gene

  • MicroRNA 1284 2 3 5
  • Hsa-Mir-1284 3
  • Mir-1284 3
  • MIRN1284 3

External Ids for MIR1284 Gene

Previous HGNC Symbols for MIR1284 Gene

  • MIRN1284

Previous GeneCards Identifiers for MIR1284 Gene

  • GC00U922939
  • GC03M071674

Summaries for MIR1284 Gene

Entrez Gene Summary for MIR1284 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1284 Gene

MIR1284 (MicroRNA 1284) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1284 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1284 Gene

Genomics for MIR1284 Gene

GeneHancer (GH) Regulatory Elements for MIR1284 Gene

Promoters and enhancers for MIR1284 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I071541 Promoter/Enhancer 2 VISTA EPDnew Ensembl ENCODE dbSUPER 550.8 -0.6 -561 2.5 ATF1 PKNOX1 TCF12 ZNF121 ATF7 RUNX3 YY2 REST ZNF592 MEF2D FOXP1 MIR1284 FOXP1-IT1 ENSG00000274387 GC03P071510
GH03I071575 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.1 -39.0 -39006 11.4 PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 ZNF143 LOC105377155 FOXP1 FOXP1-IT1 MIR1284 EIF4E3 GC03P071583 ENSG00000270562
GH03I071438 Enhancer 2.1 VISTA UCNEbase FANTOM5 Ensembl ENCODE dbSUPER 11.2 +92.8 92826 20.9 PKNOX1 FOXA2 ZBTB40 RAD21 RCOR1 FOS IKZF2 RUNX3 CEBPB ELF1 MIR1284 EIF4E3 FOXP1-IT1 GC03P071415 GC03P071510 FOXP1
GH03I071508 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.8 +30.9 30943 4.6 PKNOX1 FEZF1 ZNF2 RAD21 FOS ATF7 ZNF654 CEBPB REST ZEB2 GC03P071510 MIR1284 EIF4E3 FOXP1
GH03I071502 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +38.0 38003 2.8 CLOCK ATF1 SIN3A BRCA1 RFX5 FOS CEBPB REST SP1 MAFF MIR1284 FOXP1-IT1 EIF4E3 GC03P071510 FOXP1 GC03P071415
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1284 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1284 Gene

Genomic Locations for MIR1284 Gene
chr3:71,541,970-71,542,089
(GRCh38/hg38)
Size:
120 bases
Orientation:
Minus strand
chr3:71,591,121-71,591,240
(GRCh37/hg19)

Genomic View for MIR1284 Gene

Genes around MIR1284 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1284 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1284 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1284 Gene

ORGUL Member Location for MIR1284 Gene

ORGUL Member Location for MIR1284 gene

Proteins for MIR1284 Gene

Post-translational modifications for MIR1284 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1284 Gene

Domains & Families for MIR1284 Gene

Gene Families for MIR1284 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1284: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1284 Gene

Function for MIR1284 Gene

Phenotypes From GWAS Catalog for MIR1284 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1284 Gene

Localization for MIR1284 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1284 Gene

Pathways & Interactions for MIR1284 Gene

SuperPathways for MIR1284 Gene

No Data Available

Interacting Proteins for MIR1284 Gene

Gene Ontology (GO) - Biological Process for MIR1284 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1284 Gene

Drugs & Compounds for MIR1284 Gene

No Compound Related Data Available

Transcripts for MIR1284 Gene

mRNA/cDNA for MIR1284 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1284 Gene

No ASD Table

Relevant External Links for MIR1284 Gene

GeneLoc Exon Structure for
MIR1284
ECgene alternative splicing isoforms for
MIR1284

Expression for MIR1284 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1284 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1284 Gene:

MIR1284
genes like me logo Genes that share expression patterns with MIR1284: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1284 Gene

Orthologs for MIR1284 Gene

Evolution for MIR1284 Gene

ENSEMBL:
Gene Tree for MIR1284 (if available)
TreeFam:
Gene Tree for MIR1284 (if available)

No data available for Orthologs for MIR1284 Gene

Paralogs for MIR1284 Gene

No data available for Paralogs for MIR1284 Gene

Variants for MIR1284 Gene

Sequence variations from dbSNP and Humsavar for MIR1284 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1001088403 -- 71,541,655(-) C/A/T downstream_transcript_variant
rs1003337747 -- 71,541,604(-) G/C downstream_transcript_variant
rs1003723144 -- 71,542,709(-) G/A upstream_transcript_variant
rs1005212672 -- 71,542,649(-) G/A upstream_transcript_variant
rs1005221143 -- 71,542,400(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1284 Gene

Variant ID Type Subtype PubMed ID
nsv999942 CNV gain 25217958

Additional Variant Information for MIR1284 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1284

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1284 Gene

Disorders for MIR1284 Gene

Additional Disease Information for MIR1284

No disorders were found for MIR1284 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1284 Gene

Publications for MIR1284 Gene

  1. MiR-1284 modulates multidrug resistance of gastric cancer cells by targeting EIF4A1. (PMID: 26936591) Cao W … Xiao Q (Oncology reports 2016) 3 58
  2. MicroRNA-1284 Inhibits Cell Viability and Induces Apoptosis of Ovarian Cancer Cell Line OVCAR3. (PMID: 28281963) Pan C … Yu W (Oncology research 2016) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1284 Gene

Sources for MIR1284 Gene

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