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Aliases for MIR1244-2 Gene

Subcategory (RNA class) for MIR1244-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1244-2 Gene

  • MicroRNA 1244-2 2 3 5
  • Hsa-Mir-1244-2 3

External Ids for MIR1244-2 Gene

Previous GeneCards Identifiers for MIR1244-2 Gene

  • GC05U901430
  • GC12M009393
  • GC05P118314
  • GC12P012267
  • GC12P012111

Summaries for MIR1244-2 Gene

Entrez Gene Summary for MIR1244-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1244-2 Gene

MIR1244-2 (MicroRNA 1244-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1244-2 Gene

Genomics for MIR1244-2 Gene

Regulatory Elements for MIR1244-2 Gene

Enhancers for MIR1244-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F118987 0.5 ENCODE 0.4 +13.8 13794 1.9 HDGF CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CBX5 ZNF207 DTWD2 PTMAP2 MIR1244-2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1244-2 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1244-2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001872904 -786 401

Genomic Location for MIR1244-2 Gene

Chromosome:
5
Start:
118,974,586 bp from pter
End:
118,974,670 bp from pter
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR1244-2 Gene

Genes around MIR1244-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1244-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1244-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1244-2 Gene

Proteins for MIR1244-2 Gene

Post-translational modifications for MIR1244-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1244-2 Gene

Domains & Families for MIR1244-2 Gene

Gene Families for MIR1244-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1244-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1244-2 Gene

Function for MIR1244-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1244-2 Gene

Localization for MIR1244-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1244-2 Gene

Pathways & Interactions for MIR1244-2 Gene

SuperPathways for MIR1244-2 Gene

No Data Available

Interacting Proteins for MIR1244-2 Gene

Gene Ontology (GO) - Biological Process for MIR1244-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1244-2 Gene

Transcripts for MIR1244-2 Gene

mRNA/cDNA for MIR1244-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1244-2 Gene

No ASD Table

Relevant External Links for MIR1244-2 Gene

GeneLoc Exon Structure for
MIR1244-2
ECgene alternative splicing isoforms for
MIR1244-2

Expression for MIR1244-2 Gene

mRNA expression in normal human tissues for MIR1244-2 Gene

genes like me logo Genes that share expression patterns with MIR1244-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1244-2 Gene

Orthologs for MIR1244-2 Gene

Evolution for MIR1244-2 Gene

ENSEMBL:
Gene Tree for MIR1244-2 (if available)
TreeFam:
Gene Tree for MIR1244-2 (if available)

No data available for Orthologs for MIR1244-2 Gene

Paralogs for MIR1244-2 Gene

No data available for Paralogs for MIR1244-2 Gene

Variants for MIR1244-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1244-2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs111741799 -- 118,973,779(+) CGGAT(A/C)ACCGG intron-variant, upstream-variant-2KB
rs111982089 -- 118,973,427(+) CTTGA(A/G)GAGCT intron-variant, upstream-variant-2KB
rs112737380 -- 118,973,782(+) ATCAC(C/T)GGCGT intron-variant, upstream-variant-2KB
rs112788050 -- 118,973,712(+) GCCGC(A/C/G)GACTC intron-variant, upstream-variant-2KB
rs113024749 -- 118,974,474(+) CCTTC(A/G)GAGCG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1244-2 Gene

Variant ID Type Subtype PubMed ID
esv2759117 CNV gain+loss 17122850
esv2759878 CNV gain+loss 17122850
esv3606474 CNV gain 21293372
esv3628601 CNV loss 21293372
esv3628602 CNV loss 21293372
nsv1017548 CNV loss 25217958
nsv1046355 CNV loss 25217958
nsv1051530 CNV gain 25217958
nsv1126310 CNV deletion 24896259
nsv3204 CNV deletion 18451855
nsv428408 CNV gain+loss 18775914
nsv523958 CNV loss 19592680
nsv527404 CNV gain 19592680
nsv528912 CNV loss 19592680
nsv529005 CNV loss 19592680
nsv557355 CNV gain 21841781
nsv834568 CNV loss 17160897
nsv964930 CNV duplication 23825009
nsv973021 CNV duplication 23825009
nsv976579 CNV duplication 23825009
nsv979182 CNV duplication 23825009

Relevant External Links for MIR1244-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1244-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1244-2 Gene

Disorders for MIR1244-2 Gene

Relevant External Links for MIR1244-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1244-2

No disorders were found for MIR1244-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1244-2 Gene

Publications for MIR1244-2 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1244-2 Gene

Sources for MIR1244-2 Gene

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