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Aliases for MIR1275 Gene

Subcategory (RNA class) for MIR1275 Gene


Quality Score for this RNA gene is


Aliases for MIR1275 Gene

  • MicroRNA 1275 2 3
  • Hsa-Mir-1275 3
  • MIRN1275 3

External Ids for MIR1275 Gene

Previous HGNC Symbols for MIR1275 Gene

  • MIRN1275

Previous GeneCards Identifiers for MIR1275 Gene

  • GC00U922833
  • GC06M034076
  • GC06M033967

Summaries for MIR1275 Gene

Entrez Gene Summary for MIR1275 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1275 Gene

MIR1275 (MicroRNA 1275) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1275 Gene

Genomics for MIR1275 Gene

Genomic Location for MIR1275 Gene

33,999,972 bp from pter
34,000,051 bp from pter
80 bases
Minus strand

Genomic View for MIR1275 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1275 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1275 Gene

No data available for Regulatory Elements for MIR1275 Gene

Proteins for MIR1275 Gene

Post-translational modifications for MIR1275 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1275 Gene

Domains for MIR1275 Gene

Gene Families for MIR1275 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1275: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1275 Gene

Function for MIR1275 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1275 Gene

Localization for MIR1275 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1275 Gene

Pathways for MIR1275 Gene

SuperPathways for MIR1275 Gene

No Data Available

Interacting Proteins for MIR1275 Gene

Gene Ontology (GO) - Biological Process for MIR1275 Gene


No data available for Pathways by source for MIR1275 Gene

Transcripts for MIR1275 Gene

mRNA/cDNA for MIR1275 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1275 Gene

No ASD Table

Relevant External Links for MIR1275 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1275 Gene

mRNA expression in normal human tissues for MIR1275 Gene

genes like me logo Genes that share expressions with MIR1275: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR1275 Gene

Orthologs for MIR1275 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1275 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1275 36
  • 100 (a)
Species with no ortholog for MIR1275:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1275 Gene

Gene Tree for MIR1275 (if available)
Gene Tree for MIR1275 (if available)

Paralogs for MIR1275 Gene

No data available for Paralogs for MIR1275 Gene

Variants for MIR1275 Gene

Sequence variations from dbSNP and Humsavar for MIR1275 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs2495995 -- 34,000,194(+) GGGGA(A/G)GGGGC upstream-variant-2KB
rs6457753 -- 34,001,148(+) CTACA(A/G)AAAAT upstream-variant-2KB
rs6905035 -- 34,000,351(+) AGCAC(C/T)TTCCT upstream-variant-2KB
rs6925960 -- 34,000,638(+) CCAGA(A/G)CAATA upstream-variant-2KB
rs6926184 -- 34,000,909(+) AGAAG(C/T)TGCAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1275 Gene

Variant ID Type Subtype PubMed ID
dgv6829n71 CNV Loss 21882294
esv23448 CNV Loss 19812545
esv2661199 CNV Deletion 23128226

Relevant External Links for MIR1275 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR1275 Gene

Disorders for MIR1275 Gene

No disorders were found for MIR1275 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR1275 Gene

Publications for MIR1275 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. Genome-wide association analysis of age-at-onset in Alzheimer's disease. (PMID: 22005931) Kamboh M.I. … Lopez O.L. (Mol. Psychiatry 2012) 3
  4. Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells. (PMID: 22736761) Katsushima K. … Kondo Y. (J. Biol. Chem. 2012) 3

Products for MIR1275 Gene

Sources for MIR1275 Gene

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