Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1250 Gene

Subcategory (RNA class) for MIR1250 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1250 Gene

  • MicroRNA 1250 2 3 5
  • Hsa-Mir-1250 3
  • Mir-1250 3
  • MIRN1250 3

External Ids for MIR1250 Gene

Previous HGNC Symbols for MIR1250 Gene

  • MIRN1250

Previous GeneCards Identifiers for MIR1250 Gene

  • GC00U923150
  • GC17M076722
  • GC17M079106

Summaries for MIR1250 Gene

Entrez Gene Summary for MIR1250 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1250 Gene

MIR1250 (MicroRNA 1250) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1250 Gene

Genomics for MIR1250 Gene

Regulatory Elements for MIR1250 Gene

Promoters for MIR1250 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR1250 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1250 Gene

Chromosome:
17
Start:
81,133,196 bp from pter
End:
81,133,308 bp from pter
Size:
113 bases
Orientation:
Minus strand

Genomic View for MIR1250 Gene

Genes around MIR1250 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1250 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1250 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1250 Gene

ORGUL Member Location for MIR1250 Gene

ORGUL Member Location for MIR1250 gene

Proteins for MIR1250 Gene

Post-translational modifications for MIR1250 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1250 Gene

Domains & Families for MIR1250 Gene

Gene Families for MIR1250 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1250: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1250 Gene

Function for MIR1250 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1250 Gene

Localization for MIR1250 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1250 Gene

Pathways & Interactions for MIR1250 Gene

SuperPathways for MIR1250 Gene

No Data Available

Interacting Proteins for MIR1250 Gene

Gene Ontology (GO) - Biological Process for MIR1250 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1250 Gene

Drugs & Compounds for MIR1250 Gene

No Compound Related Data Available

Transcripts for MIR1250 Gene

mRNA/cDNA for MIR1250 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1250 Gene

No ASD Table

Relevant External Links for MIR1250 Gene

GeneLoc Exon Structure for
MIR1250
ECgene alternative splicing isoforms for
MIR1250

Expression for MIR1250 Gene

mRNA expression in normal human tissues for MIR1250 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1250 Gene

This gene is overexpressed in Brain - Cerebellum (x8.9), Whole Blood (x7.9), Brain - Cerebellar Hemisphere (x7.1), and Pituitary (x4.6).
genes like me logo Genes that share expression patterns with MIR1250: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1250 Gene

Orthologs for MIR1250 Gene

Evolution for MIR1250 Gene

ENSEMBL:
Gene Tree for MIR1250 (if available)
TreeFam:
Gene Tree for MIR1250 (if available)

No data available for Orthologs for MIR1250 Gene

Paralogs for MIR1250 Gene

No data available for Paralogs for MIR1250 Gene

Variants for MIR1250 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1250 Gene

Variant ID Type Subtype PubMed ID
esv26223 CNV Gain+Loss 19812545
nsv828128 CNV Loss 20364138
dgv3304n71 CNV Loss 21882294
nsv909000 CNV Loss 21882294
dgv3308n71 CNV Loss 21882294
nsv833564 CNV Loss 17160897
nsv909021 CNV Loss 21882294
nsv470619 CNV Loss 18288195
dgv3310n71 CNV Loss 21882294
dgv3311n71 CNV Loss 21882294
dgv3312n71 CNV Loss 21882294
dgv3313n71 CNV Loss 21882294
nsv909037 CNV Loss 21882294
dgv3314n71 CNV Loss 21882294
nsv523417 CNV Gain 19592680
nsv909047 CNV Gain 21882294
dgv3315n71 CNV Loss 21882294
dgv3316n71 CNV Loss 21882294
nsv909052 CNV Loss 21882294

Relevant External Links for MIR1250 Gene

HapMap Linkage Disequilibrium report
MIR1250

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR1250 Gene

Disorders for MIR1250 Gene

Relevant External Links for MIR1250

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1250

No disorders were found for MIR1250 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1250 Gene

Publications for MIR1250 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 67
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR1250 Gene

Sources for MIR1250 Gene

Back to Top

Content