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Aliases for MIR1269A Gene

Subcategory (RNA class) for MIR1269A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1269A Gene

  • MicroRNA 1269a 2 3 5
  • MicroRNA 1269 2 3
  • Hsa-Mir-1269a 3
  • Hsa-Mir-1269 3
  • MIRN1269 3
  • MIR1269 3

External Ids for MIR1269A Gene

Previous HGNC Symbols for MIR1269A Gene

  • MIRN1269
  • MIR1269

Previous GeneCards Identifiers for MIR1269A Gene

  • GC04P067143

Summaries for MIR1269A Gene

Entrez Gene Summary for MIR1269A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1269A Gene

MIR1269A (MicroRNA 1269a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1269A Gene

Genomics for MIR1269A Gene

Genomic Location for MIR1269A Gene

Chromosome:
4
Start:
66,276,824 bp from pter
End:
66,276,928 bp from pter
Size:
105 bases
Orientation:
Plus strand

Genomic View for MIR1269A Gene

Genes around MIR1269A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1269A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1269A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1269A Gene

No data available for Regulatory Elements for MIR1269A Gene

Proteins for MIR1269A Gene

Post-translational modifications for MIR1269A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1269A Gene

Domains & Families for MIR1269A Gene

Gene Families for MIR1269A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1269A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1269A Gene

Function for MIR1269A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1269A Gene

Localization for MIR1269A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1269A Gene

Pathways & Interactions for MIR1269A Gene

SuperPathways for MIR1269A Gene

No Data Available

Interacting Proteins for MIR1269A Gene

Gene Ontology (GO) - Biological Process for MIR1269A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1269A Gene

Drugs & Compounds for MIR1269A Gene

No Compound Related Data Available

Transcripts for MIR1269A Gene

mRNA/cDNA for MIR1269A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1269A Gene

No ASD Table

Relevant External Links for MIR1269A Gene

GeneLoc Exon Structure for
MIR1269A
ECgene alternative splicing isoforms for
MIR1269A

Expression for MIR1269A Gene

mRNA expression in normal human tissues for MIR1269A Gene

genes like me logo Genes that share expression patterns with MIR1269A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1269A Gene

Orthologs for MIR1269A Gene

Evolution for MIR1269A Gene

ENSEMBL:
Gene Tree for MIR1269A (if available)
TreeFam:
Gene Tree for MIR1269A (if available)

No data available for Orthologs for MIR1269A Gene

Paralogs for MIR1269A Gene

No data available for Paralogs for MIR1269A Gene

Variants for MIR1269A Gene

Sequence variations from dbSNP and Humsavar for MIR1269A Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1397753 -- 66,275,297(-) AAGCT(C/G)CCCAG upstream-variant-2KB
rs1397754 -- 66,275,152(-) TGAAA(C/T)CACAC upstream-variant-2KB
rs1397755 -- 66,275,116(-) TTTAG(C/T)GCTAA upstream-variant-2KB
rs977772 -- 66,276,283(-) CGGGG(C/T)GGGGG upstream-variant-2KB
rs977773 -- 66,276,071(-) TAACA(C/T)AGGTA upstream-variant-2KB

Relevant External Links for MIR1269A Gene

HapMap Linkage Disequilibrium report
MIR1269A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1269A Gene

Disorders for MIR1269A Gene

Relevant External Links for MIR1269A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1269A

No disorders were found for MIR1269A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1269A Gene

Publications for MIR1269A Gene

  1. MicroRNA-1269 promotes proliferation in human hepatocellular carcinoma via downregulation of FOXO1. (PMID: 25472505) Yang X.W. … Xue P. (BMC Cancer 2014) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR1269A Gene

Sources for MIR1269A Gene

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