Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1268B Gene

Subcategory (RNA class) for MIR1268B Gene


Quality Score for this RNA gene is


Aliases for MIR1268B Gene

  • MicroRNA 1268b 2 3 5
  • Hsa-Mir-1268b 3

External Ids for MIR1268B Gene

Previous GeneCards Identifiers for MIR1268B Gene

  • GC17U901632
  • GC17P078073

Summaries for MIR1268B Gene

Entrez Gene Summary for MIR1268B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1268B Gene

MIR1268B (MicroRNA 1268b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1268B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1268B Gene

Genomics for MIR1268B Gene

Regulatory Elements for MIR1268B Gene

Enhancers for MIR1268B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H080082 1 Ensembl ENCODE 0.4 -15.9 -15947 1.1 CTCF ZFP64 ARID4B RAD21 TEAD3 HIC1 PATZ1 SMC3 ZNF143 PRDM10 EIF4A3 GAA CARD14 MIR1268B GC17P080040
GH17H080068 1.2 Ensembl ENCODE 0.3 -28.6 -28611 3.8 PKNOX1 FOXA2 ZFP64 ARID4B DMAP1 YY1 ZNF121 GATA2 FOS ATF7 EIF4A3 GAA CCDC40 TBC1D16 CBX2 GC17P080040 MIR1268B
GH17H080064 1.1 Ensembl ENCODE 0.3 -34.4 -34353 0.8 ARID4B DMAP1 NFXL1 RAD21 THRB GLIS2 FOS ATF7 THAP11 CEBPB CCDC40 CARD14 EIF4A3 TBC1D16 GC17P080040 MIR1268B
GH17H080092 0.4 Ensembl 0.4 -6.1 -6124 1.4 ZNF362 GAA EIF4A3 CARD14 ENSG00000262580 MIR1268B GC17P080040
GH17H080063 0.5 ENCODE 0.3 -34.9 -34851 0.1 SKIL ZGPAT ZNF792 DMAP1 GAA GC17P080040 MIR1268B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1268B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1268B Gene

Genomic Locations for MIR1268B Gene
50 bases
Plus strand

Genomic View for MIR1268B Gene

Genes around MIR1268B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1268B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1268B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1268B Gene

Proteins for MIR1268B Gene

Post-translational modifications for MIR1268B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1268B Gene

Domains & Families for MIR1268B Gene

Gene Families for MIR1268B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1268B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1268B Gene

Function for MIR1268B Gene

Phenotypes From GWAS Catalog for MIR1268B Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1268B Gene

Localization for MIR1268B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1268B Gene

Pathways & Interactions for MIR1268B Gene

SuperPathways for MIR1268B Gene

No Data Available

Interacting Proteins for MIR1268B Gene

Gene Ontology (GO) - Biological Process for MIR1268B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1268B Gene

Drugs & Compounds for MIR1268B Gene

No Compound Related Data Available

Transcripts for MIR1268B Gene

mRNA/cDNA for MIR1268B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1268B Gene

No ASD Table

Relevant External Links for MIR1268B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1268B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1268B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1268B Gene

Orthologs for MIR1268B Gene

Evolution for MIR1268B Gene

Gene Tree for MIR1268B (if available)
Gene Tree for MIR1268B (if available)

No data available for Orthologs for MIR1268B Gene

Paralogs for MIR1268B Gene

No data available for Paralogs for MIR1268B Gene

Variants for MIR1268B Gene

Sequence variations from dbSNP and Humsavar for MIR1268B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs863224519 Pathogenic 80,097,320(+) TAGAG(A/T)AGCAG nc-transcript-variant, upstream-variant-2KB, reference, stop-gained
rs79588289 Likely benign 80,097,250(+) GCCAC(C/T)GATGA nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs886038640 Likely benign 80,097,332(+) AAAAG(C/G)TGTCG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs117307093 Uncertain significance 80,097,269(+) AAACC(A/G)TCCTG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs12952612 Benign 80,097,253(+) ACCGA(A/C/T)GAGTG nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for MIR1268B Gene

Variant ID Type Subtype PubMed ID
nsv833561 CNV loss 17160897
nsv469591 CNV loss 16826518
nsv1066606 CNV gain 25217958
esv3641363 CNV gain 21293372
esv3641362 CNV loss 21293372

Relevant External Links for MIR1268B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1268B Gene

Disorders for MIR1268B Gene

Relevant External Links for MIR1268B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1268B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1268B Gene

Publications for MIR1268B Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1268B Gene

Sources for MIR1268B Gene

Loading form....