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Aliases for MIR1246 Gene

Subcategory (RNA class) for MIR1246 Gene


Quality Score for this RNA gene is


Aliases for MIR1246 Gene

  • MicroRNA 1246 2 3 5
  • Hsa-Mir-1246 3
  • MIRN1246 3

External Ids for MIR1246 Gene

Previous HGNC Symbols for MIR1246 Gene

  • MIRN1246

Previous GeneCards Identifiers for MIR1246 Gene

  • GC00U922927
  • GC02M177173
  • GC02M177466

Summaries for MIR1246 Gene

Entrez Gene Summary for MIR1246 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1246 Gene

MIR1246 (MicroRNA 1246) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1246 Gene

Genomics for MIR1246 Gene

Regulatory Elements for MIR1246 Gene

Enhancers for MIR1246 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR1246 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1246 Gene

176,600,980 bp from pter
176,601,052 bp from pter
73 bases
Minus strand

Genomic View for MIR1246 Gene

Genes around MIR1246 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1246 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1246 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1246 Gene

Proteins for MIR1246 Gene

Post-translational modifications for MIR1246 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1246 Gene

Domains & Families for MIR1246 Gene

Gene Families for MIR1246 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1246: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1246 Gene

Function for MIR1246 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1246 Gene

Localization for MIR1246 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1246 Gene

Pathways & Interactions for MIR1246 Gene

SuperPathways for MIR1246 Gene

No Data Available

Interacting Proteins for MIR1246 Gene

Gene Ontology (GO) - Biological Process for MIR1246 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1246 Gene

Drugs & Compounds for MIR1246 Gene

No Compound Related Data Available

Transcripts for MIR1246 Gene

mRNA/cDNA for MIR1246 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1246 Gene

No ASD Table

Relevant External Links for MIR1246 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1246 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1246 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1246 Gene

Orthologs for MIR1246 Gene

Evolution for MIR1246 Gene

Gene Tree for MIR1246 (if available)
Gene Tree for MIR1246 (if available)

No data available for Orthologs for MIR1246 Gene

Paralogs for MIR1246 Gene

No data available for Paralogs for MIR1246 Gene

Variants for MIR1246 Gene

Sequence variations from dbSNP and Humsavar for MIR1246 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs7579043 -- 176,601,753(+) TGTAG(C/G)GTTTT upstream-variant-2KB
rs7585769 -- 176,603,036(+) ATAAG(A/G)GAAAA upstream-variant-2KB
rs986932 -- 176,601,416(-) AGTAA(A/C)TATGT upstream-variant-2KB
rs17343601 -- 176,600,867(+) CAGTG(C/T)TTGCA downstream-variant-500B
rs2969336 -- 176,602,395(+) CCATT(G/T)ACATT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1246 Gene

Variant ID Type Subtype PubMed ID
esv3593451 CNV loss 21293372
nsv834464 CNV gain 17160897

Relevant External Links for MIR1246 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1246 Gene

Disorders for MIR1246 Gene

Relevant External Links for MIR1246

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1246 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1246 Gene

Publications for MIR1246 Gene

  1. Down-regulation of miR-1246 in cervical cancer tissues and its clinical significance. (PMID: 26074491) Yang Y. … Zhang Y. (Gynecol. Oncol. 2015) 3 65
  2. Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene. (PMID: 26176629) Sarachana T. … Atreya C.D. (PLoS ONE 2015) 3 65
  3. The microRNA-1246 promotes metastasis in non-small cell lung cancer by targeting cytoplasmic polyadenylation element-binding protein 4. (PMID: 26209100) Huang W. … Luo R. (Diagn Pathol 2015) 3 65
  4. Overexpression of miR-595 and miR-1246 in the sera of patients with active forms of inflammatory bowel disease. (PMID: 25628040) Krissansen G.W. … Fraser A.G. (Inflamm. Bowel Dis. 2015) 3 65
  5. Expression and clinical significance of microRNA-1246 in human oral squamous cell carcinoma. (PMID: 25791131) Liao L. … Zhang M. (Med. Sci. Monit. 2015) 3 65

Products for MIR1246 Gene

Sources for MIR1246 Gene

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