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Aliases for MIR1246 Gene

Subcategory (RNA class) for MIR1246 Gene


Quality Score for this RNA gene is


Aliases for MIR1246 Gene

  • MicroRNA 1246 2 3
  • Hsa-Mir-1246 3
  • MIRN1246 3

External Ids for MIR1246 Gene

Previous HGNC Symbols for MIR1246 Gene

  • MIRN1246

Previous GeneCards Identifiers for MIR1246 Gene

  • GC00U922927
  • GC02M177173
  • GC02M177466

Summaries for MIR1246 Gene

Entrez Gene Summary for MIR1246 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1246 Gene

MIR1246 (MicroRNA 1246) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1246 Gene

Genomics for MIR1246 Gene

Genomic Location for MIR1246 Gene

176,600,980 bp from pter
176,601,052 bp from pter
73 bases
Minus strand

Genomic View for MIR1246 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1246 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1246 Gene

No data available for Regulatory Elements for MIR1246 Gene

Proteins for MIR1246 Gene

Post-translational modifications for MIR1246 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1246 Gene

Domains & Families for MIR1246 Gene

Gene Families for MIR1246 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1246: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1246 Gene

Function for MIR1246 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1246 Gene

Localization for MIR1246 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1246 Gene

Pathways & Interactions for MIR1246 Gene

SuperPathways for MIR1246 Gene

No Data Available

Interacting Proteins for MIR1246 Gene

Gene Ontology (GO) - Biological Process for MIR1246 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1246 Gene

Drugs & Compounds for MIR1246 Gene

No Compound Related Data Available

Transcripts for MIR1246 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1246 Gene

No ASD Table

Relevant External Links for MIR1246 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

No data available for mRNA/cDNA for MIR1246 Gene

Expression for MIR1246 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1246 Gene

Orthologs for MIR1246 Gene

No data available for Orthologs and Evolution for MIR1246 Gene

Paralogs for MIR1246 Gene

No data available for Paralogs for MIR1246 Gene

Variants for MIR1246 Gene

Sequence variations from dbSNP and Humsavar for MIR1246 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs986932 -- 176,601,416(-) AGTAA(A/C)TATGT upstream-variant-2KB
rs2969336 -- 176,602,395(+) CCATT(G/T)ACATT upstream-variant-2KB
rs2969337 -- 176,602,657(+) GACCC(A/G)TTTTT upstream-variant-2KB
rs7578993 -- 176,601,903(+) GAACA(C/T)TCTAG upstream-variant-2KB
rs7579043 -- 176,601,753(+) TGTAG(C/G)GTTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1246 Gene

Variant ID Type Subtype PubMed ID
nsv834464 CNV Gain 17160897

Relevant External Links for MIR1246 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1246 Gene

Disorders for MIR1246 Gene

Relevant External Links for MIR1246

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR1246: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1246 Gene

Publications for MIR1246 Gene

  1. The small RNA content of human sperm reveals pseudogene-derived piRNAs complementary to protein-coding genes. (PMID: 25904136) Pantano L. … Vavouri T. (RNA 2015) 67
  2. MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer. (PMID: 25117811) Hasegawa S. … Ishii H. (Br. J. Cancer 2014) 67
  3. MiR-1246 promotes SiHa cervical cancer cell proliferation, invasion, and migration through suppression of its target gene thrombospondin 2. (PMID: 24806621) Chen J. … Long F. (Arch. Gynecol. Obstet. 2014) 67
  4. Hsa-miR-1246, hsa-miR-320a and hsa-miR-196b-5p inhibitors can reduce the cytotoxicity of Ebola virus glycoprotein in vitro. (PMID: 25218824) Sheng M. … Jiang C. (Sci China Life Sci 2014) 67
  5. MicroRNA-1246 enhances migration and invasion through CADM1 in hepatocellular carcinoma. (PMID: 25159494) Sun Z. … Zhao R.C. (BMC Cancer 2014) 67

Products for MIR1246 Gene

Sources for MIR1246 Gene

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