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Aliases for MIR1254-2 Gene

Subcategory (RNA class) for MIR1254-2 Gene


Quality Score for this RNA gene is


Aliases for MIR1254-2 Gene

  • MicroRNA 1254-2 2 3
  • Hsa-Mir-1254-2 3

External Ids for MIR1254-2 Gene

Previous GeneCards Identifiers for MIR1254-2 Gene

  • GC10U901542
  • GC10P023683

Summaries for MIR1254-2 Gene

Entrez Gene Summary for MIR1254-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1254-2 Gene

MIR1254-2 (MicroRNA 1254-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1254-2 Gene

Genomics for MIR1254-2 Gene

Genomic Location for MIR1254-2 Gene

23,393,405 bp from pter
23,393,467 bp from pter
63 bases
Plus strand

Genomic View for MIR1254-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1254-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1254-2 Gene

No data available for Regulatory Elements for MIR1254-2 Gene

Proteins for MIR1254-2 Gene

Post-translational modifications for MIR1254-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1254-2 Gene

Domains for MIR1254-2 Gene

Gene Families for MIR1254-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1254-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1254-2 Gene

Function for MIR1254-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1254-2 Gene

Localization for MIR1254-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1254-2 Gene

Pathways for MIR1254-2 Gene

SuperPathways for MIR1254-2 Gene

No Data Available

Interacting Proteins for MIR1254-2 Gene

Gene Ontology (GO) - Biological Process for MIR1254-2 Gene


No data available for Pathways by source for MIR1254-2 Gene

Transcripts for MIR1254-2 Gene

mRNA/cDNA for MIR1254-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1254-2 Gene

No ASD Table

Relevant External Links for MIR1254-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1254-2 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR1254-2 Gene

Orthologs for MIR1254-2 Gene

Evolution for MIR1254-2 Gene

Gene Tree for MIR1254-2 (if available)
Gene Tree for MIR1254-2 (if available)

No data available for Orthologs for MIR1254-2 Gene

Paralogs for MIR1254-2 Gene

No data available for Paralogs for MIR1254-2 Gene

Variants for MIR1254-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1254-2 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1973617 -- 23,392,410(-) ataaG(A/G)TATGG upstream-variant-2KB
rs2012456 -- 23,392,833(-) tcagc(C/T)gcttg upstream-variant-2KB
rs2175502 -- 23,392,832(-) CAGCC(G/T)CTTGA upstream-variant-2KB
rs5783842 -- 23,392,239(+) TACTT(-/A)ACAAT upstream-variant-2KB
rs7095622 -- 23,393,899(+) CTGGG(A/T)TTACA downstream-variant-500B

Relevant External Links for MIR1254-2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR1254-2 Gene

Disorders for MIR1254-2 Gene

No disorders were found for MIR1254-2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR1254-2 Gene

Publications for MIR1254-2 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR1254-2 Gene

Sources for MIR1254-2 Gene

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