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Aliases for MIR1256 Gene

Subcategory (RNA class) for MIR1256 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1256 Gene

  • MicroRNA 1256 2 3 5
  • Hsa-Mir-1256 3
  • MIRN1256 3

External Ids for MIR1256 Gene

Previous HGNC Symbols for MIR1256 Gene

  • MIRN1256

Previous GeneCards Identifiers for MIR1256 Gene

  • GC00U923026
  • GC01M021188
  • GC01M021314

Summaries for MIR1256 Gene

Entrez Gene Summary for MIR1256 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1256 Gene

MIR1256 (MicroRNA 1256) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1256 Gene

Genomics for MIR1256 Gene

Regulatory Elements for MIR1256 Gene

Enhancers for MIR1256 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F021020 1.8 FANTOM5 Ensembl ENCODE 12.3 -33.7 -33712 2.6 HDGF PKNOX1 ARNT MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 HP1BP3 MIR1256 NBPF2P EIF4G3 ECE1 CDA GC01P021023 RPS15AP6
GH01F021148 1.5 FANTOM5 Ensembl ENCODE 11.1 -162.5 -162480 4.6 INSM2 KLF17 ZNF2 ZEB1 ZNF121 ZNF366 SCRT2 FOS KLF7 ZNF391 EIF4G3 MIR1256 HP1BP3 HSPE1P27 GC01M021094
GH01F020963 1.2 Ensembl ENCODE 12.5 +23.8 23813 2.0 HDAC1 ARID4B FEZF1 RAD21 ZNF335 GLIS2 GATA2 ETV6 CREM SP3 HP1BP3 MIR1256 EIF4G3 LOC105376829
GH01F021182 1.4 FANTOM5 Ensembl ENCODE 10.7 -195.3 -195268 2.6 BCOR CTCF ATF1 KLF17 RAD21 ZNF48 ZEB1 ZNF335 GLIS2 ZFHX2 HP1BP3 MIR1256 ECE1 EIF4G3 GC01M021203
GH01F021098 1.1 Ensembl ENCODE 11 -111.5 -111469 3.4 ZNF146 MAX ZNF121 ZNF316 GATA2 TRIM24 NFE2 FOS MAFK EZH2 EIF4G3 MIR1256 GC01M021094 HSPE1P27
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1256 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1256 Gene

Chromosome:
1
Start:
20,988,314 bp from pter
End:
20,988,432 bp from pter
Size:
119 bases
Orientation:
Minus strand

Genomic View for MIR1256 Gene

Genes around MIR1256 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1256 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1256 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1256 Gene

Proteins for MIR1256 Gene

Post-translational modifications for MIR1256 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1256 Gene

Domains & Families for MIR1256 Gene

Gene Families for MIR1256 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1256: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1256 Gene

Function for MIR1256 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1256 Gene

Localization for MIR1256 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1256 Gene

Pathways & Interactions for MIR1256 Gene

SuperPathways for MIR1256 Gene

No Data Available

Interacting Proteins for MIR1256 Gene

Gene Ontology (GO) - Biological Process for MIR1256 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1256 Gene

Transcripts for MIR1256 Gene

mRNA/cDNA for MIR1256 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1256 Gene

No ASD Table

Relevant External Links for MIR1256 Gene

GeneLoc Exon Structure for
MIR1256
ECgene alternative splicing isoforms for
MIR1256

Expression for MIR1256 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1256 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1256 Gene:

MIR1256
genes like me logo Genes that share expression patterns with MIR1256: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1256 Gene

Orthologs for MIR1256 Gene

Evolution for MIR1256 Gene

ENSEMBL:
Gene Tree for MIR1256 (if available)
TreeFam:
Gene Tree for MIR1256 (if available)

No data available for Orthologs for MIR1256 Gene

Paralogs for MIR1256 Gene

No data available for Paralogs for MIR1256 Gene

Variants for MIR1256 Gene

Sequence variations from dbSNP and Humsavar for MIR1256 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs113204385 -- 20,988,203(+) AAAGT(G/T)CAAGG intron-variant, downstream-variant-500B
rs113489286 -- 20,988,925(+) CCTGG(A/G)TGCAG intron-variant, upstream-variant-2KB
rs113733077 -- 20,989,081(+) GGGAG(A/G)GGAGA intron-variant, upstream-variant-2KB
rs114003638 -- 20,987,996(+) TTATT(C/G)CTGAT intron-variant, downstream-variant-500B
rs115048780 -- 20,987,976(+) AATGA(A/T)AAAGC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1256 Gene

Variant ID Type Subtype PubMed ID
nsv1009855 CNV loss 25217958
nsv1012238 CNV loss 25217958

Relevant External Links for MIR1256 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1256

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1256 Gene

Disorders for MIR1256 Gene

Relevant External Links for MIR1256

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1256

No disorders were found for MIR1256 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1256 Gene

Publications for MIR1256 Gene

  1. Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma. (PMID: 23361059) Takeshita N. … Matsubara H. (Br. J. Cancer 2013) 3 64
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1256 Gene

Sources for MIR1256 Gene

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