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Aliases for MIR1254-2 Gene

Subcategory (RNA class) for MIR1254-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1254-2 Gene

  • MicroRNA 1254-2 2 3 5
  • Hsa-Mir-1254-2 3

External Ids for MIR1254-2 Gene

Previous GeneCards Identifiers for MIR1254-2 Gene

  • GC10U901542
  • GC10P023683

Summaries for MIR1254-2 Gene

Entrez Gene Summary for MIR1254-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1254-2 Gene

MIR1254-2 (MicroRNA 1254-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1254-2 Gene

Genomics for MIR1254-2 Gene

Regulatory Elements for MIR1254-2 Gene

Enhancers for MIR1254-2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR1254-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1254-2 Gene

Chromosome:
10
Start:
23,393,405 bp from pter
End:
23,393,467 bp from pter
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR1254-2 Gene

Genes around MIR1254-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1254-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1254-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1254-2 Gene

Proteins for MIR1254-2 Gene

Post-translational modifications for MIR1254-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1254-2 Gene

Domains & Families for MIR1254-2 Gene

Gene Families for MIR1254-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1254-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1254-2 Gene

Function for MIR1254-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1254-2 Gene

Localization for MIR1254-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1254-2 Gene

Pathways & Interactions for MIR1254-2 Gene

SuperPathways for MIR1254-2 Gene

No Data Available

Interacting Proteins for MIR1254-2 Gene

Gene Ontology (GO) - Biological Process for MIR1254-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1254-2 Gene

Drugs & Compounds for MIR1254-2 Gene

No Compound Related Data Available

Transcripts for MIR1254-2 Gene

mRNA/cDNA for MIR1254-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1254-2 Gene

No ASD Table

Relevant External Links for MIR1254-2 Gene

GeneLoc Exon Structure for
MIR1254-2
ECgene alternative splicing isoforms for
MIR1254-2

Expression for MIR1254-2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1254-2 Gene

Orthologs for MIR1254-2 Gene

Evolution for MIR1254-2 Gene

ENSEMBL:
Gene Tree for MIR1254-2 (if available)
TreeFam:
Gene Tree for MIR1254-2 (if available)

No data available for Orthologs for MIR1254-2 Gene

Paralogs for MIR1254-2 Gene

No data available for Paralogs for MIR1254-2 Gene

Variants for MIR1254-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1254-2 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1973617 -- 23,392,410(-) ataaG(A/G)TATGG upstream-variant-2KB
rs2012456 -- 23,392,833(-) tcagc(C/T)gcttg upstream-variant-2KB
rs2175502 -- 23,392,832(-) CAGCC(G/T)CTTGA upstream-variant-2KB
rs7095622 -- 23,393,899(+) CTGGG(A/T)TTACA downstream-variant-500B
rs12049727 -- 23,393,651(+) GTGAA(C/T)ACTCT downstream-variant-500B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR1254-2 Gene

Disorders for MIR1254-2 Gene

Relevant External Links for MIR1254-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1254-2

No disorders were found for MIR1254-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1254-2 Gene

Publications for MIR1254-2 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR1254-2 Gene

Sources for MIR1254-2 Gene

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