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Aliases for MIR1269B Gene

Subcategory (RNA class) for MIR1269B Gene


Quality Score for this RNA gene is


Aliases for MIR1269B Gene

  • MicroRNA 1269b 2 3 5
  • Hsa-Mir-1269b 3

External Ids for MIR1269B Gene

Previous GeneCards Identifiers for MIR1269B Gene

  • GC17U901638

Summaries for MIR1269B Gene

Entrez Gene Summary for MIR1269B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1269B Gene

MIR1269B (MicroRNA 1269b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1269B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1269B Gene

Genomics for MIR1269B Gene

GeneHancer (GH) Regulatory Elements for MIR1269B Gene

Promoters and enhancers for MIR1269B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I012893 Enhancer 0.2 FANTOM5 0.3 +23.9 23879 0.1 ARHGAP44 MIR1269B GC17M012817
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1269B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1269B Gene

Genomic Locations for MIR1269B Gene
75 bases
Minus strand

Genomic View for MIR1269B Gene

Genes around MIR1269B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1269B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1269B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1269B Gene

Proteins for MIR1269B Gene

Post-translational modifications for MIR1269B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1269B Gene

Domains & Families for MIR1269B Gene

Gene Families for MIR1269B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1269B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1269B Gene

Function for MIR1269B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1269B Gene

Localization for MIR1269B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1269B Gene

Pathways & Interactions for MIR1269B Gene

SuperPathways for MIR1269B Gene

No Data Available

Interacting Proteins for MIR1269B Gene

Gene Ontology (GO) - Biological Process for MIR1269B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1269B Gene

Drugs & Compounds for MIR1269B Gene

No Compound Related Data Available

Transcripts for MIR1269B Gene

mRNA/cDNA for MIR1269B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1269B Gene

No ASD Table

Relevant External Links for MIR1269B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1269B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1269B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1269B Gene

Orthologs for MIR1269B Gene

Evolution for MIR1269B Gene

Gene Tree for MIR1269B (if available)
Gene Tree for MIR1269B (if available)

No data available for Orthologs for MIR1269B Gene

Paralogs for MIR1269B Gene

No data available for Paralogs for MIR1269B Gene

Variants for MIR1269B Gene

Sequence variations from dbSNP and Humsavar for MIR1269B Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000076501 -- 12,919,096(-) T/G upstream_transcript_variant
rs1000680721 -- 12,917,869(-) G/A upstream_transcript_variant
rs1000730758 -- 12,916,907(-) C/G/T downstream_transcript_variant
rs1002123536 -- 12,917,514(-) C/G upstream_transcript_variant
rs1002435915 -- 12,916,996(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1269B Gene

Variant ID Type Subtype PubMed ID
esv3639982 CNV loss 21293372
nsv1060977 CNV gain 25217958
nsv833372 CNV loss 17160897

Additional Variant Information for MIR1269B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1269B Gene

Disorders for MIR1269B Gene

Additional Disease Information for MIR1269B

No disorders were found for MIR1269B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1269B Gene

Publications for MIR1269B Gene

  1. HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells. (PMID: 27349221) Kong XX … Tang H (Journal of translational medicine 2016) 3 58
  2. Genetic variants in microRNA-146a (C>G) and microRNA-1269b (G>C) are associated with the decreased risk of oral premalignant lesions, oral cancer, and pharyngeal cancer. (PMID: 27525378) Chen HC … Ger LP (Archives of oral biology 2016) 3 58
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1269B Gene

Sources for MIR1269B Gene

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