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Aliases for MIR1257 Gene

Subcategory (RNA class) for MIR1257 Gene


Quality Score for this RNA gene is


Aliases for MIR1257 Gene

  • MicroRNA 1257 2 3 5
  • Hsa-Mir-1257 3
  • MIRN1257 3

External Ids for MIR1257 Gene

Previous HGNC Symbols for MIR1257 Gene

  • MIRN1257

Previous GeneCards Identifiers for MIR1257 Gene

  • GC00U922880
  • GC20M059962
  • GC20M060528

Summaries for MIR1257 Gene

Entrez Gene Summary for MIR1257 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1257 Gene

MIR1257 (MicroRNA 1257) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1257 Gene

Genomics for MIR1257 Gene

Regulatory Elements for MIR1257 Gene

Enhancers for MIR1257 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR1257 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1257 Gene

61,953,546 bp from pter
61,953,662 bp from pter
117 bases
Minus strand

Genomic View for MIR1257 Gene

Genes around MIR1257 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1257 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1257 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1257 Gene

Proteins for MIR1257 Gene

Post-translational modifications for MIR1257 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1257 Gene

Domains & Families for MIR1257 Gene

Gene Families for MIR1257 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1257: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1257 Gene

Function for MIR1257 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1257 Gene

Localization for MIR1257 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1257 Gene

Pathways & Interactions for MIR1257 Gene

SuperPathways for MIR1257 Gene

No Data Available

Interacting Proteins for MIR1257 Gene

Gene Ontology (GO) - Biological Process for MIR1257 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1257 Gene

Drugs & Compounds for MIR1257 Gene

No Compound Related Data Available

Transcripts for MIR1257 Gene

mRNA/cDNA for MIR1257 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1257 Gene

No ASD Table

Relevant External Links for MIR1257 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1257 Gene

mRNA expression in normal human tissues for MIR1257 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1257 Gene

This gene is overexpressed in Ovary (x43.1) and Kidney - Cortex (x9.9).
genes like me logo Genes that share expression patterns with MIR1257: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1257 Gene

Orthologs for MIR1257 Gene

Evolution for MIR1257 Gene

Gene Tree for MIR1257 (if available)
Gene Tree for MIR1257 (if available)

No data available for Orthologs for MIR1257 Gene

Paralogs for MIR1257 Gene

No data available for Paralogs for MIR1257 Gene

Variants for MIR1257 Gene

Sequence variations from dbSNP and Humsavar for MIR1257 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1776256 -- 61,954,759(-) GCAGG(A/C)GACAA upstream-variant-2KB
rs3850812 -- 61,954,025(-) ACTCC(C/T)GACCT upstream-variant-2KB
rs6061916 -- 61,953,878(+) ATCTC(A/G)TTAAT upstream-variant-2KB
rs6061917 -- 61,954,822(+) GTGGC(A/G)CGGGG upstream-variant-2KB
rs6121494 -- 61,953,544(+) gcttc(A/G)gaggc downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1257 Gene

Variant ID Type Subtype PubMed ID
nsv913012 CNV Loss 21882294
dgv4594n71 CNV Loss 21882294
dgv1340e1 CNV Complex 17122850
nsv428378 CNV Loss 18775914
nsv913026 CNV Loss 21882294
nsv509781 CNV Insertion 20534489
dgv4596n71 CNV Loss 21882294
nsv913029 CNV Loss 21882294
nsv3439 CNV Loss 18451855

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR1257 Gene

Disorders for MIR1257 Gene

Relevant External Links for MIR1257

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1257 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1257 Gene

Publications for MIR1257 Gene

  1. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 3 67
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR1257 Gene

Sources for MIR1257 Gene