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Aliases for MIR1265 Gene

Subcategory (RNA class) for MIR1265 Gene


Quality Score for this RNA gene is


Aliases for MIR1265 Gene

  • MicroRNA 1265 2 3 5
  • Hsa-Mir-1265 3
  • MIRN1265 3

External Ids for MIR1265 Gene

Previous HGNC Symbols for MIR1265 Gene

  • MIRN1265

Previous GeneCards Identifiers for MIR1265 Gene

  • GC00U922838

Summaries for MIR1265 Gene

Entrez Gene Summary for MIR1265 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1265 Gene

MIR1265 (MicroRNA 1265) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1265 Gene

Genomics for MIR1265 Gene

Regulatory Elements for MIR1265 Gene

Enhancers for MIR1265 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F014414 0.2 ENCODE 11.5 -20.6 -20609 2.8 MTA2 TRIM22 BMI1 TBX21 JUND RAD51 IKZF1 NBN MIR1265 FRMD4A ENSG00000278100
GH10F014381 1.2 Ensembl ENCODE 11.3 -54.1 -54105 2.8 BMI1 EBF1 ZIC2 RELA ZNF664 ZFHX2 EGR1 FOS EGR2 STAT1 MIR1265 MIR4293 GC10P014349
GH10F014466 0.2 ENCODE 11.2 +30.1 30094 0.9 MAFK MIR1265 FRMD4A GC10M014524
GH10F014403 1.2 FANTOM5 Ensembl ENCODE 11.1 -31.0 -31017 4.5 PKNOX1 YBX1 ZNF664 GATA3 CTBP1 SCRT2 HNF4G FOS NFE2 MAFK FRMD4A MIR1265 ENSG00000278100
GH10F014395 0.9 FANTOM5 Ensembl ENCODE 10.7 -39.5 -39538 2.7 CTCF ZNF362 BHLHE40 MAFG ZNF384 DPF2 ZBTB40 HIC1 ZNF316 JUND MIR1265 LOC105376425 ENSG00000278100
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1265 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1265 Gene

14,436,576 bp from pter
14,436,661 bp from pter
86 bases
Plus strand

Genomic View for MIR1265 Gene

Genes around MIR1265 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1265 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1265 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1265 Gene

Proteins for MIR1265 Gene

Post-translational modifications for MIR1265 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1265 Gene

Domains & Families for MIR1265 Gene

Gene Families for MIR1265 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1265: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1265 Gene

Function for MIR1265 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1265 Gene

Localization for MIR1265 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1265 Gene

Pathways & Interactions for MIR1265 Gene

SuperPathways for MIR1265 Gene

No Data Available

Interacting Proteins for MIR1265 Gene

Gene Ontology (GO) - Biological Process for MIR1265 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1265 Gene

Transcripts for MIR1265 Gene

mRNA/cDNA for MIR1265 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1265 Gene

No ASD Table

Relevant External Links for MIR1265 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1265 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1265 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1265 Gene:

genes like me logo Genes that share expression patterns with MIR1265: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1265 Gene

Orthologs for MIR1265 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1265 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1265 35
  • 97 (a)
Species where no ortholog for MIR1265 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1265 Gene

Gene Tree for MIR1265 (if available)
Gene Tree for MIR1265 (if available)

Paralogs for MIR1265 Gene

No data available for Paralogs for MIR1265 Gene

Variants for MIR1265 Gene

Sequence variations from dbSNP and Humsavar for MIR1265 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10737086 -- 14,437,020(+) TAGAC(C/T)TCAGG downstream-variant-500B
rs10796190 -- 14,436,177(+) GTTCA(A/G)ATGTT upstream-variant-2KB
rs10796191 -- 14,436,336(+) TGTCA(C/T)CCGAT upstream-variant-2KB
rs10906674 -- 14,434,632(+) CAATA(C/T)ACTGT upstream-variant-2KB
rs10906675 -- 14,436,287(+) TAAAA(A/G)CCCAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1265 Gene

Variant ID Type Subtype PubMed ID
esv34151 CNV loss 18971310
nsv528028 CNV gain 19592680

Relevant External Links for MIR1265 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1265 Gene

Disorders for MIR1265 Gene

Relevant External Links for MIR1265

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1265 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1265 Gene

Publications for MIR1265 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1265 Gene

Sources for MIR1265 Gene

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