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Aliases for MIR1251 Gene

Subcategory (RNA class) for MIR1251 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1251 Gene

  • MicroRNA 1251 2 3
  • Hsa-Mir-1251 3
  • MIRN1251 3

External Ids for MIR1251 Gene

Previous Symbols for MIR1251 Gene

  • MIRN1251

Summaries for MIR1251 Gene

Entrez Gene Summary for MIR1251 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1251 Gene

MIR1251 (MicroRNA 1251) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1251 Gene

Genomics for MIR1251 Gene

Genomic Location for MIR1251 Gene

Start:
97,491,900 bp from pter
End:
97,491,983 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR1251 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1251 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1251 Gene

No data available for Regulatory Elements for MIR1251 Gene

Proteins for MIR1251 Gene

Post-translational modifications for MIR1251 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1251 Gene

Domains for MIR1251 Gene

Gene Families for MIR1251 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR1251: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR1251 Gene

Function for MIR1251 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1251 Gene

Localization for MIR1251 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR1251 Gene

Pathways for MIR1251 Gene

SuperPathways for MIR1251 Gene

No Data Available

Interacting Proteins for MIR1251 Gene

Gene Ontology (GO) - Biological Process for MIR1251 Gene

None

No data available for Pathways by source for MIR1251 Gene

Transcripts for MIR1251 Gene

mRNA/cDNA for MIR1251 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1251 Gene

No ASD Table

Relevant External Links for MIR1251 Gene

GeneLoc Exon Structure for
MIR1251
ECgene alternative splicing isoforms for
MIR1251

Expression for MIR1251 Gene

mRNA expression in normal human tissues for MIR1251 Gene

genes like me logo Genes that share expressions with MIR1251: view

Orthologs for MIR1251 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1251 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1251 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-1251 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir1251 37
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-1251 37
  • 89 (a)
OneToOne
Species with no ortholog for MIR1251:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1251 Gene

ENSEMBL:
Gene Tree for MIR1251 (if available)
TreeFam:
Gene Tree for MIR1251 (if available)

Paralogs for MIR1251 Gene

No data available for Paralogs for MIR1251 Gene

Variants for MIR1251 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1251 Gene

Variant ID Type Subtype PubMed ID
nsv7234 OTHER Inversion 18451855
nsv832495 CNV Gain 17160897
nsv438229 CNV Loss 16468122

Relevant External Links for MIR1251 Gene

HapMap Linkage Disequilibrium report
MIR1251

No data available for Sequence variations from dbSNP and Humsavar for MIR1251 Gene

Disorders for MIR1251 Gene

No disorders were found for MIR1251 Gene.

No data available for UniProtKB/Swiss-Prot for MIR1251 Gene

Publications for MIR1251 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. Hidden layers of human small RNAs. (PMID: 18402656) Kawaji H. … Hayashizaki Y. (BMC Genomics 2008) 3
  4. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3

Products for MIR1251 Gene

Sources for MIR1251 Gene

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