Aliases for MIR1256 Gene
Subcategory (RNA class) for MIR1256 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR1256 Gene
- HGNC: 35321
- Entrez Gene: 100302155
- Ensembl: ENSG00000221808
- miRBase: hsa-mir-1256
ORGUL Members for MIR1256 Gene
Previous HGNC Symbols for MIR1256 Gene
- MIRN1256
Previous GeneCards Identifiers for MIR1256 Gene
- GC00U923026
- GC01M021188
- GC01M021314
Summaries for MIR1256 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR1256 Gene
MIR1256 (MicroRNA 1256) is an RNA Gene, and is affiliated with the miRNA class.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1256 Gene
Genomics for MIR1256 Gene
Regulatory Elements for MIR1256 Gene
Enhancers for MIR1256 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G021020 | 1.8 | FANTOM5 Ensembl ENCODE | 12.4 | -33.7 | -33712 | 2.6 | HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 | HP1BP3 MIR1256 EIF4G3 ECE1 CDA GC01P021023 RPS15AP6 |
| GH01G021148 | 1.5 | FANTOM5 Ensembl ENCODE | 11.1 | -162.5 | -162480 | 4.6 | ZSCAN4 INSM2 KLF17 ZNF2 ZEB1 ZNF121 GATA2 ZNF366 SCRT2 FOS | EIF4G3 MIR1256 HP1BP3 HSPE1P27 GC01M021094 |
| GH01G020964 | 1.1 | Ensembl ENCODE | 12.5 | +23.5 | 23513 | 1.4 | HDAC1 FEZF1 RAD21 ZNF335 GATA2 RELB ETV6 CREM IKZF2 GATAD2B | MIR1256 EIF4G3 LOC105376829 |
| GH01G021098 | 1 | Ensembl ENCODE | 11 | -110.9 | -110870 | 1.8 | ZNF146 BACH1 CEBPG FOSL1 ZNF121 FOXM1 ZNF316 FOS TRIM24 NFE2 | EIF4G3 MIR1256 GC01M021094 HSPE1P27 |
| GH01G021028 | 0.8 | ENCODE | 12.3 | -39.7 | -39671 | 0.2 | HDAC1 PKNOX1 CHAMP1 TCF12 GATA2 NFIC SMARCA4 PBX2 IKZF1 NR2C1 | MIR1256 GC01P021023 GC01M021067 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR1256 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR1256 Gene
- Chromosome:
- 1
- Start:
- 20,988,314 bp from pter
- End:
- 20,988,432 bp from pter
- Size:
- 119 bases
- Orientation:
- Minus strand
Genomic View for MIR1256 Gene
Genes around MIR1256 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.12 by Ensembl
- 1p36.12 by Entrez Gene
- 1p36.12 by HGNC
MIR1256 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR1256 Gene
Proteins for MIR1256 Gene
Post-translational modifications for MIR1256 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR1256
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR1256
- Origene Custom Protein Services for MIR1256
- Search GeneTex for Proteins for MIR1256
No data available for DME Specific Peptides for MIR1256 Gene
Domains & Families for MIR1256 Gene
Gene Families for MIR1256 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1256 Gene
Function for MIR1256 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR1256
-
- Search ViGene Biosciences for MIR1256
CRISPR Products
- Browse CRISPR knockouts for MIR1256
miRNA Products
- Search ViGene Biosciences for MIR1256
-
Origene geneexpression products in human, mouse, rat for MIR1256
- Browse OriGene miRNA Products For MIR1256
Inhibitory RNA Products
- Search ViGene Biosciences for MIR1256
Clone Products
- GenScript: Custom all cDNA clones Services for MIR1256
- VectorBuilder custom plasmid, inducible vectors for MIR1256
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR1256
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1256 Gene
Localization for MIR1256 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1256 Gene
Transcripts for MIR1256 Gene
mRNA/cDNA for MIR1256 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR1256
miRNA Products
- Search ViGene Biosciences for MIR1256
-
Origene geneexpression products in human, mouse, rat for MIR1256
- Browse OriGene miRNA Products For MIR1256
Inhibitory RNA Products
- Search ViGene Biosciences for MIR1256
Clone Products
- GenScript: Custom all cDNA clones Services for MIR1256
- VectorBuilder custom plasmid, inducible vectors for MIR1256
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR1256
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for MIR1256 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR1256 Gene:
MIR1256Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1256 Gene
Orthologs for MIR1256 Gene
No data available for Orthologs for MIR1256 Gene
Paralogs for MIR1256 Gene
No data available for Paralogs for MIR1256 Gene
Variants for MIR1256 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1001415012 | -- | 20,987,863(+) | AGGAA(C/G)GCATG | intron-variant, downstream-variant-500B | |
| rs1003229067 | -- | 20,989,831(+) | TTTGC(A/G)TAAAA | intron-variant, upstream-variant-2KB | |
| rs1003497619 | -- | 20,989,540(+) | TAACA(A/G)GAGCA | intron-variant, upstream-variant-2KB | |
| rs1004406125 | -- | 20,990,265(+) | AATCC(C/T)CAGCA | intron-variant, upstream-variant-2KB | |
| rs1004503335 | -- | 20,988,119(+) | AGGTA(A/C)GAAAG | intron-variant, downstream-variant-500B |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1009855 | CNV | loss | 25217958 |
| nsv1012238 | CNV | loss | 25217958 |
Relevant External Links for MIR1256 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR1256
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1256 Gene
Disorders for MIR1256 Gene
Relevant External Links for MIR1256
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR1256
No disorders were found for MIR1256 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1256 Gene
Publications for MIR1256 Gene
- Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma. (PMID: 23361059) Takeshita N. … Matsubara H. (Br. J. Cancer 2013) 3 64
- Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR1256 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR1256
- Origene Custom Protein Services for MIR1256
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- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR1256
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Origene geneexpression products in human, mouse, rat for MIR1256
- Browse OriGene miRNA Products For MIR1256
- GenScript: Custom all cDNA clones Services for MIR1256
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- Browse GenScript CRISPR for MIR1256
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MIR1256
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search GeneTex for Antibodies for MIR1256
- Search GeneTex for Proteins for MIR1256
- Search ViGene Biosciences for MIR1256
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR1256
- VectorBuilder custom plasmid, inducible vectors for MIR1256
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR1256
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR1256 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer