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Aliases for MIR1266 Gene

Subcategory (RNA class) for MIR1266 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1266 Gene

  • MicroRNA 1266 2 3 5
  • Hsa-Mir-1266 3
  • Mir-1266 3
  • MIRN1266 3

External Ids for MIR1266 Gene

Previous HGNC Symbols for MIR1266 Gene

  • MIRN1266

Previous GeneCards Identifiers for MIR1266 Gene

  • GC00U923051
  • GC15M050357
  • GC15M052569
  • GC15M052418
  • GC15M052689
  • GC15M054263
  • GC15M054937
  • GC15M055378
  • GC15M055827

Summaries for MIR1266 Gene

Entrez Gene Summary for MIR1266 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1266 Gene

MIR1266 (MicroRNA 1266) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1266 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1266 Gene

Genomics for MIR1266 Gene

Regulatory Elements for MIR1266 Gene

Enhancers for MIR1266 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15H052231 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.7 +43.3 43348 5.2 HDGF BACH1 BATF ZNF366 POLR2A EED ATF7 ETV6 IKZF2 CREM MYO5C GNB5 MIR1266 TMOD3 FAM214A LOC105370820 GC15M056391 GC15M056876
GH15H052256 1.1 Ensembl ENCODE 10.8 +20.8 20779 0.8 ZSCAN4 ARID4B BRCA1 RAD21 RFX5 TCF12 ZNF766 ZNF143 RUNX3 DEK MIR1266 GC15M056391 GC15M056876 LOC105370820
GH15H052651 1.2 ENCODE dbSUPER 9.8 -375.7 -375682 3.5 PKNOX1 ARID4B SIN3A YY1 FOS MXD4 NFYC MEF2D SMARCA4 HMBOX1 FAM214A GNB5 MIR1266 ENSG00000259935 LOC105370821
GH15H052331 1.1 Ensembl ENCODE 10.6 -54.5 -54534 0.9 HDGF PKNOX1 SIN3A RAD21 RFX5 GATA2 ZNF143 FOS RUNX3 SMARCA5 MIR1266 GC15M056987 GC15P052429
GH15H052254 0.9 Ensembl ENCODE 10.8 +22.2 22215 1.2 FOSL1 CTCF JUND JUN FOSL2 FOS EBF1 RAD21 MIR1266 TMOD3 GC15M056876 GC15M056391 LOC105370820
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1266 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1266 Gene

Genomic Locations for MIR1266 Gene
chr15:52,277,117-52,277,200
(GRCh38/hg38)
Size:
84 bases
Orientation:
Minus strand
chr15:52,569,314-52,569,397
(GRCh37/hg19)

Genomic View for MIR1266 Gene

Genes around MIR1266 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1266 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1266 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1266 Gene

Proteins for MIR1266 Gene

Post-translational modifications for MIR1266 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1266 Gene

Domains & Families for MIR1266 Gene

Gene Families for MIR1266 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1266: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1266 Gene

Function for MIR1266 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1266 Gene

Localization for MIR1266 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1266 Gene

Pathways & Interactions for MIR1266 Gene

SuperPathways for MIR1266 Gene

No Data Available

Interacting Proteins for MIR1266 Gene

Gene Ontology (GO) - Biological Process for MIR1266 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1266 Gene

Drugs & Compounds for MIR1266 Gene

No Compound Related Data Available

Transcripts for MIR1266 Gene

mRNA/cDNA for MIR1266 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1266 Gene

No ASD Table

Relevant External Links for MIR1266 Gene

GeneLoc Exon Structure for
MIR1266
ECgene alternative splicing isoforms for
MIR1266

Expression for MIR1266 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1266 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1266 Gene:

MIR1266
genes like me logo Genes that share expression patterns with MIR1266: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1266 Gene

Orthologs for MIR1266 Gene

Evolution for MIR1266 Gene

ENSEMBL:
Gene Tree for MIR1266 (if available)
TreeFam:
Gene Tree for MIR1266 (if available)

No data available for Orthologs for MIR1266 Gene

Paralogs for MIR1266 Gene

No data available for Paralogs for MIR1266 Gene

Variants for MIR1266 Gene

Sequence variations from dbSNP and Humsavar for MIR1266 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1001168207 -- 52,277,224(+) AACAC(A/G)AGCCT intron-variant, upstream-variant-2KB
rs1002259673 -- 52,278,237(+) TGAGC(A/G)CAAAT intron-variant, upstream-variant-2KB
rs1004563070 -- 52,276,802(+) GAGAT(A/T)TTTTA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1004790637 -- 52,278,890(+) TTGTA(C/T)GCCTC upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime
rs1004933210 -- 52,279,185(+) CCCTC(A/C/G)GGCTG intron-variant, upstream-variant-2KB

Relevant External Links for MIR1266 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1266

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1266 Gene

Disorders for MIR1266 Gene

Relevant External Links for MIR1266

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1266

No disorders were found for MIR1266 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1266 Gene

Publications for MIR1266 Gene

  1. Association of miR-1266 with recurrence/metastasis potential in estrogen receptor positive breast cancer patients. (PMID: 25640367) Sevinc ED … Evrensel T (Asian Pacific journal of cancer prevention : APJCP 2015) 3 60
  2. miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase. (PMID: 24481448) Chen L … Yang SM (Cell death & disease 2014) 3 60
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 60
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  5. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 60

Products for MIR1266 Gene

Sources for MIR1266 Gene

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