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Aliases for MIR1247 Gene

Subcategory (RNA class) for MIR1247 Gene


Quality Score for this RNA gene is


Aliases for MIR1247 Gene

  • MicroRNA 1247 2 3 5
  • Hsa-Mir-1247 3
  • Mir-1247 3
  • MIRN1247 3

External Ids for MIR1247 Gene

Previous HGNC Symbols for MIR1247 Gene

  • MIRN1247

Previous GeneCards Identifiers for MIR1247 Gene

  • GC00U923082
  • GC14M101097
  • GC14M102026

Summaries for MIR1247 Gene

Entrez Gene Summary for MIR1247 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1247 Gene

MIR1247 (MicroRNA 1247) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1247 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1247 Gene

Genomics for MIR1247 Gene

Regulatory Elements for MIR1247 Gene

Enhancers for MIR1247 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H100769 1.5 FANTOM5 ENCODE dbSUPER 9.7 +784.8 784805 12.7 HDGF PKNOX1 ATF1 ARNT TCF12 ZNF766 GATA2 ELK1 ATF7 CAVIN1 DLK1 MIR1247 DIO3 EVL MEG3 PIR41786
GH14H101628 1.1 Ensembl ENCODE 10.7 -68.2 -68200 1.2 RB1 SIN3A ZNF2 THRB RAD21 RARA ZNF143 ATF7 RUNX3 CREM DIO3 MIR1247 ENSG00000258919 LOC105370675
GH14H101405 0.8 ENCODE 10.4 +154.8 154784 0.3 FOXA2 NFIB MAX ZBTB40 RAD21 YY1 HNF4G USF2 CEBPB REST MIR1247 DIO3 ENSG00000222185 SNORD114-31 ENSG00000222095 MIR493 RTL1 MIR433 MIR431 MIR136
GH14H101004 0.8 Ensembl ENCODE 9 +555.3 555338 1.9 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR154 MIR323B MIR485 MIR377 MIR496 MIR376C MIR1185-1 MIR1185-2
GH14H101518 0.5 ENCODE 11.9 +41.7 41704 0.2 ZBTB33 RAD21 NR2F2 DIO3 MIR1247 GC14P103098 LOC105370672
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1247 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1247 Gene

Genomic Locations for MIR1247 Gene
136 bases
Minus strand

Genomic View for MIR1247 Gene

Genes around MIR1247 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1247 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1247 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1247 Gene

Proteins for MIR1247 Gene

Post-translational modifications for MIR1247 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1247 Gene

Domains & Families for MIR1247 Gene

Gene Families for MIR1247 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1247: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1247 Gene

Function for MIR1247 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1247 Gene

Localization for MIR1247 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1247 Gene

Pathways & Interactions for MIR1247 Gene

SuperPathways for MIR1247 Gene

No Data Available

Interacting Proteins for MIR1247 Gene

Gene Ontology (GO) - Biological Process for MIR1247 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1247 Gene

Drugs & Compounds for MIR1247 Gene

No Compound Related Data Available

Transcripts for MIR1247 Gene

mRNA/cDNA for MIR1247 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1247 Gene

No ASD Table

Relevant External Links for MIR1247 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1247 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1247 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1247 Gene

Orthologs for MIR1247 Gene

Evolution for MIR1247 Gene

Gene Tree for MIR1247 (if available)
Gene Tree for MIR1247 (if available)

No data available for Orthologs for MIR1247 Gene

Paralogs for MIR1247 Gene

No data available for Paralogs for MIR1247 Gene

Variants for MIR1247 Gene

Sequence variations from dbSNP and Humsavar for MIR1247 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1001107414 -- 101,560,676(+) CCGCG(G/T)CGCCC upstream-variant-2KB
rs1001117243 -- 101,560,810(+) GCGGC(A/C)GTGTG upstream-variant-2KB
rs1002469076 -- 101,560,554(+) GGGGG(A/C)GCAGG upstream-variant-2KB
rs1002624007 -- 101,560,891(+) GAGCC(A/G)GGAAG upstream-variant-2KB
rs1003043577 -- 101,561,075(+) AGCTC(A/C)GGCGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1247 Gene

Variant ID Type Subtype PubMed ID
nsv952247 CNV deletion 24416366
nsv827061 CNV gain 20364138
nsv827060 CNV gain 20364138
nsv565882 CNV loss 21841781
nsv565881 CNV gain+loss 21841781
nsv565880 CNV loss 21841781
nsv565879 CNV loss 21841781
nsv1047869 CNV gain 25217958
esv29376 CNV loss 19812545
dgv388n67 CNV gain 20364138
dgv1978n100 CNV gain 25217958

Relevant External Links for MIR1247 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1247 Gene

Disorders for MIR1247 Gene

Relevant External Links for MIR1247

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1247 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1247 Gene

Publications for MIR1247 Gene

  1. MiR-1247-5p is overexpressed in castration resistant prostate cancer and targets MYCBP2. (PMID: 25731699) Scaravilli M … Visakorpi T (The Prostate 2015) 3 60
  2. MiRNA profile of osteosarcoma with CD117 and stro-1 expression: miR-1247 functions as an onco-miRNA by targeting MAP3K9. (PMID: 25973030) Zhao F … Chen Y (International journal of clinical and experimental pathology 2015) 3 60
  3. Epigenetically regulated MIR941 and MIR1247 target gastric cancer cell growth and migration. (PMID: 24785261) Kim JG … Yi JM (Epigenetics 2014) 3 60
  4. miR-1247 functions by targeting cartilage transcription factor SOX9. (PMID: 24014021) Martinez-Sanchez A … Murphy CL (The Journal of biological chemistry 2013) 3 60
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60

Products for MIR1247 Gene

Sources for MIR1247 Gene

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