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Aliases for MIR1255A Gene

Subcategory (RNA class) for MIR1255A Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1255A Gene

  • MicroRNA 1255a 2 3 5
  • Hsa-Mir-1255a 3
  • MIRN1255A 3

External Ids for MIR1255A Gene

Previous HGNC Symbols for MIR1255A Gene

  • MIRN1255A

Previous GeneCards Identifiers for MIR1255A Gene

  • GC00U923007
  • GC04M102471
  • GC04M102251

Summaries for MIR1255A Gene

Entrez Gene Summary for MIR1255A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1255A Gene

MIR1255A (MicroRNA 1255a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1255A Gene

Genomics for MIR1255A Gene

Regulatory Elements for MIR1255A Gene

Enhancers for MIR1255A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G101354 1.4 Ensembl ENCODE dbSUPER 11.5 -26.1 -26091 3.6 ELF3 PKNOX1 FOXA2 TBL1XR1 SIN3A BMI1 DMAP1 RARA RFX5 GATA2 FLJ20021 MIR1255A PPP3CA BANK1
GH04G101306 0.7 Ensembl 12.7 +23.9 23914 0.6 ZNF146 TBL1XR1 FEZF1 ZFHX2 ZSCAN29 RELB PRDM10 IKZF2 EGR2 MTA2 MIR1255A PPP3CA FLJ20021 GC04M101296
GH04G101284 0.8 Ensembl ENCODE 11.1 +45.6 45637 0.8 GATA3 FOXA2 RFX1 ZNF384 BMI1 FOXA1 MIR1255A PPP3CA FLJ20021 GC04M101296 MIR8066
GH04G101305 0.7 Ensembl 12 +25.3 25314 0.2 FEZF1 CHD7 GATA3 GLI2 ZNF600 PRDM10 TCF7L2 GFI1B OVOL3 ZEB2 FLJ20021 MIR1255A PPP3CA GC04M101296
GH04G101171 0.5 ENCODE 11.2 +158.5 158476 0.2 ZSCAN21 JUN ZNF629 FOS ZNF24 MIR1255A FLJ20021 PPP3CA MIR8066 EMCN
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1255A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1255A Gene

Chromosome:
4
Start:
101,330,302 bp from pter
End:
101,330,414 bp from pter
Size:
113 bases
Orientation:
Minus strand

Genomic View for MIR1255A Gene

Genes around MIR1255A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1255A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1255A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1255A Gene

ORGUL Member Location for MIR1255A Gene

ORGUL Member Location for MIR1255A gene

Proteins for MIR1255A Gene

Post-translational modifications for MIR1255A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1255A Gene

Domains & Families for MIR1255A Gene

Gene Families for MIR1255A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1255A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1255A Gene

Function for MIR1255A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1255A Gene

Localization for MIR1255A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1255A Gene

Pathways & Interactions for MIR1255A Gene

SuperPathways for MIR1255A Gene

No Data Available

Interacting Proteins for MIR1255A Gene

Gene Ontology (GO) - Biological Process for MIR1255A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1255A Gene

Drugs & Compounds for MIR1255A Gene

No Compound Related Data Available

Transcripts for MIR1255A Gene

mRNA/cDNA for MIR1255A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1255A Gene

No ASD Table

Relevant External Links for MIR1255A Gene

GeneLoc Exon Structure for
MIR1255A
ECgene alternative splicing isoforms for
MIR1255A

Expression for MIR1255A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1255A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1255A Gene:

MIR1255A
genes like me logo Genes that share expression patterns with MIR1255A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1255A Gene

Orthologs for MIR1255A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1255A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 92 (a)
OneToOne
Species where no ortholog for MIR1255A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1255A Gene

ENSEMBL:
Gene Tree for MIR1255A (if available)
TreeFam:
Gene Tree for MIR1255A (if available)

Paralogs for MIR1255A Gene

No data available for Paralogs for MIR1255A Gene

Variants for MIR1255A Gene

Sequence variations from dbSNP and Humsavar for MIR1255A Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1001113833 -- 101,332,247(+) ATACA(A/G)ATGTG intron-variant, upstream-variant-2KB
rs1002869806 -- 101,330,159(+) TAACA(A/C)GAGTT intron-variant, downstream-variant-500B
rs1002888302 -- 101,331,360(+) TCATT(A/G)TTCTT intron-variant, upstream-variant-2KB
rs1003373657 -- 101,329,893(+) TTACT(A/G)CTCTT intron-variant, downstream-variant-500B
rs1003603882 -- 101,331,770(+) CCAAA(A/C/G)ATTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1255A Gene

Variant ID Type Subtype PubMed ID
nsv1011351 CNV gain 25217958
nsv950365 CNV duplication 24416366

Relevant External Links for MIR1255A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1255A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1255A Gene

Disorders for MIR1255A Gene

Relevant External Links for MIR1255A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1255A

No disorders were found for MIR1255A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1255A Gene

Publications for MIR1255A Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1255A Gene

Sources for MIR1255A Gene

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