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Aliases for MIR1250 Gene

Subcategory (RNA class) for MIR1250 Gene


Quality Score for this RNA gene is


Aliases for MIR1250 Gene

  • MicroRNA 1250 2 3 5
  • Hsa-Mir-1250 3
  • Mir-1250 3
  • MIRN1250 3

External Ids for MIR1250 Gene

Previous HGNC Symbols for MIR1250 Gene

  • MIRN1250

Previous GeneCards Identifiers for MIR1250 Gene

  • GC00U923150
  • GC17M076722
  • GC17M079106

Summaries for MIR1250 Gene

Entrez Gene Summary for MIR1250 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1250 Gene

MIR1250 (MicroRNA 1250) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1250 Gene

Genomics for MIR1250 Gene

Regulatory Elements for MIR1250 Gene

Enhancers for MIR1250 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F081101 1.4 Ensembl ENCODE 11.9 +31.6 31624 1.0 HDGF PKNOX1 MLX WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 AATK MIR1250 CEP131 GC17M081121 BAIAP2
GH17F081081 1.3 Ensembl ENCODE 12.1 +49.6 49620 4.9 PKNOX1 MLX ARID4B DMAP1 ZNF48 YY1 SLC30A9 MCM3 SP5 ZHX2 MIR1250 AATK BAIAP2 RPTOR CEP131 GC17M081121
GH17F081163 1 ENCODE 11.8 -31.6 -31598 2.3 MLX ZFP64 ARID4B DMAP1 ZNF48 ZNF2 ZNF121 GLIS2 MXD4 MIER2 LOC100294362 ENSG00000262049 CEP131 GPS1 MIR1250 AATK ENSG00000265678 ARL16 RFNG ENSG00000262877
GH17F081158 0.8 Ensembl ENCODE 11.8 -26.8 -26793 2.6 ZNF664 ZNF263 ZSCAN16 MNT ZIC2 E2F6 EGR2 MIR1250 AATK LINC00482 SLC38A10 AATK-AS1 GC17P081143
GH17F081071 0.8 ENCODE 11.5 +61.2 61150 2.0 ARID4B RAD21 ZNF48 GLIS2 SCRT2 ZNF143 CREM THAP11 DEK MIXL1 MIR1250 AATK BAIAP2 GC17M081121
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1250 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1250 Gene

81,133,196 bp from pter
81,133,308 bp from pter
113 bases
Minus strand

Genomic View for MIR1250 Gene

Genes around MIR1250 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1250 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1250 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1250 Gene

ORGUL Member Location for MIR1250 Gene

ORGUL Member Location for MIR1250 gene

Proteins for MIR1250 Gene

Post-translational modifications for MIR1250 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1250 Gene

Domains & Families for MIR1250 Gene

Gene Families for MIR1250 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1250: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1250 Gene

Function for MIR1250 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1250 Gene

Localization for MIR1250 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1250 Gene

Pathways & Interactions for MIR1250 Gene

SuperPathways for MIR1250 Gene

No Data Available

Interacting Proteins for MIR1250 Gene

Gene Ontology (GO) - Biological Process for MIR1250 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1250 Gene

Transcripts for MIR1250 Gene

mRNA/cDNA for MIR1250 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1250 Gene

No ASD Table

Relevant External Links for MIR1250 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1250 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1250 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1250 Gene

This gene is overexpressed in Brain - Cerebellum (x8.9), Whole Blood (x7.9), Brain - Cerebellar Hemisphere (x7.1), and Pituitary (x4.6).

NURSA nuclear receptor signaling pathways regulating expression of MIR1250 Gene:

genes like me logo Genes that share expression patterns with MIR1250: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1250 Gene

Orthologs for MIR1250 Gene

Evolution for MIR1250 Gene

Gene Tree for MIR1250 (if available)
Gene Tree for MIR1250 (if available)

No data available for Orthologs for MIR1250 Gene

Paralogs for MIR1250 Gene

No data available for Paralogs for MIR1250 Gene

Variants for MIR1250 Gene

Sequence variations from dbSNP and Humsavar for MIR1250 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs111499557 -- 81,135,098(+) CCAGG(C/T)CCCTC intron-variant, upstream-variant-2KB
rs112566905 -- 81,134,281(+) GCCCC(A/G)GGAAG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs112898360 -- 81,134,163(+) AAAGT(C/T)GAGGA intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs11650662 -- 81,132,775(+) CCCAG(C/T)GCAGG intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs11653179 -- 81,134,990(+) GGTGC(A/G)GGGAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1250 Gene

Variant ID Type Subtype PubMed ID
dgv3292n100 CNV gain 25217958
esv26223 CNV gain+loss 19812545
nsv952388 CNV deletion 24416366
nsv833564 CNV loss 17160897
nsv828128 CNV loss 20364138
nsv523417 CNV gain 19592680
nsv470619 CNV loss 18288195
nsv1066947 CNV loss 25217958
nsv1065052 CNV gain 25217958
esv3641392 CNV gain 21293372

Relevant External Links for MIR1250 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1250 Gene

Disorders for MIR1250 Gene

Relevant External Links for MIR1250

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1250 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1250 Gene

Publications for MIR1250 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1250 Gene

Sources for MIR1250 Gene

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