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Aliases for MIR1245B Gene

Subcategory (RNA class) for MIR1245B Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR1245B Gene

  • MicroRNA 1245b 2 3
  • Hsa-Mir-1245b 3

External Ids for MIR1245B Gene

Summaries for MIR1245B Gene

Entrez Gene Summary for MIR1245B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1245B Gene

MIR1245B (MicroRNA 1245b) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1245B Gene

Genomics for MIR1245B Gene

Genomic Location for MIR1245B Gene

Start:
188,978,093 bp from pter
End:
188,978,161 bp from pter
Size:
69 bases
Orientation:
Minus strand

Genomic View for MIR1245B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1245B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1245B Gene

No data available for Regulatory Elements for MIR1245B Gene

Proteins for MIR1245B Gene

Post-translational modifications for MIR1245B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1245B Gene

Domains for MIR1245B Gene

Gene Families for MIR1245B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR1245B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR1245B Gene

Function for MIR1245B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1245B Gene

Localization for MIR1245B Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR1245B Gene

Pathways for MIR1245B Gene

SuperPathways for MIR1245B Gene

No Data Available

Interacting Proteins for MIR1245B Gene

Gene Ontology (GO) - Biological Process for MIR1245B Gene

None

No data available for Pathways by source for MIR1245B Gene

Transcripts for MIR1245B Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1245B Gene

No ASD Table

Relevant External Links for MIR1245B Gene

GeneLoc Exon Structure for
MIR1245B
ECgene alternative splicing isoforms for
MIR1245B

No data available for mRNA/cDNA for MIR1245B Gene

Expression for MIR1245B Gene

No Expression Related Data Available

Orthologs for MIR1245B Gene

No data available for Orthologs and Evolution for MIR1245B Gene

Paralogs for MIR1245B Gene

No data available for Paralogs for MIR1245B Gene

Variants for MIR1245B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1245B Gene

Variant ID Type Subtype PubMed ID
nsv459992 CNV Loss 19166990
nsv875609 CNV Loss 21882294
nsv875610 CNV Loss 21882294
nsv875612 CNV Loss 21882294

Relevant External Links for MIR1245B Gene

HapMap Linkage Disequilibrium report
MIR1245B

No data available for Sequence variations from dbSNP and Humsavar for MIR1245B Gene

Disorders for MIR1245B Gene

No disorders were found for MIR1245B Gene.

No data available for UniProtKB/Swiss-Prot for MIR1245B Gene

Publications for MIR1245B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR1245B Gene

Sources for MIR1245B Gene

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