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Aliases for MIR1273C Gene

Subcategory (RNA class) for MIR1273C Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1273C Gene

  • MicroRNA 1273c 2 3 5
  • Hsa-Mir-1273c 3

External Ids for MIR1273C Gene

Previous GeneCards Identifiers for MIR1273C Gene

  • GC06U902043
  • GC06P155174

Summaries for MIR1273C Gene

Entrez Gene Summary for MIR1273C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1273C Gene

MIR1273C (MicroRNA 1273c) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1273C Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1273C Gene

Genomics for MIR1273C Gene

GeneHancer (GH) Regulatory Elements for MIR1273C Gene

Promoters and enhancers for MIR1273C Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I154852 Enhancer 0.9 ENCODE 550.8 -0.5 -528 0.1 FOXA2 FEZF1 BRCA1 ZNF2 ZNF213 ZNF302 ATF7 SP3 REST TSHZ1 MIR1273C SCAF8 ENSG00000238963 ENSG00000218757 TIAM2 GC06P154648
GH06I154863 Enhancer 0.7 ENCODE 0.4 +10.5 10545 1.2 SOX5 TFAP4 SAP130 TEAD1 HLF ZSCAN4 ARID4B CEBPG TEAD3 SLC30A9 ENSG00000238963 SCAF8 MIR1273C TIAM2
GH06I154874 Enhancer 0.7 ENCODE 0.3 +21.9 21893 1.1 SCRT1 FOXA2 TEAD1 CEBPG PPARG ZNF843 TEAD3 CTBP1 PRDM6 BCL6B ENSG00000238963 MIR1273C TIAM2
GH06I154891 Enhancer 0.5 ENCODE 0.3 +38.8 38817 1.5 ELF3 FOXA2 ZFP64 SCRT2 HNF4A HOMEZ PRDM1 ENSG00000238963 MIR1273C TIAM2
GH06I154860 Enhancer 0.3 FANTOM5 0.4 +7.0 6992 0.3 ENSG00000238963 TIAM2 MIR1273C GC06P154648
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1273C on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1273C Gene

Genomic Locations for MIR1273C Gene
chr6:154,853,360-154,853,436
(GRCh38/hg38)
Size:
77 bases
Orientation:
Plus strand
chr6:155,174,494-155,174,570
(GRCh37/hg19)

Genomic View for MIR1273C Gene

Genes around MIR1273C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1273C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1273C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1273C Gene

Proteins for MIR1273C Gene

Post-translational modifications for MIR1273C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1273C Gene

Domains & Families for MIR1273C Gene

Gene Families for MIR1273C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1273C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1273C Gene

Function for MIR1273C Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1273C Gene

Localization for MIR1273C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1273C Gene

Pathways & Interactions for MIR1273C Gene

SuperPathways for MIR1273C Gene

No Data Available

Interacting Proteins for MIR1273C Gene

Gene Ontology (GO) - Biological Process for MIR1273C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1273C Gene

Drugs & Compounds for MIR1273C Gene

No Compound Related Data Available

Transcripts for MIR1273C Gene

mRNA/cDNA for MIR1273C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1273C Gene

No ASD Table

Relevant External Links for MIR1273C Gene

GeneLoc Exon Structure for
MIR1273C
ECgene alternative splicing isoforms for
MIR1273C

Expression for MIR1273C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1273C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1273C Gene:

MIR1273C
genes like me logo Genes that share expression patterns with MIR1273C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1273C Gene

Orthologs for MIR1273C Gene

Evolution for MIR1273C Gene

ENSEMBL:
Gene Tree for MIR1273C (if available)
TreeFam:
Gene Tree for MIR1273C (if available)

No data available for Orthologs for MIR1273C Gene

Paralogs for MIR1273C Gene

No data available for Paralogs for MIR1273C Gene

Variants for MIR1273C Gene

Sequence variations from dbSNP and Humsavar for MIR1273C Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000509681 -- 154,853,276(+) G/A upstream_transcript_variant
rs1000577094 -- 154,851,976(+) T/C upstream_transcript_variant
rs1001047966 -- 154,853,024(+) C/G upstream_transcript_variant
rs1004307267 -- 154,852,267(+) A/C upstream_transcript_variant
rs1004675705 -- 154,853,919(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1273C Gene

Variant ID Type Subtype PubMed ID
esv3611331 CNV loss 21293372
nsv5551 CNV deletion 18451855

Additional Variant Information for MIR1273C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1273C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1273C Gene

Disorders for MIR1273C Gene

Additional Disease Information for MIR1273C

No disorders were found for MIR1273C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1273C Gene

Publications for MIR1273C Gene

  1. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 58
  2. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1273C Gene

Sources for MIR1273C Gene

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