Aliases for MIR1250 Gene
Subcategory (RNA class) for MIR1250 Gene
Quality Score for this RNA gene is
External Ids for MIR1250 Gene
- HGNC: 35316
- Entrez Gene: 100302229
- Ensembl: ENSG00000221025
- miRBase: hsa-mir-1250
ORGUL Members for MIR1250 Gene
Previous HGNC Symbols for MIR1250 Gene
- MIRN1250
Previous GeneCards Identifiers for MIR1250 Gene
- GC00U923150
- GC17M076722
- GC17M079106
Summaries for MIR1250 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR1250 Gene
MIR1250 (MicroRNA 1250) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR1250 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1250 Gene
Genomics for MIR1250 Gene
GeneHancer (GH) Regulatory Elements for MIR1250 Gene
Regulatory Element Products
Genomic Locations for MIR1250 Gene
- chr17:81,133,196-81,133,308
- (GRCh38/hg38)
- Size:
- 113 bases
- Orientation:
- Minus strand
- chr17:79,106,996-79,107,108
- (GRCh37/hg19)
Genomic View for MIR1250 Gene
- Cytogenetic band:
-
- 17q25.3 by Ensembl
- 17q25.3 by Entrez Gene
- 17q25.3 by HGNC


RefSeq DNA sequence for MIR1250 Gene
ORGUL Member Location for MIR1250 Gene

Proteins for MIR1250 Gene
Post-translational modifications for MIR1250 Gene
Antibody Products
- Search GeneTex for Antibodies for MIR1250
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR1250
- Origene Custom Protein Services for MIR1250
- Search GeneTex for Proteins for MIR1250
No data available for DME Specific Peptides for MIR1250 Gene
Domains & Families for MIR1250 Gene
Gene Families for MIR1250 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1250 Gene
Function for MIR1250 Gene
Phenotypes From GWAS Catalog for MIR1250 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR1250
-
- Search ViGene Biosciences for MIR1250
CRISPR Products
- Browse CRISPR knockouts for MIR1250
- Applied Biological Materials CRISPR for MIR1250
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR1250
Clone Products
- GenScript: Custom all cDNA clones Services for MIR1250
- VectorBuilder custom plasmid, inducible vectors for MIR1250
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR1250
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR1250
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1250 Gene
Localization for MIR1250 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1250 Gene
Transcripts for MIR1250 Gene
mRNA/cDNA for MIR1250 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR1250
- Applied Biological Materials CRISPR for MIR1250
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR1250
Clone Products
- GenScript: Custom all cDNA clones Services for MIR1250
- VectorBuilder custom plasmid, inducible vectors for MIR1250
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR1250
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR1250
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR1250 Gene
mRNA differential expression in normal tissues according to GTEx for MIR1250 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR1250 Gene:
MIR1250Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1250 Gene
Orthologs for MIR1250 Gene
No data available for Orthologs for MIR1250 Gene
Paralogs for MIR1250 Gene
No data available for Paralogs for MIR1250 Gene
Variants for MIR1250 Gene
SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000206511 | -- | 81,133,971(-) | C/A | upstream_transcript_variant | |
rs1000237787 | -- | 81,133,711(-) | G/A | upstream_transcript_variant | |
rs1001424638 | -- | 81,134,221(-) | C/T | upstream_transcript_variant | |
rs1002347105 | -- | 81,134,851(-) | C/G | upstream_transcript_variant | |
rs1002397827 | -- | 81,133,394(-) | T/C | upstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv3292n100 | CNV | gain | 25217958 |
esv26223 | CNV | gain+loss | 19812545 |
esv3641392 | CNV | gain | 21293372 |
nsv1065052 | CNV | gain | 25217958 |
nsv1066947 | CNV | loss | 25217958 |
nsv470619 | CNV | loss | 18288195 |
nsv523417 | CNV | gain | 19592680 |
nsv828128 | CNV | loss | 20364138 |
nsv833564 | CNV | loss | 17160897 |
nsv952388 | CNV | deletion | 24416366 |
Additional Variant Information for MIR1250 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR1250
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1250 Gene
Disorders for MIR1250 Gene
Additional Disease Information for MIR1250
No disorders were found for MIR1250 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1250 Gene
Publications for MIR1250 Gene
- Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
- Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
Products for MIR1250 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
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- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
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- Browse OriGene Antibodies
- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR1250
- Origene Custom Protein Services for MIR1250
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- Browse CRISPR knockouts for MIR1250
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR1250
- GenScript: Custom all cDNA clones Services for MIR1250
- GenScript Custom Purified and Recombinant Proteins Services for MIR1250
- GenScript Custom Assay Services for MIR1250
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- Design optimal peptide antigens
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- Sino Biological Transfection Reagent
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
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- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR1250
- VectorBuilder custom plasmid, inducible vectors for MIR1250
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR1250
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR1250
- Search GeneTex for Proteins for MIR1250
Sources for MIR1250 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew