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Aliases for MIR1244-1 Gene

Subcategory (RNA class) for MIR1244-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1244-1 Gene

  • MicroRNA 1244-1 2 3
  • MicroRNA 1244 2 3
  • PTMA 4 5
  • Prothymosin, Alpha 5
  • Hsa-Mir-1244-1 3
  • Hsa-Mir-1244 3
  • MIRN1244 3
  • MIR1244 3
  • TMSA 4

External Ids for MIR1244-1 Gene

Previous HGNC Symbols for MIR1244-1 Gene

  • MIRN1244
  • MIR1244

Previous GeneCards Identifiers for MIR1244-1 Gene

  • GC05P118313
  • GC02P232580
  • GC12M009397
  • GC12M009239
  • GC02P231713

Summaries for MIR1244-1 Gene

Entrez Gene Summary for MIR1244-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1244-1 Gene

MIR1244-1 (MicroRNA 1244-1) is an RNA Gene, and is affiliated with the miRNA class.

UniProtKB/Swiss-Prot for MIR1244-1 Gene

  • Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1244-1 Gene

Genomics for MIR1244-1 Gene

Regulatory Elements for MIR1244-1 Gene

Enhancers for MIR1244-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR1244-1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1244-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR1244-1 Gene

Chromosome:
2
Start:
231,706,895 bp from pter
End:
231,713,541 bp from pter
Size:
6,647 bases
Orientation:
Plus strand

Genomic View for MIR1244-1 Gene

Genes around MIR1244-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1244-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1244-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1244-1 Gene

Proteins for MIR1244-1 Gene

  • Protein details for MIR1244-1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P06454-PTMA_HUMAN
    Recommended name:
    Prothymosin alpha
    Protein Accession:
    P06454
    Secondary Accessions:
    • Q15249
    • Q15592

    Protein attributes for MIR1244-1 Gene

    Size:
    111 amino acids
    Molecular mass:
    12203 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MIR1244-1 Gene

    Alternative splice isoforms for MIR1244-1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MIR1244-1 Gene

Post-translational modifications for MIR1244-1 Gene

No data available for DME Specific Peptides for MIR1244-1 Gene

Domains & Families for MIR1244-1 Gene

Gene Families for MIR1244-1 Gene

Protein Domains for MIR1244-1 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

P06454

UniProtKB/Swiss-Prot:

PTMA_HUMAN :
  • Belongs to the pro/parathymosin family.
Family:
  • Belongs to the pro/parathymosin family.
genes like me logo Genes that share domains with MIR1244-1: view

No data available for Suggested Antigen Peptide Sequences for MIR1244-1 Gene

Function for MIR1244-1 Gene

Molecular function for MIR1244-1 Gene

UniProtKB/Swiss-Prot Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

Gene Ontology (GO) - Molecular Function for MIR1244-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042393 histone binding IEA --
genes like me logo Genes that share ontologies with MIR1244-1: view

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1244-1 Gene

Localization for MIR1244-1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MIR1244-1 Gene

Gene Ontology (GO) - Cellular Components for MIR1244-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus TAS --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0070062 extracellular exosome IDA --
genes like me logo Genes that share ontologies with MIR1244-1: view

No data available for Subcellular locations from COMPARTMENTS for MIR1244-1 Gene

Pathways & Interactions for MIR1244-1 Gene

SuperPathways for MIR1244-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1244-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated TAS --
GO:0043486 histone exchange IEA --
genes like me logo Genes that share ontologies with MIR1244-1: view

No data available for Pathways by source and SIGNOR curated interactions for MIR1244-1 Gene

Drugs & Compounds for MIR1244-1 Gene

No Compound Related Data Available

Transcripts for MIR1244-1 Gene

mRNA/cDNA for MIR1244-1 Gene

(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1244-1 Gene

No ASD Table

Relevant External Links for MIR1244-1 Gene

GeneLoc Exon Structure for
MIR1244-1
ECgene alternative splicing isoforms for
MIR1244-1

Expression for MIR1244-1 Gene

mRNA expression in normal human tissues for MIR1244-1 Gene

genes like me logo Genes that share expression patterns with MIR1244-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1244-1 Gene

Orthologs for MIR1244-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR1244-1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia PTMA 35
  • 98 (a)
OneToMany
PTMA 35
  • 95 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 64 (a)
OneToMany
-- 35
  • 88 (a)
OneToMany
PTMA 35
  • 99 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm6625 35
  • 53 (a)
OneToMany
Ptma 35
  • 95 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia PTMA 35
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia PTMA 35
  • 91 (a)
OneToOne
Species where no ortholog for MIR1244-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1244-1 Gene

ENSEMBL:
Gene Tree for MIR1244-1 (if available)
TreeFam:
Gene Tree for MIR1244-1 (if available)

Paralogs for MIR1244-1 Gene

No data available for Paralogs for MIR1244-1 Gene

Variants for MIR1244-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1244-1 Gene

Variant ID Type Subtype PubMed ID
esv2759117 CNV gain+loss 17122850
esv2759878 CNV gain+loss 17122850
esv3606474 CNV gain 21293372
esv3628601 CNV loss 21293372
esv3628602 CNV loss 21293372
nsv1017548 CNV loss 25217958
nsv1046355 CNV loss 25217958
nsv1051530 CNV gain 25217958
nsv1126310 CNV deletion 24896259
nsv3204 CNV deletion 18451855
nsv428408 CNV gain+loss 18775914
nsv523958 CNV loss 19592680
nsv527404 CNV gain 19592680
nsv528912 CNV loss 19592680
nsv529005 CNV loss 19592680
nsv557355 CNV gain 21841781
nsv834568 CNV loss 17160897
nsv964930 CNV duplication 23825009
nsv973021 CNV duplication 23825009
nsv976579 CNV duplication 23825009
nsv979182 CNV duplication 23825009

Relevant External Links for MIR1244-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1244-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR1244-1 Gene

Disorders for MIR1244-1 Gene

Relevant External Links for MIR1244-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1244-1

No disorders were found for MIR1244-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1244-1 Gene

Publications for MIR1244-1 Gene

  1. miR-1244/Myocyte Enhancer Factor 2D Regulatory Loop Contributes to the Growth of Lung Carcinoma. (PMID: 26355845) Zhang R. … Li H. (DNA Cell Biol. 2015) 3 65
  2. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 65
  3. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  4. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PMID: 22223895) Bienvenut W.V. … Giglione C. (Mol. Cell Proteomics 2012) 4 65
  5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 4 65

Products for MIR1244-1 Gene

Sources for MIR1244-1 Gene

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