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Aliases for MIR1268A Gene

Subcategory (RNA class) for MIR1268A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1268A Gene

  • MicroRNA 1268a 2 3 5
  • MicroRNA 1268 2 3
  • Hsa-Mir-1268a 3
  • Hsa-Mir-1268 3
  • MIRN1268 3
  • MIR1268 3

External Ids for MIR1268A Gene

Previous HGNC Symbols for MIR1268A Gene

  • MIRN1268
  • MIR1268

Previous GeneCards Identifiers for MIR1268A Gene

  • GC15M022514

Summaries for MIR1268A Gene

Entrez Gene Summary for MIR1268A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1268A Gene

MIR1268A (MicroRNA 1268a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1268A Gene

Genomics for MIR1268A Gene

Regulatory Elements for MIR1268A Gene

Enhancers for MIR1268A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F022220 0.8 Ensembl ENCODE 0.8 +3.9 3898 1.3 CTCF TEAD1 SMC3 TEAD2 RAD21 TEAD3 MIR1268A PIR41171
GH15F022223 0.7 ENCODE 0.8 +2.0 2025 0.2 GTF2F1 CTCF ZNF654 REST RAD21 JUND POLR3A ZNF143 SMC3 ZHX1 LOC646214 MIR1268A PIR41171
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1268A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1268A Gene

Chromosome:
15
Start:
22,225,278 bp from pter
End:
22,225,329 bp from pter
Size:
52 bases
Orientation:
Minus strand

Genomic View for MIR1268A Gene

Genes around MIR1268A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1268A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1268A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1268A Gene

Proteins for MIR1268A Gene

Post-translational modifications for MIR1268A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1268A Gene

Domains & Families for MIR1268A Gene

Gene Families for MIR1268A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1268A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1268A Gene

Function for MIR1268A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1268A Gene

Localization for MIR1268A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1268A Gene

Pathways & Interactions for MIR1268A Gene

SuperPathways for MIR1268A Gene

No Data Available

Interacting Proteins for MIR1268A Gene

Gene Ontology (GO) - Biological Process for MIR1268A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1268A Gene

Transcripts for MIR1268A Gene

mRNA/cDNA for MIR1268A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1268A Gene

No ASD Table

Relevant External Links for MIR1268A Gene

GeneLoc Exon Structure for
MIR1268A
ECgene alternative splicing isoforms for
MIR1268A

Expression for MIR1268A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1268A Gene:

MIR1268A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1268A Gene

Orthologs for MIR1268A Gene

Evolution for MIR1268A Gene

ENSEMBL:
Gene Tree for MIR1268A (if available)
TreeFam:
Gene Tree for MIR1268A (if available)

No data available for Orthologs for MIR1268A Gene

Paralogs for MIR1268A Gene

No data available for Paralogs for MIR1268A Gene

Variants for MIR1268A Gene

Sequence variations from dbSNP and Humsavar for MIR1268A Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1001443 -- 22,227,028(+) AGCCA(C/T)GACAT intron-variant, upstream-variant-2KB
rs1001444 -- 22,227,090(+) AGGGA(C/T)GGATC intron-variant, upstream-variant-2KB
rs10528547 -- 22,225,355(+) TTTTT(-/TTTTTTTT)GTAGA intron-variant, upstream-variant-2KB
rs111291154 -- 22,225,433(+) CCCAC(A/C)TCAGC intron-variant, upstream-variant-2KB
rs111428232 -- 22,225,363(+) TTTTT(A/G/T)TAGAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1268A Gene

Variant ID Type Subtype PubMed ID
dgv2401n100 CNV gain 25217958
dgv2402n100 CNV loss 25217958
dgv2491n100 CNV gain 25217958
dgv2492n100 CNV gain 25217958
dgv3e224 CNV gain+loss 25118596
dgv4144n106 CNV deletion 24896259
dgv4162n54 CNV loss 21841781
dgv4222n54 CNV gain 21841781
dgv4223n54 CNV gain+loss 21841781
dgv4224n54 CNV loss 21841781
dgv422n67 CNV gain 20364138
dgv4260n54 CNV gain+loss 21841781
nsv820577 CNV deletion 20802225
nsv820602 CNV duplication 20802225
nsv821425 CNV duplication 20802225
nsv821678 CNV loss 15273396
nsv825097 CNV loss 20364138
nsv825099 CNV loss 20364138
nsv825100 CNV loss 20364138
nsv825103 CNV loss 20364138
nsv827237 CNV gain 20364138
nsv827239 CNV gain 20364138
nsv831728 CNV loss 17160897
nsv832918 CNV gain+loss 17160897
nsv832919 CNV gain+loss 17160897
nsv832920 CNV loss 17160897
nsv832941 CNV gain+loss 17160897
nsv833709 CNV loss 17160897
nsv9179 CNV gain+loss 18304495
nsv9208 CNV gain+loss 18304495
nsv9209 CNV loss 18304495
nsv9210 CNV gain 18304495
nsv951774 CNV deletion 24416366
nsv952580 CNV deletion 24416366
nsv952581 CNV deletion 24416366
nsv952582 CNV deletion 24416366
nsv952583 CNV duplication 24416366
nsv952585 CNV deletion 24416366
nsv952586 CNV duplication 24416366
nsv952587 CNV duplication 24416366
nsv952588 CNV duplication 24416366
nsv956099 CNV deletion 24416366
nsv956125 CNV deletion 24416366
nsv957095 CNV deletion 24416366
dgv2399n100 CNV loss 25217958
dgv2397n100 CNV gain 25217958
dgv2396n100 CNV gain 25217958
dgv2394n100 CNV gain+loss 25217958
dgv2393n100 CNV gain 25217958
dgv2391n100 CNV loss 25217958
dgv2387n100 CNV gain 25217958
dgv2374n100 CNV loss 25217958
dgv2373n100 CNV gain+loss 25217958
dgv2372n100 CNV gain 25217958
dgv2368n100 CNV loss 25217958
dgv2365n100 CNV gain+loss 25217958
dgv2364n100 CNV gain 25217958
dgv2333n100 CNV loss 25217958
dgv2332n100 CNV gain 25217958
dgv2327n100 CNV gain 25217958
dgv2325n100 CNV gain+loss 25217958
dgv2301n100 CNV loss 25217958
dgv2290n100 CNV gain+loss 25217958
dgv2284n100 CNV gain 25217958
dgv2283n100 CNV gain 25217958
dgv2282n100 CNV gain 25217958
dgv2238n100 CNV gain 25217958
dgv2214n100 CNV gain 25217958
dgv2193n100 CNV gain+loss 25217958
dgv2192n100 CNV loss 25217958
dgv2191n100 CNV gain+loss 25217958
dgv2183n100 CNV loss 25217958
dgv2181n100 CNV gain 25217958
dgv2179n100 CNV gain 25217958
dgv2175n100 CNV gain 25217958
dgv1n1 OTHER inversion 15895083
dgv1379e199 CNV deletion 23128226
dgv1378e199 CNV deletion 23128226
dgv1371e59 CNV duplication 20981092
dgv12881n54 CNV gain 21841781
dgv1236n67 CNV loss 20364138
dgv11n14 CNV gain 18776910
dgv1163n106 CNV duplication 24896259
dgv10n14 CNV loss 18776910
dgv100e55 CNV loss 17911159
nsv819960 CNV gain 19587683
nsv819298 CNV loss 19587683
nsv7260 OTHER inversion 18451855
nsv615390 CNV gain 21841781
nsv615388 CNV loss 21841781
nsv615387 CNV gain+loss 21841781
nsv615385 CNV loss 21841781
nsv615384 CNV gain 21841781
nsv578420 CNV loss 21841781
nsv568674 CNV loss 21841781
nsv568673 CNV loss 21841781
nsv568667 CNV loss 21841781
nsv568666 CNV loss 21841781
nsv568662 CNV gain 21841781
nsv568136 CNV gain 21841781
nsv568129 CNV loss 21841781
nsv567312 CNV gain 21841781
nsv526979 CNV gain 19592680
nsv514767 CNV gain+loss 21397061
nsv512119 CNV loss 21212237
nsv511041 OTHER inversion 20534489
nsv510653 CNV deletion 20534489
nsv509562 CNV insertion 20534489
nsv469883 CNV gain 16826518
nsv442688 CNV gain 18776908
nsv433431 CNV gain 18776910
nsv433289 CNV loss 18776910
nsv428299 CNV loss 18775914
nsv428296 CNV gain+loss 18775914
nsv416781 CNV deletion 16902084
nsv415888 CNV insertion 16902084
nsv2391 CNV insertion 18451855
nsv1153772 CNV duplication 26484159
nsv1152123 CNV duplication 26484159
nsv1151134 CNV duplication 26484159
nsv1150825 CNV duplication 26484159
nsv1150724 CNV deletion 26484159
nsv1150469 CNV duplication 26484159
nsv1149868 CNV duplication 26484159
nsv1149300 CNV duplication 26484159
nsv1148573 CNV duplication 26484159
nsv1148560 OTHER inversion 26484159
nsv1148230 CNV duplication 26484159
nsv1148060 CNV duplication 26484159
nsv1147314 CNV duplication 26484159
nsv1145960 CNV duplication 26484159
nsv1144855 CNV deletion 24896259
nsv1141259 CNV duplication 24896259
nsv1139624 CNV duplication 24896259
nsv1139623 CNV duplication 24896259
nsv1139622 CNV duplication 24896259
nsv1136268 CNV deletion 24896259
nsv1132411 CNV duplication 24896259
nsv1132410 CNV duplication 24896259
nsv1132226 CNV deletion 24896259
nsv1128723 CNV duplication 24896259
nsv1128722 CNV duplication 24896259
nsv1128520 CNV deletion 24896259
nsv1126506 CNV deletion 24896259
nsv1124704 CNV duplication 24896259
nsv1121892 CNV deletion 24896259
nsv1118553 CNV duplication 24896259
nsv1118369 CNV deletion 24896259
nsv1112739 CNV deletion 24896259
nsv1078380 CNV duplication 25765185
nsv1077806 CNV duplication 25765185
nsv1077805 CNV duplication 25765185
nsv1077804 CNV duplication 25765185
nsv1077799 CNV duplication 25765185
nsv1076408 CNV duplication 25765185
nsv1075678 CNV deletion 25765185
nsv1075485 CNV duplication 25765185
nsv1075484 CNV duplication 25765185
nsv1072304 CNV deletion 25765185
nsv1071892 CNV deletion 25765185
nsv1071891 CNV deletion 25765185
nsv1070685 CNV deletion 25765185
nsv1061420 CNV gain 25217958
nsv1052131 CNV gain 25217958
nsv1051715 CNV gain+loss 25217958
nsv1051081 CNV gain 25217958
nsv1044853 CNV gain 25217958
nsv1043475 CNV gain 25217958
nsv1040079 CNV gain 25217958
nsv1036457 CNV loss 25217958
esv3892612 CNV gain 25118596
esv3892609 CNV gain 25118596
esv3892607 CNV gain 25118596
esv3643453 CNV loss 21293372
esv3643452 CNV loss 21293372
esv3621813 CNV loss 21293372
esv3621812 CNV loss 21293372
esv3621811 CNV loss 21293372
esv3621810 CNV loss 21293372
esv3621809 CNV loss 21293372
esv3621808 CNV loss 21293372
esv3621807 CNV loss 21293372
esv3584876 CNV gain 24956385
esv3584854 CNV gain 24956385
esv3555871 CNV deletion 23714750
esv3545493 CNV deletion 23714750
esv3545492 CNV deletion 23714750
esv3545491 CNV deletion 23714750
esv3545488 CNV deletion 23714750
esv3545486 CNV deletion 23714750
esv3423649 CNV insertion 20981092
esv3368017 CNV duplication 20981092
esv33051 CNV gain+loss 17666407
esv29701 CNV gain+loss 19812545
esv2760021 CNV gain+loss 17122850
esv2751492 CNV gain 17911159
esv2739075 CNV deletion 23290073
esv2739074 CNV deletion 23290073
esv2739072 CNV deletion 23290073
esv2739071 CNV deletion 23290073
esv2739070 CNV deletion 23290073
esv2677232 CNV deletion 23128226
esv2674813 CNV deletion 23128226
esv2666546 CNV deletion 23128226
esv2660941 CNV deletion 23128226
esv2660034 CNV deletion 23128226
esv26596 CNV gain+loss 19812545
esv2618000 CNV deletion 19546169
esv26019 CNV gain+loss 19812545
esv2591544 CNV loss 19546169
esv2436971 CNV deletion 19546169
esv22824 CNV gain+loss 19812545
esv2150257 CNV deletion 18987734
esv1639805 CNV deletion 17803354
esv1498928 CNV deletion 17803354
esv1113963 CNV deletion 17803354
esv1004259 OTHER inversion 20482838
esv1002903 CNV deletion 20482838
dgv99e55 CNV gain 17911159
dgv96e55 CNV loss 17911159
dgv93e55 CNV gain 17911159
dgv92e55 CNV gain 17911159
dgv725e212 CNV loss 25503493
dgv47n68 CNV loss 17160897
dgv445e214 CNV gain 21293372
dgv4410n54 CNV loss 21841781
dgv4298n54 CNV loss 21841781
dgv4297n54 CNV loss 21841781
dgv4296n54 CNV loss 21841781
dgv4294n54 CNV loss 21841781
dgv4293n54 CNV loss 21841781
dgv4292n54 CNV loss 21841781
dgv4291n54 CNV gain 21841781
dgv4290n54 CNV loss 21841781
dgv4285n54 CNV loss 21841781
dgv4277n54 CNV gain+loss 21841781
dgv4276n54 CNV gain 21841781
dgv4274n54 CNV loss 21841781
dgv4273n54 CNV loss 21841781
dgv4264n54 CNV gain 21841781
dgv4263n54 CNV loss 21841781
dgv4262n54 CNV loss 21841781
dgv4261n54 CNV gain 21841781
nsv974539 CNV duplication 23825009
nsv974540 CNV duplication 23825009
nsv974541 CNV duplication 23825009
nsv974641 CNV duplication 23825009
nsv984037 CNV duplication 23825009

Relevant External Links for MIR1268A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1268A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1268A Gene

Disorders for MIR1268A Gene

Relevant External Links for MIR1268A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1268A

No disorders were found for MIR1268A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1268A Gene

Publications for MIR1268A Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1268A Gene

Sources for MIR1268A Gene

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