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Aliases for MIR1273A Gene

Subcategory (RNA class) for MIR1273A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1273A Gene

  • MicroRNA 1273a 2 3 5
  • MicroRNA 1273 2 3
  • Hsa-Mir-1273a 3
  • Hsa-Mir-1273 3
  • MIRN1273 3
  • MIR1273 3

External Ids for MIR1273A Gene

Previous HGNC Symbols for MIR1273A Gene

  • MIRN1273
  • MIR1273

Previous GeneCards Identifiers for MIR1273A Gene

  • GC08M101036

Summaries for MIR1273A Gene

Entrez Gene Summary for MIR1273A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1273A Gene

MIR1273A (MicroRNA 1273a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1273A Gene

Genomics for MIR1273A Gene

Regulatory Elements for MIR1273A Gene

Enhancers for MIR1273A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F099903 0.6 ENCODE 10.1 +119.1 119097 2.2 PKNOX1 SIN3A ZBTB40 RAD21 FOS EGR2 GATAD2B MBD2 SMARCA4 ZBTB33 RGS22 MIR1273A VPS13B COX6C PIR32500
GH08F100025 0.2 ENCODE 0.8 -1.9 -1930 0.6 GLIS1 MAFK MIR1273A PIR62937
GH08F100019 0.7 ENCODE 0.8 +4.7 4657 0.2 CTCF ZNF654 HCFC1 CEBPB RAD21 ZNF766 GATA3 ATF3 SMC3 CUX1 MIR1273A ENSG00000212414
GH08F100026 0.7 ENCODE 0.8 -2.3 -2314 0.0 MAFK MIR1273A PIR62937
GH08F100027 0.5 ENCODE 0.8 -1.2 -1164 0.2 HDAC1 ATF1 ARNT CREB3L1 ZFP64 INSM2 CHAMP1 ZNF766 GATA2 SCRT2 MIR1273A PIR62937
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1273A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1273A Gene

Chromosome:
8
Start:
100,023,982 bp from pter
End:
100,024,084 bp from pter
Size:
103 bases
Orientation:
Minus strand

Genomic View for MIR1273A Gene

Genes around MIR1273A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1273A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1273A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1273A Gene

Proteins for MIR1273A Gene

Post-translational modifications for MIR1273A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1273A Gene

Domains & Families for MIR1273A Gene

Gene Families for MIR1273A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1273A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1273A Gene

Function for MIR1273A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1273A Gene

Localization for MIR1273A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1273A Gene

Pathways & Interactions for MIR1273A Gene

SuperPathways for MIR1273A Gene

No Data Available

Interacting Proteins for MIR1273A Gene

Gene Ontology (GO) - Biological Process for MIR1273A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1273A Gene

Transcripts for MIR1273A Gene

mRNA/cDNA for MIR1273A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1273A Gene

No ASD Table

Relevant External Links for MIR1273A Gene

GeneLoc Exon Structure for
MIR1273A
ECgene alternative splicing isoforms for
MIR1273A

Expression for MIR1273A Gene

mRNA expression in normal human tissues for MIR1273A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1273A Gene:

MIR1273A
genes like me logo Genes that share expression patterns with MIR1273A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1273A Gene

Orthologs for MIR1273A Gene

Evolution for MIR1273A Gene

ENSEMBL:
Gene Tree for MIR1273A (if available)
TreeFam:
Gene Tree for MIR1273A (if available)

No data available for Orthologs for MIR1273A Gene

Paralogs for MIR1273A Gene

No data available for Paralogs for MIR1273A Gene

Variants for MIR1273A Gene

Sequence variations from dbSNP and Humsavar for MIR1273A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs114904569 -- 100,023,518(+) AGCCT(C/T)CAATT intron-variant, downstream-variant-500B
rs138639258 -- 100,025,229(+) CAACA(C/T)GAGAA intron-variant, upstream-variant-2KB
rs139915926 -- 100,024,497(+) TTATA(-/T)GGCAC intron-variant, upstream-variant-2KB, reference, frameshift-variant
rs141253009 -- 100,023,794(+) GTGAA(A/G)CCTTT intron-variant, downstream-variant-500B
rs143538665 -- 100,025,581(+) GAGAA(C/T)TTAGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1273A Gene

Variant ID Type Subtype PubMed ID
nsv1030482 CNV loss 25217958

Relevant External Links for MIR1273A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1273A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1273A Gene

Disorders for MIR1273A Gene

Relevant External Links for MIR1273A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1273A

No disorders were found for MIR1273A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1273A Gene

Publications for MIR1273A Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1273A Gene

Sources for MIR1273A Gene

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