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Aliases for MIR1245A Gene

Subcategory (RNA class) for MIR1245A Gene


Quality Score for this RNA gene is


Aliases for MIR1245A Gene

  • MicroRNA 1245a 2 3
  • MicroRNA 1245 2 3
  • Hsa-Mir-1245a 3
  • Hsa-Mir-1245 3
  • Mir-1245a 3
  • MIRN1245 3
  • MIR1245 3

External Ids for MIR1245A Gene

Previous HGNC Symbols for MIR1245A Gene

  • MIRN1245
  • MIR1245

Previous GeneCards Identifiers for MIR1245A Gene

  • GC02P189843

Summaries for MIR1245A Gene

Entrez Gene Summary for MIR1245A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1245A Gene

MIR1245A (MicroRNA 1245a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1245A Gene

Genomics for MIR1245A Gene

Genomic Location for MIR1245A Gene

188,978,092 bp from pter
188,978,161 bp from pter
70 bases
Plus strand

Genomic View for MIR1245A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1245A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1245A Gene

No data available for Regulatory Elements for MIR1245A Gene

Proteins for MIR1245A Gene

Post-translational modifications for MIR1245A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1245A Gene

Domains & Families for MIR1245A Gene

Gene Families for MIR1245A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1245A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1245A Gene

Function for MIR1245A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1245A Gene

Localization for MIR1245A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1245A Gene

Pathways & Interactions for MIR1245A Gene

SuperPathways for MIR1245A Gene

No Data Available

Interacting Proteins for MIR1245A Gene

Gene Ontology (GO) - Biological Process for MIR1245A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1245A Gene

Drugs & Compounds for MIR1245A Gene

No Compound Related Data Available

Transcripts for MIR1245A Gene

mRNA/cDNA for MIR1245A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1245A Gene

No ASD Table

Relevant External Links for MIR1245A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1245A Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1245A Gene

Orthologs for MIR1245A Gene

Evolution for MIR1245A Gene

Gene Tree for MIR1245A (if available)
Gene Tree for MIR1245A (if available)

No data available for Orthologs for MIR1245A Gene

Paralogs for MIR1245A Gene

No data available for Paralogs for MIR1245A Gene

Variants for MIR1245A Gene

Relevant External Links for MIR1245A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1245A Gene

Disorders for MIR1245A Gene

Relevant External Links for MIR1245A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR1245A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1245A Gene

Publications for MIR1245A Gene

  1. Up-regulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. (PMID: 22158906) Song L. … Li J. (J Mol Cell Biol 2012) 67
  2. Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions. (PMID: 22491735) Espinoza J.L. … Nakao S. (Haematologica 2012) 67
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 67
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR1245A Gene

Sources for MIR1245A Gene

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