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Aliases for MIR1249 Gene

Subcategory (RNA class) for MIR1249 Gene


Quality Score for this RNA gene is


Aliases for MIR1249 Gene

  • MicroRNA 1249 2 3
  • Hsa-Mir-1249 3
  • MIRN1249 3

External Ids for MIR1249 Gene

Previous HGNC Symbols for MIR1249 Gene

  • MIRN1249

Previous GeneCards Identifiers for MIR1249 Gene

  • GC00U922971
  • GC22M043976
  • GC22M045596

Summaries for MIR1249 Gene

Entrez Gene Summary for MIR1249 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1249 Gene

MIR1249 (MicroRNA 1249) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1249 Gene

Genomics for MIR1249 Gene

Genomic Location for MIR1249 Gene

45,200,938 bp from pter
45,201,049 bp from pter
112 bases
Minus strand

Genomic View for MIR1249 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1249 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1249 Gene

No data available for Regulatory Elements for MIR1249 Gene

Proteins for MIR1249 Gene

Post-translational modifications for MIR1249 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1249 Gene

Domains for MIR1249 Gene

Gene Families for MIR1249 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1249: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1249 Gene

Function for MIR1249 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1249 Gene

Localization for MIR1249 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1249 Gene

Pathways for MIR1249 Gene

SuperPathways for MIR1249 Gene

No Data Available

Interacting Proteins for MIR1249 Gene

Gene Ontology (GO) - Biological Process for MIR1249 Gene


No data available for Pathways by source for MIR1249 Gene

Transcripts for MIR1249 Gene

mRNA/cDNA for MIR1249 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1249 Gene

No ASD Table

Relevant External Links for MIR1249 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1249 Gene

mRNA expression in normal human tissues for MIR1249 Gene

genes like me logo Genes that share expressions with MIR1249: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR1249 Gene

Orthologs for MIR1249 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1249 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-1249 36
  • 95 (a)
(Canis familiaris)
Mammalia -- 36
  • 53 (a)
(Mus musculus)
Mammalia Mir1249 36
  • 64 (a)
(Pan troglodytes)
Mammalia ptr-mir-1249 36
  • 100 (a)
Species with no ortholog for MIR1249:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1249 Gene

Gene Tree for MIR1249 (if available)
Gene Tree for MIR1249 (if available)

Paralogs for MIR1249 Gene

No data available for Paralogs for MIR1249 Gene

Variants for MIR1249 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1249 Gene

Variant ID Type Subtype PubMed ID
nsv834220 CNV Loss 17160897
dgv1411e1 CNV Complex 17122850
nsv829278 CNV Loss 20364138

Relevant External Links for MIR1249 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR1249 Gene

Disorders for MIR1249 Gene

No disorders were found for MIR1249 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR1249 Gene

Publications for MIR1249 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3

Products for MIR1249 Gene

Sources for MIR1249 Gene

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