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Aliases for MIR1271 Gene

Subcategory (RNA class) for MIR1271 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR1271 Gene

  • MicroRNA 1271 2 3 5
  • Hsa-Mir-1271 3
  • MIRN1271 3

External Ids for MIR1271 Gene

ORGUL Members for MIR1271 Gene

Previous HGNC Symbols for MIR1271 Gene

  • MIRN1271

Previous GeneCards Identifiers for MIR1271 Gene

  • GC00U922886
  • GC05P175729
  • GC05P175794

Summaries for MIR1271 Gene

Entrez Gene Summary for MIR1271 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1271 Gene

MIR1271 (MicroRNA 1271) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1271 Gene

Genomics for MIR1271 Gene

Regulatory Elements for MIR1271 Gene

Enhancers for MIR1271 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G176410 1.6 Ensembl ENCODE dbSUPER 10.9 +47.0 46971 8.8 PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF143 ZNF207 ENSG00000251414 FAF2 HIGD2A ARL10 NOP16 ENSG00000250909 MIR1271 KIAA1191 CDHR2 RN7SL684P
GH05G176552 1.3 Ensembl ENCODE dbSUPER 10.3 +185.9 185863 3.5 BCOR SIN3A ZMYM3 BMI1 ZIC2 ZKSCAN1 GLIS2 POLR2A FOSL2 FOS FAF2 ARL10 MIR1271 KIAA1191 UNC5A CDHR2 GC05P176557 GC05M176548
GH05G176423 1.2 ENCODE dbSUPER 10.8 +58.1 58094 5.6 FOXA2 ATF1 MLX ARID4B SIN3A ZNF48 YY1 GATA2 MXD4 ZHX2 FAF2 CDHR2 RN7SL684P MIR1271 KIAA1191 ARL10 GPRIN1 ENSG00000251414 HIGD2A CLTB
GH05G176596 1 Ensembl ENCODE 9.6 +229.2 229240 2.3 CTCF SUZ12 ZFP64 ZNF140 RBBP5 RAD21 ZNF101 ZNF697 POLR2A ZBTB11 EIF4E1B SNCB TSPAN17 RN7SL684P CDHR2 FAF2 MIR1271 ARL10 KIAA1191 PIR54069
GH05G176340 0.8 ENCODE 11.6 -26.0 -25984 2.6 PKNOX1 FOXA2 NFIB RARA TCF12 ZNF121 GATA2 ZEB2 NFIC PRDM6 KIAA1191 ARL10 MIR1271 SIMC1 FAM153B ENSG00000250909 BRCC3P1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1271 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1271 Gene

Chromosome:
5
Start:
176,367,946 bp from pter
End:
176,368,031 bp from pter
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR1271 Gene

Genes around MIR1271 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1271 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1271 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1271 Gene

Proteins for MIR1271 Gene

Post-translational modifications for MIR1271 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1271 Gene

Domains & Families for MIR1271 Gene

Gene Families for MIR1271 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1271: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1271 Gene

Function for MIR1271 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1271 Gene

Localization for MIR1271 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1271 Gene

Pathways & Interactions for MIR1271 Gene

SuperPathways for MIR1271 Gene

No Data Available

Interacting Proteins for MIR1271 Gene

Gene Ontology (GO) - Biological Process for MIR1271 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1271 Gene

Transcripts for MIR1271 Gene

mRNA/cDNA for MIR1271 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1271 Gene

No ASD Table

Relevant External Links for MIR1271 Gene

GeneLoc Exon Structure for
MIR1271
ECgene alternative splicing isoforms for
MIR1271

Expression for MIR1271 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1271 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1271 Gene:

MIR1271
genes like me logo Genes that share expression patterns with MIR1271: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1271 Gene

Orthologs for MIR1271 Gene

Evolution for MIR1271 Gene

ENSEMBL:
Gene Tree for MIR1271 (if available)
TreeFam:
Gene Tree for MIR1271 (if available)

No data available for Orthologs for MIR1271 Gene

Paralogs for MIR1271 Gene

No data available for Paralogs for MIR1271 Gene

Variants for MIR1271 Gene

Sequence variations from dbSNP and Humsavar for MIR1271 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1003354377 -- 176,366,108(+) GGGGG(G/T)GGGGA intron-variant, upstream-variant-2KB
rs1003813163 -- 176,368,136(+) GGACT(A/G)TGCAG intron-variant, downstream-variant-500B
rs1004401373 -- 176,366,458(+) ATGGC(A/G)CAGGC upstream-variant-2KB, reference, missense
rs1004805819 -- 176,365,983(+) CTCCA(C/T)GCCAT intron-variant, upstream-variant-2KB
rs1004836896 -- 176,366,208(+) CCAAG(A/G)GTTTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1271 Gene

Variant ID Type Subtype PubMed ID
nsv1023853 CNV gain 25217958
nsv462549 CNV gain 19166990
nsv600341 CNV gain 21841781

Relevant External Links for MIR1271 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1271

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1271 Gene

Disorders for MIR1271 Gene

Relevant External Links for MIR1271

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1271

No disorders were found for MIR1271 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1271 Gene

Publications for MIR1271 Gene

  1. Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes. (PMID: 28260088) Chen S. … Mei Q. (Oncol. Rep. 2017) 3 64
  2. MicroRNA-1271 inhibits proliferation and promotes apoptosis of multiple myeloma cells through inhibiting smoothened-mediated Hedgehog signaling pathway. (PMID: 27959416) Xu Z. … Hao D. (Oncol. Rep. 2017) 3 64
  3. miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells. (PMID: 26940738) Liu H. … Yu T. (Biochem. Biophys. Res. Commun. 2016) 3 64
  4. miR-1271 promotes non-small-cell lung cancer cell proliferation and invasion via targeting HOXA5. (PMID: 25686496) Wang Y. … Jiang L. (Biochem. Biophys. Res. Commun. 2015) 3 64
  5. MiR-1271 Inhibits Cell Proliferation, Invasion and EMT in Gastric Cancer by Targeting FOXQ1. (PMID: 26159618) Xiang X.J. … Xiong J.P. (Cell. Physiol. Biochem. 2015) 3 64

Products for MIR1271 Gene

Sources for MIR1271 Gene

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