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Aliases for MIR1244-1 Gene

Subcategory (RNA class) for MIR1244-1 Gene


Quality Score for this RNA gene is


Aliases for MIR1244-1 Gene

  • MicroRNA 1244-1 2 3
  • MicroRNA 1244 2 3
  • PTMA 4 5
  • Prothymosin, Alpha 5
  • Hsa-Mir-1244-1 3
  • Hsa-Mir-1244 3
  • MIRN1244 3
  • MIR1244 3
  • TMSA 4

External Ids for MIR1244-1 Gene

Previous HGNC Symbols for MIR1244-1 Gene

  • MIRN1244
  • MIR1244

Previous GeneCards Identifiers for MIR1244-1 Gene

  • GC05P118313
  • GC02P232580
  • GC12M009397
  • GC12M009239
  • GC02P231713

Summaries for MIR1244-1 Gene

Entrez Gene Summary for MIR1244-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1244-1 Gene

MIR1244-1 (MicroRNA 1244-1) is an RNA Gene, and is affiliated with the miRNA class.

UniProtKB/Swiss-Prot for MIR1244-1 Gene

  • Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1244-1 Gene

Genomics for MIR1244-1 Gene

Regulatory Elements for MIR1244-1 Gene

Enhancers for MIR1244-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F231701 1.5 FANTOM5 Ensembl ENCODE 0.8 -4.9 -4946 1.3 MLX ZFP64 ARID4B DMAP1 ZNF48 ZBTB40 SCRT2 CREM EGR2 THAP11 RPL28P2 MIR1244-1 PTMA GC02M231678
GH02F231679 1.8 FANTOM5 Ensembl ENCODE 0.3 -24.4 -24365 6.5 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 RNU2-22P NPPC COPS7B PTMA GC02M231678 MIR1244-1
GH02F231686 1.6 FANTOM5 Ensembl ENCODE 0.3 -19.4 -19417 1.3 HDGF MLX ARID4B DMAP1 ZNF48 GLIS2 ZNF143 ZNF263 NFYC MXD4 NPPC GC02M231678 MIR1244-1 PTMA
GH02F231685 1.1 FANTOM5 0.3 -20.8 -20793 0.2 PKNOX1 MLX CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 GC02M231678 PTMA MIR1244-1
GH02F231695 0.7 ENCODE 0.4 -10.6 -10550 1.2 SOX13 GATAD2A HLF CEBPB CEBPG HMG20A YY1 RCOR2 CEBPA TCF7 RNU2-22P PTMA MIR1244-1 GC02M231678
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1244-1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1244-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR1244-1 Gene

231,706,895 bp from pter
231,713,541 bp from pter
6,647 bases
Plus strand

Genomic View for MIR1244-1 Gene

Genes around MIR1244-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1244-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1244-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1244-1 Gene

Proteins for MIR1244-1 Gene

  • Protein details for MIR1244-1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Prothymosin alpha
    Protein Accession:
    Secondary Accessions:
    • Q15249
    • Q15592

    Protein attributes for MIR1244-1 Gene

    111 amino acids
    Molecular mass:
    12203 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MIR1244-1 Gene

    Alternative splice isoforms for MIR1244-1 Gene


neXtProt entry for MIR1244-1 Gene

Post-translational modifications for MIR1244-1 Gene

No data available for DME Specific Peptides for MIR1244-1 Gene

Domains & Families for MIR1244-1 Gene

Gene Families for MIR1244-1 Gene

Protein Domains for MIR1244-1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the pro/parathymosin family.
  • Belongs to the pro/parathymosin family.
genes like me logo Genes that share domains with MIR1244-1: view

No data available for Suggested Antigen Peptide Sequences for MIR1244-1 Gene

Function for MIR1244-1 Gene

Molecular function for MIR1244-1 Gene

UniProtKB/Swiss-Prot Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

Gene Ontology (GO) - Molecular Function for MIR1244-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042393 histone binding IEA --
genes like me logo Genes that share ontologies with MIR1244-1: view

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1244-1 Gene

Localization for MIR1244-1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MIR1244-1 Gene

Gene Ontology (GO) - Cellular Components for MIR1244-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0070062 extracellular exosome IDA --
genes like me logo Genes that share ontologies with MIR1244-1: view

No data available for Subcellular locations from COMPARTMENTS for MIR1244-1 Gene

Pathways & Interactions for MIR1244-1 Gene

SuperPathways for MIR1244-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1244-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated TAS --
GO:0043486 histone exchange IEA --
genes like me logo Genes that share ontologies with MIR1244-1: view

No data available for Pathways by source and SIGNOR curated interactions for MIR1244-1 Gene

Transcripts for MIR1244-1 Gene

mRNA/cDNA for MIR1244-1 Gene

(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1244-1 Gene

No ASD Table

Relevant External Links for MIR1244-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1244-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1244-1 Gene

genes like me logo Genes that share expression patterns with MIR1244-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1244-1 Gene

Orthologs for MIR1244-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR1244-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia PTMA 35
  • 99 (a)
-- 35
  • 88 (a)
-- 35
  • 64 (a)
(Bos Taurus)
Mammalia PTMA 35 35
  • 98 (a)
(Mus musculus)
Mammalia Ptma 35
  • 95 (a)
Gm6625 35
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia PTMA 35
  • 72 (a)
(Anolis carolinensis)
Reptilia PTMA 35
  • 91 (a)
Species where no ortholog for MIR1244-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1244-1 Gene

Gene Tree for MIR1244-1 (if available)
Gene Tree for MIR1244-1 (if available)

Paralogs for MIR1244-1 Gene

No data available for Paralogs for MIR1244-1 Gene

Variants for MIR1244-1 Gene

Sequence variations from dbSNP and Humsavar for MIR1244-1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10175813 -- 231,711,859(+) AGCTG(A/G)TAATG intron-variant, upstream-variant-2KB
rs1059834 -- 231,711,939(+) agaag(A/G)ggaag intron-variant, upstream-variant-2KB, reference, missense
rs1060635 -- 231,713,184(+) CTCGG(A/G)TGACC upstream-variant-2KB, utr-variant-3-prime
rs1064719 -- 231,711,934(+) gacga(A/C)gaaga intron-variant, upstream-variant-2KB, reference, missense
rs111878292 -- 231,712,518(+) TGAGG(G/T)GGGTT upstream-variant-2KB, splice-donor-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1244-1 Gene

Variant ID Type Subtype PubMed ID
esv2759117 CNV gain+loss 17122850
esv2759878 CNV gain+loss 17122850
esv3606474 CNV gain 21293372
esv3628601 CNV loss 21293372
esv3628602 CNV loss 21293372
nsv1017548 CNV loss 25217958
nsv1046355 CNV loss 25217958
nsv1051530 CNV gain 25217958
nsv1126310 CNV deletion 24896259
nsv3204 CNV deletion 18451855
nsv428408 CNV gain+loss 18775914
nsv523958 CNV loss 19592680
nsv527404 CNV gain 19592680
nsv528912 CNV loss 19592680
nsv529005 CNV loss 19592680
nsv557355 CNV gain 21841781
nsv834568 CNV loss 17160897
nsv964930 CNV duplication 23825009
nsv973021 CNV duplication 23825009
nsv976579 CNV duplication 23825009
nsv979182 CNV duplication 23825009

Relevant External Links for MIR1244-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1244-1 Gene

Disorders for MIR1244-1 Gene

Relevant External Links for MIR1244-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1244-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1244-1 Gene

Publications for MIR1244-1 Gene

  1. miR-1244/Myocyte Enhancer Factor 2D Regulatory Loop Contributes to the Growth of Lung Carcinoma. (PMID: 26355845) Zhang R. … Li H. (DNA Cell Biol. 2015) 3 64
  2. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 64
  3. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  4. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PMID: 22223895) Bienvenut W.V. … Giglione C. (Mol. Cell Proteomics 2012) 4 64
  5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 4 64

Products for MIR1244-1 Gene

Sources for MIR1244-1 Gene

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