Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1275 Gene

Subcategory (RNA class) for MIR1275 Gene


Quality Score for this RNA gene is


Aliases for MIR1275 Gene

  • MicroRNA 1275 2 3 5
  • Hsa-Mir-1275 3
  • Mir-1275 3
  • MIRN1275 3

External Ids for MIR1275 Gene

Previous HGNC Symbols for MIR1275 Gene

  • MIRN1275

Previous GeneCards Identifiers for MIR1275 Gene

  • GC00U922833
  • GC06M034076
  • GC06M033967
  • GC06M034527
  • GC06M035546
  • GC06M036225
  • GC06M036634
  • GC06M036988
  • GC06M037339

Summaries for MIR1275 Gene

Entrez Gene Summary for MIR1275 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1275 Gene

MIR1275 (MicroRNA 1275) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1275 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1275 Gene

Genomics for MIR1275 Gene

Regulatory Elements for MIR1275 Gene

Enhancers for MIR1275 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H034072 0.9 dbSUPER 10.9 -74.6 -74560 4 ZNF473 ZNF493 YBX1 PLRG1 ZNF23 ZNF416 ZNF207 EGR2 ZNF202 ZNF488 TAF11 LEMD2 HCG25 RING1 DAXX VPS52 RXRB WDR46 RGL2 RPS10
GH06H033956 0.8 dbSUPER 11.9 +40.4 40432 6.9 CTCF NFIB ZNF792 TAL1 ZNF223 ZIC2 RAD21 ZFHX2 LCORL ZBTB48 LEMD2 BRD2 TAF11 VPS52 MIR1275 RGL2 MLN DAXX RXRB HCG25
GH06H033922 0.7 dbSUPER 12 +72.8 72810 9.9 PKNOX1 ZNF140 EBF1 BATF ZIC2 NFYB SCRT2 FOS IKZF2 SCRT1 LEMD2 RING1 HCG25 VPS52 BRD2 TAF11 MIR1275 RXRB MLN IP6K3
GH06H033842 0.8 dbSUPER 10.4 +155.2 155244 5.1 BCOR HDAC1 PKNOX1 KLF1 PTBP1 ZFP64 ZMYM3 ZIC2 CC2D1A ZFHX2 MLN LEMD2 GRM4 MIR1275 IP6K3 HMGA1 PIRC26 LOC105375025
GH06H034094 0.7 FANTOM5 dbSUPER 11.2 -94.6 -94634 0.2 GLIS2 GLIS1 ZIC2 GRM4 MIR1275 MLN LEMD2 IP6K3 PIR53321
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1275 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1275 Gene

Genomic Locations for MIR1275 Gene
80 bases
Minus strand

Genomic View for MIR1275 Gene

Genes around MIR1275 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1275 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1275 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1275 Gene

Proteins for MIR1275 Gene

Post-translational modifications for MIR1275 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1275 Gene

Domains & Families for MIR1275 Gene

Gene Families for MIR1275 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1275: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1275 Gene

Function for MIR1275 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1275 Gene

Localization for MIR1275 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1275 Gene

Pathways & Interactions for MIR1275 Gene

SuperPathways for MIR1275 Gene

No Data Available

Interacting Proteins for MIR1275 Gene

Gene Ontology (GO) - Biological Process for MIR1275 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1275 Gene

Drugs & Compounds for MIR1275 Gene

No Compound Related Data Available

Transcripts for MIR1275 Gene

mRNA/cDNA for MIR1275 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1275 Gene

No ASD Table

Relevant External Links for MIR1275 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1275 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1275 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1275 Gene:

genes like me logo Genes that share expression patterns with MIR1275: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1275 Gene

Orthologs for MIR1275 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1275 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1275 34
  • 100 (a)
Species where no ortholog for MIR1275 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1275 Gene

Gene Tree for MIR1275 (if available)
Gene Tree for MIR1275 (if available)

Paralogs for MIR1275 Gene

No data available for Paralogs for MIR1275 Gene

Variants for MIR1275 Gene

Sequence variations from dbSNP and Humsavar for MIR1275 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1001087099 -- 34,000,564(+) GGCGA(A/C)GTCCA upstream-variant-2KB
rs1001956527 -- 34,000,248(+) GTTCA(A/G)AGAGC upstream-variant-2KB
rs1004897971 -- 34,001,182(+) GGTGG(C/T)ACACA upstream-variant-2KB
rs1004932442 -- 34,000,906(+) AGGAG(A/C)AGCTG upstream-variant-2KB
rs1007383608 -- 34,001,724(+) AGGAC(C/T)GAGAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1275 Gene

Variant ID Type Subtype PubMed ID
nsv602861 CNV loss 21841781
nsv602843 CNV gain 21841781
esv3608650 CNV gain 21293372
esv3608649 CNV loss 21293372
esv3608630 CNV gain 21293372
esv2661199 CNV deletion 23128226
esv23448 CNV loss 19812545

Relevant External Links for MIR1275 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1275 Gene

Disorders for MIR1275 Gene

Relevant External Links for MIR1275

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1275 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1275 Gene

Publications for MIR1275 Gene

  1. miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma. (PMID: 26160756) Fawzy IO … Abdelaziz AI (FEBS letters 2015) 3 60
  2. Genome-wide association analysis of age-at-onset in Alzheimer's disease. (PMID: 22005931) Kamboh MI … Lopez OL (Molecular psychiatry 2012) 3 60
  3. Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells. (PMID: 22736761) Katsushima K … Kondo Y (The Journal of biological chemistry 2012) 3 60
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  5. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 60

Products for MIR1275 Gene

Sources for MIR1275 Gene

Loading form....