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Aliases for MIR1258 Gene

Subcategory (RNA class) for MIR1258 Gene


Quality Score for this RNA gene is


Aliases for MIR1258 Gene

  • MicroRNA 1258 2 3
  • Hsa-Mir-1258 3
  • MIRN1258 3

External Ids for MIR1258 Gene

Previous HGNC Symbols for MIR1258 Gene

  • MIRN1258

Previous GeneCards Identifiers for MIR1258 Gene

  • GC00U923048
  • GC02M180434
  • GC02M180725

Summaries for MIR1258 Gene

Entrez Gene Summary for MIR1258 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1258 Gene

MIR1258 (MicroRNA 1258) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1258 Gene

Genomics for MIR1258 Gene

Genomic Location for MIR1258 Gene

179,860,836 bp from pter
179,860,908 bp from pter
73 bases
Minus strand

Genomic View for MIR1258 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1258 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1258 Gene

No data available for Regulatory Elements for MIR1258 Gene

Proteins for MIR1258 Gene

Post-translational modifications for MIR1258 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1258 Gene

Domains for MIR1258 Gene

Gene Families for MIR1258 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1258: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1258 Gene

Function for MIR1258 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1258 Gene

Localization for MIR1258 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1258 Gene

Pathways for MIR1258 Gene

SuperPathways for MIR1258 Gene

No Data Available

Interacting Proteins for MIR1258 Gene

Gene Ontology (GO) - Biological Process for MIR1258 Gene


No data available for Pathways by source for MIR1258 Gene

Transcripts for MIR1258 Gene

mRNA/cDNA for MIR1258 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR1258

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1258 Gene

No ASD Table

Relevant External Links for MIR1258 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1258 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR1258 Gene

Orthologs for MIR1258 Gene

Evolution for MIR1258 Gene

Gene Tree for MIR1258 (if available)
Gene Tree for MIR1258 (if available)

No data available for Orthologs for MIR1258 Gene

Paralogs for MIR1258 Gene

No data available for Paralogs for MIR1258 Gene

Variants for MIR1258 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1258 Gene

Variant ID Type Subtype PubMed ID
nsv3062 CNV Insertion 18451855
dgv4376n71 CNV Gain 21882294

Relevant External Links for MIR1258 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR1258 Gene

Disorders for MIR1258 Gene

No disorders were found for MIR1258 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR1258 Gene

Publications for MIR1258 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. The expression of heparanase and microRNA-1258 in human non-small cell lung cancer. (PMID: 22488243) Liu H. … Jiang G. (Tumour Biol. 2012) 3
  4. The expression and clinical significance of microRNA-1258 and heparanase in human breast cancer. (PMID: 23415719) Tang D. … Tian L. (Clin. Biochem. 2013) 3
  5. Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258. (PMID: 24554664) Yan Q. … Lu C. (J. Virol. 2014) 3

Products for MIR1258 Gene

Sources for MIR1258 Gene

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