Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1277 Gene

Subcategory (RNA class) for MIR1277 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1277 Gene

  • MicroRNA 1277 2 3 5
  • Hsa-Mir-1277 3
  • MIRN1277 3

External Ids for MIR1277 Gene

Previous HGNC Symbols for MIR1277 Gene

  • MIRN1277

Previous GeneCards Identifiers for MIR1277 Gene

  • GC00U922870
  • GC0XP117405
  • GC0XP117520

Summaries for MIR1277 Gene

Entrez Gene Summary for MIR1277 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1277 Gene

MIR1277 (MicroRNA 1277) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1277 Gene

Genomics for MIR1277 Gene

Regulatory Elements for MIR1277 Gene

Enhancers for MIR1277 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF118352 1.3 FANTOM5 Ensembl ENCODE 13.6 -31.9 -31893 3.8 TAL1 JUN BMI1 RELA ZNF664 SCRT2 NR2F6 CREM TCF7L2 SCRT1 MIR1277 WDR44 DOCK11
GH0XF118344 1.1 ENCODE 12 -39.6 -39600 4.4 ATF1 PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 GLI4 DMAP1 BRCA1 ZNF2 HNRNPA1P28 NUDT19P1 MIR1277 WDR44
GH0XF118329 0.7 ENCODE 12 -57.1 -57132 0.5 SMARCE1 RNF2 MTA2 TAL1 DPF2 ARID1B HDAC2 KLF16 NCOR1 SMARCA4 MIR1277 WDR44 PIR62368
GH0XF118350 0.5 ENCODE 13.1 -35.5 -35482 0.2 SRF IKZF1 PRDM1 SPI1 MIR1277 WDR44
GH0XF118360 0.4 Ensembl 13.8 -25.6 -25594 0.8 KDM1A MIR1277 WDR44
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1277 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1277 Gene

Chromosome:
X
Start:
118,386,394 bp from pter
End:
118,386,471 bp from pter
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR1277 Gene

Genes around MIR1277 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1277 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1277 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1277 Gene

Proteins for MIR1277 Gene

Post-translational modifications for MIR1277 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1277 Gene

Domains & Families for MIR1277 Gene

Gene Families for MIR1277 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1277: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1277 Gene

Function for MIR1277 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1277 Gene

Localization for MIR1277 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1277 Gene

Pathways & Interactions for MIR1277 Gene

SuperPathways for MIR1277 Gene

No Data Available

Interacting Proteins for MIR1277 Gene

Gene Ontology (GO) - Biological Process for MIR1277 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1277 Gene

Transcripts for MIR1277 Gene

mRNA/cDNA for MIR1277 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1277 Gene

No ASD Table

Relevant External Links for MIR1277 Gene

GeneLoc Exon Structure for
MIR1277
ECgene alternative splicing isoforms for
MIR1277

Expression for MIR1277 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1277 Gene:

MIR1277
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1277 Gene

Orthologs for MIR1277 Gene

Evolution for MIR1277 Gene

ENSEMBL:
Gene Tree for MIR1277 (if available)
TreeFam:
Gene Tree for MIR1277 (if available)

No data available for Orthologs for MIR1277 Gene

Paralogs for MIR1277 Gene

No data available for Paralogs for MIR1277 Gene

Variants for MIR1277 Gene

Sequence variations from dbSNP and Humsavar for MIR1277 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs12864003 -- 118,385,619(+) TACCT(A/G)TGTAA intron-variant, upstream-variant-2KB
rs139654957 -- 118,385,225(+) ACTAT(G/T)CACAA intron-variant, upstream-variant-2KB
rs143930602 -- 118,386,225(+) GTGCA(C/G)AAAGA intron-variant, upstream-variant-2KB
rs144411459 -- 118,385,333(+) AAAGA(A/G)CGAGA intron-variant, upstream-variant-2KB
rs181857925 -- 118,385,013(+) CATTT(A/G)TTTTG intron-variant, upstream-variant-2KB

Relevant External Links for MIR1277 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1277

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1277 Gene

Disorders for MIR1277 Gene

Relevant External Links for MIR1277

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1277

No disorders were found for MIR1277 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1277 Gene

Publications for MIR1277 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1277 Gene

Sources for MIR1277 Gene

Content
Loading form....