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Aliases for MIR1265 Gene

Subcategory (RNA class) for MIR1265 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1265 Gene

  • MicroRNA 1265 2 3
  • Hsa-Mir-1265 3
  • MIRN1265 3

External Ids for MIR1265 Gene

Previous HGNC Symbols for MIR1265 Gene

  • MIRN1265

Previous GeneCards Identifiers for MIR1265 Gene

  • GC00U922838

Summaries for MIR1265 Gene

Entrez Gene Summary for MIR1265 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1265 Gene

MIR1265 (MicroRNA 1265) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1265 Gene

Genomics for MIR1265 Gene

Genomic Location for MIR1265 Gene

Start:
14,436,576 bp from pter
End:
14,436,661 bp from pter
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR1265 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1265 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1265 Gene

No data available for Regulatory Elements for MIR1265 Gene

Proteins for MIR1265 Gene

Post-translational modifications for MIR1265 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1265 Gene

Domains for MIR1265 Gene

Gene Families for MIR1265 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1265: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1265 Gene

Function for MIR1265 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1265 Gene

Localization for MIR1265 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1265 Gene

Pathways for MIR1265 Gene

SuperPathways for MIR1265 Gene

No Data Available

Interacting Proteins for MIR1265 Gene

Gene Ontology (GO) - Biological Process for MIR1265 Gene

None

No data available for Pathways by source for MIR1265 Gene

Transcripts for MIR1265 Gene

mRNA/cDNA for MIR1265 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1265 Gene

No ASD Table

Relevant External Links for MIR1265 Gene

GeneLoc Exon Structure for
MIR1265
ECgene alternative splicing isoforms for
MIR1265

Expression for MIR1265 Gene

mRNA expression in normal human tissues for MIR1265 Gene

genes like me logo Genes that share expressions with MIR1265: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR1265 Gene

Orthologs for MIR1265 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1265 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1265 36
  • 97 (a)
OneToOne
Species with no ortholog for MIR1265:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1265 Gene

ENSEMBL:
Gene Tree for MIR1265 (if available)
TreeFam:
Gene Tree for MIR1265 (if available)

Paralogs for MIR1265 Gene

No data available for Paralogs for MIR1265 Gene

Variants for MIR1265 Gene

Sequence variations from dbSNP and Humsavar for MIR1265 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1325898 -- 14,436,798(+) TTGAG(C/G)AGTTA downstream-variant-500B
rs4750518 -- 14,435,443(+) AATTG(A/G)CTATT upstream-variant-2KB
rs7098908 -- 14,435,401(+) TTCTG(A/G)AGAAA upstream-variant-2KB
rs7896998 -- 14,437,077(+) CCTCA(C/T)GTACG downstream-variant-500B
rs10737086 -- 14,437,020(+) TAGAC(C/T)TCAGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1265 Gene

Variant ID Type Subtype PubMed ID
esv34151 CNV Loss 18971310
nsv528028 CNV Gain 19592680

Relevant External Links for MIR1265 Gene

HapMap Linkage Disequilibrium report
MIR1265

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR1265 Gene

Disorders for MIR1265 Gene

No disorders were found for MIR1265 Gene.

No data available for UniProtKB/Swiss-Prot for MIR1265 Gene

Publications for MIR1265 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3

Products for MIR1265 Gene

Sources for MIR1265 Gene

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