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Aliases for MIR1254-1 Gene

Subcategory (RNA class) for MIR1254-1 Gene


Quality Score for this RNA gene is


Aliases for MIR1254-1 Gene

  • MicroRNA 1254-1 2 3
  • MicroRNA 1254 2 3
  • Hsa-Mir-1254-1 3
  • Hsa-Mir-1254 3
  • MIRN1254 3
  • MIR1254 3

External Ids for MIR1254-1 Gene

Previous HGNC Symbols for MIR1254-1 Gene

  • MIRN1254
  • MIR1254

Previous GeneCards Identifiers for MIR1254-1 Gene

  • GC10P070520
  • GC10P070521
  • GC10P070524
  • GC10P070527

Summaries for MIR1254-1 Gene

Entrez Gene Summary for MIR1254-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1254-1 Gene

MIR1254-1 (MicroRNA 1254-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1254-1 Gene

Genomics for MIR1254-1 Gene

Genomic Location for MIR1254-1 Gene

68,759,318 bp from pter
68,759,414 bp from pter
97 bases
Plus strand

Genomic View for MIR1254-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1254-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1254-1 Gene

No data available for Regulatory Elements for MIR1254-1 Gene

Proteins for MIR1254-1 Gene

Post-translational modifications for MIR1254-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1254-1 Gene

Domains & Families for MIR1254-1 Gene

Gene Families for MIR1254-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1254-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1254-1 Gene

Function for MIR1254-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1254-1 Gene

Localization for MIR1254-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1254-1 Gene

Pathways & Interactions for MIR1254-1 Gene

SuperPathways for MIR1254-1 Gene

No Data Available

Interacting Proteins for MIR1254-1 Gene

Gene Ontology (GO) - Biological Process for MIR1254-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1254-1 Gene

Drugs & Compounds for MIR1254-1 Gene

No Compound Related Data Available

Transcripts for MIR1254-1 Gene

mRNA/cDNA for MIR1254-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1254-1 Gene

No ASD Table

Relevant External Links for MIR1254-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1254-1 Gene

mRNA expression in normal human tissues for MIR1254-1 Gene

genes like me logo Genes that share expression patterns with MIR1254-1: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1254-1 Gene

Orthologs for MIR1254-1 Gene

Evolution for MIR1254-1 Gene

Gene Tree for MIR1254-1 (if available)
Gene Tree for MIR1254-1 (if available)

No data available for Orthologs for MIR1254-1 Gene

Paralogs for MIR1254-1 Gene

No data available for Paralogs for MIR1254-1 Gene

Variants for MIR1254-1 Gene

Relevant External Links for MIR1254-1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1254-1 Gene

Disorders for MIR1254-1 Gene

Relevant External Links for MIR1254-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR1254-1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1254-1 Gene

Publications for MIR1254-1 Gene

  1. miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer. (PMID: 21258252) Foss K.M. … Weiss G.J. (J Thorac Oncol 2011) 67
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 67
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR1254-1 Gene

Sources for MIR1254-1 Gene

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