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Aliases for MIR1260A Gene

Subcategory (RNA class) for MIR1260A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1260A Gene

  • MicroRNA 1260a 2 3 5
  • MicroRNA 1260 2 3
  • Hsa-Mir-1260a 3
  • Hsa-Mir-1260 3
  • Mir-1260a 3
  • MIRN1260 3
  • MIR1260 3

External Ids for MIR1260A Gene

Previous HGNC Symbols for MIR1260A Gene

  • MIRN1260
  • MIR1260

Previous GeneCards Identifiers for MIR1260A Gene

  • GC14P077733

Summaries for MIR1260A Gene

Entrez Gene Summary for MIR1260A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1260A Gene

MIR1260A (MicroRNA 1260a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1260A Gene

Genomics for MIR1260A Gene

Regulatory Elements for MIR1260A Gene

Enhancers for MIR1260A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G077301 1.5 Ensembl ENCODE dbSUPER 11.2 +38.9 38866 6.5 PKNOX1 FOXA2 ATF1 ARID4B SIN3A FEZF1 ZNF2 CBX5 GATA2 ZNF143 IRF2BPL GSTZ1 ALKBH1 NGB MIR1260A ZDHHC22 ENSG00000201384 TMED8 SAMD15 RPL21P10
GH14G077208 1.2 ENCODE dbSUPER 11.5 -57.3 -57326 0.2 ZFP64 ARID4B SIN3A ZNF48 SLC30A9 ZNF143 DEK SP5 MXD4 MIER2 TMED8 MIR1260A NGB TMEM63C GC14M077202 ENSG00000201384
GH14G077299 1 ENCODE dbSUPER 11.2 +34.4 34412 2.4 CTCF FOXA2 NFIB ARID4B RAD21 GATA2 SMC3 NR2F6 ZNF652 ZNF654 GSTZ1 POMT2 NGB MIR1260A ZDHHC22 ENSG00000201384 AHSA1 VIPAS39 CIPC PIR44060
GH14G077296 0.8 ENCODE dbSUPER 11.5 +30.5 30470 1.1 NFIC ZNF544 NFIB ZIC2 GSTZ1 POMT2 NGB MIR1260A ZDHHC22 ENSG00000201384 VIPAS39 AHSA1 CIPC TMEM63C
GH14G077133 0.9 ENCODE 10.1 -132.3 -132276 0.2 ELF3 MLX ARID4B SIN3A ZNF48 ZSCAN9 RARA SLC30A9 ZNF766 ZNF143 CIPC ENSG00000201384 NGB MIR1260A SAMD15 TMED8 ENSG00000269883 TMEM63C
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1260A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1260A Gene

Chromosome:
14
Start:
77,266,218 bp from pter
End:
77,266,290 bp from pter
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR1260A Gene

Genes around MIR1260A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1260A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1260A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1260A Gene

Proteins for MIR1260A Gene

Post-translational modifications for MIR1260A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1260A Gene

Domains & Families for MIR1260A Gene

Gene Families for MIR1260A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1260A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1260A Gene

Function for MIR1260A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1260A Gene

Localization for MIR1260A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1260A Gene

Pathways & Interactions for MIR1260A Gene

SuperPathways for MIR1260A Gene

No Data Available

Interacting Proteins for MIR1260A Gene

Gene Ontology (GO) - Biological Process for MIR1260A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1260A Gene

Drugs & Compounds for MIR1260A Gene

No Compound Related Data Available

Transcripts for MIR1260A Gene

mRNA/cDNA for MIR1260A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1260A Gene

No ASD Table

Relevant External Links for MIR1260A Gene

GeneLoc Exon Structure for
MIR1260A
ECgene alternative splicing isoforms for
MIR1260A

Expression for MIR1260A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1260A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1260A Gene:

MIR1260A
genes like me logo Genes that share expression patterns with MIR1260A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1260A Gene

Orthologs for MIR1260A Gene

Evolution for MIR1260A Gene

ENSEMBL:
Gene Tree for MIR1260A (if available)
TreeFam:
Gene Tree for MIR1260A (if available)

No data available for Orthologs for MIR1260A Gene

Paralogs for MIR1260A Gene

No data available for Paralogs for MIR1260A Gene

Variants for MIR1260A Gene

Sequence variations from dbSNP and Humsavar for MIR1260A Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1001417178 -- 77,265,797(+) CTGGC(C/T)GGTCC upstream-variant-2KB, utr-variant-3-prime
rs1001482008 -- 77,265,637(+) CACAG(C/T)GGGCA upstream-variant-2KB, utr-variant-3-prime
rs1002568109 -- 77,265,017(+) AGCAG(C/T)GATTC downstream-variant-500B, upstream-variant-2KB
rs1002924588 -- 77,265,357(+) CCCCT(A/C)CCTCC downstream-variant-500B, upstream-variant-2KB
rs1003559508 -- 77,264,365(+) GGTCA(A/G)AGGAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1260A Gene

Variant ID Type Subtype PubMed ID
nsv1361 CNV deletion 18451855

Relevant External Links for MIR1260A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1260A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1260A Gene

Disorders for MIR1260A Gene

Relevant External Links for MIR1260A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1260A

No disorders were found for MIR1260A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1260A Gene

Publications for MIR1260A Gene

  1. Identification and characterization of microRNAs in vascular smooth muscle cells from patients with abdominal aortic aneurysms. (PMID: 23746831) Cheuk B.L. … Cheng S.W. (J. Vasc. Surg. 2014) 3 64
  2. microRNAs in circulation are altered in response to influenza A virus infection in humans. (PMID: 24116168) Tambyah P.A. … Jeyaseelan K. (PLoS ONE 2013) 3 64
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1260A Gene

Sources for MIR1260A Gene

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