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Aliases for MIR124-3 Gene

Subcategory (RNA class) for MIR124-3 Gene


Quality Score for this RNA gene is


Aliases for MIR124-3 Gene

  • MicroRNA 124-3 2 3 5
  • MicroRNA 124a-3 2 3
  • Hsa-Mir-124a-3 3
  • Hsa-Mir-124-3 3
  • Mir-124-3 3
  • MIRN124-3 3
  • MIRN124A3 3

External Ids for MIR124-3 Gene

ORGUL Members for MIR124-3 Gene

Previous HGNC Symbols for MIR124-3 Gene

  • MIRN124A3
  • MIRN124-3

Previous GeneCards Identifiers for MIR124-3 Gene

  • GC20P061284
  • GC20P061812
  • GC20P063179

Summaries for MIR124-3 Gene

Entrez Gene Summary for MIR124-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR124-3 Gene

MIR124-3 (MicroRNA 124-3) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR124-3 Gene

Genomics for MIR124-3 Gene

Genomic Location for MIR124-3 Gene

63,178,500 bp from pter
63,178,586 bp from pter
87 bases
Plus strand

Genomic View for MIR124-3 Gene

Genes around MIR124-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR124-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR124-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR124-3 Gene

No data available for Regulatory Elements for MIR124-3 Gene

Proteins for MIR124-3 Gene

Post-translational modifications for MIR124-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR124-3 Gene

Domains & Families for MIR124-3 Gene

Gene Families for MIR124-3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR124-3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR124-3 Gene

Function for MIR124-3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR124-3 Gene

Localization for MIR124-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR124-3 Gene

Pathways & Interactions for MIR124-3 Gene

SuperPathways for MIR124-3 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR124-3: view

Pathways by source for MIR124-3 Gene

1 KEGG pathway for MIR124-3 Gene

Interacting Proteins for MIR124-3 Gene

Gene Ontology (GO) - Biological Process for MIR124-3 Gene


No data available for SIGNOR curated interactions for MIR124-3 Gene

Drugs & Compounds for MIR124-3 Gene

No Compound Related Data Available

Transcripts for MIR124-3 Gene

mRNA/cDNA for MIR124-3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR124-3 Gene

No ASD Table

Relevant External Links for MIR124-3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR124-3 Gene

mRNA expression in normal human tissues for MIR124-3 Gene

genes like me logo Genes that share expression patterns with MIR124-3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR124-3 Gene

Orthologs for MIR124-3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR124-3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-124b 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-124a-3 36
  • 100 (a)
(Mus musculus)
Mammalia Mir124a-3 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-124a-2 36
  • 81 (a)
(Anolis carolinensis)
Reptilia aca-mir-124a-3 36
  • 79 (a)
(Danio rerio)
Actinopterygii dre-mir-124-2 36
  • 86 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-124-1 36
  • 48 (a)
csa-mir-124-2 36
  • 53 (a)
Species with no ortholog for MIR124-3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR124-3 Gene

Gene Tree for MIR124-3 (if available)
Gene Tree for MIR124-3 (if available)

Paralogs for MIR124-3 Gene

No data available for Paralogs for MIR124-3 Gene

Variants for MIR124-3 Gene

Sequence variations from dbSNP and Humsavar for MIR124-3 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1884338 -- 63,177,378(+) GGCTG(A/C)GTCCG upstream-variant-2KB
rs1884339 -- 63,177,601(+) AGGCA(A/G)CGGCG upstream-variant-2KB
rs1884340 -- 63,177,607(+) CGGCG(A/G)CGGCG upstream-variant-2KB
rs6011652 -- 63,176,610(+) AGGAA(A/G)GAAGC upstream-variant-2KB
rs6011653 -- 63,177,232(+) TGGCT(A/G)GAGGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR124-3 Gene

Variant ID Type Subtype PubMed ID
nsv913073 CNV Loss 21882294
nsv9825 CNV Gain 18304495
dgv4618n71 CNV Loss 21882294
nsv913161 CNV Loss 21882294
dgv68n68 CNV Loss 17160897
nsv913165 CNV Loss 21882294
nsv913166 CNV Loss 21882294
nsv834031 CNV Loss 17160897
dgv519n27 CNV Loss 19166990
dgv4626n71 CNV Loss 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR124-3 Gene

Disorders for MIR124-3 Gene

Relevant External Links for MIR124-3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR124-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR124-3 Gene

Publications for MIR124-3 Gene

  1. miRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell carcinoma aggressive behaviour by targeting CAV1 and FLOT1. (PMID: 26002553) Butz H. … Yousef G.M. (Oncotarget 2015) 3 67
  2. Quantification of plasma microRNAs in a group of healthy smokers, ex-smokers and non-smokers and correlation to biomarkers of tobacco exposure. (PMID: 25598229) Banerjee A. … Minet E. (Biomarkers 2015) 3
  3. MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer. (PMID: 25818238) Taniguchi K. … Akao Y. (Cancer Lett. 2015) 3
  4. Decreased expression of microRNA-124 is an independent unfavorable prognostic factor for patients with breast cancer. (PMID: 25924779) Dong L.L. … Zhang L.M. (Diagn Pathol 2015) 3
  5. Downregulation of rho-associated protein kinase 1 by miR-124 in colorectal cancer. (PMID: 25987767) Xi Z.W. … Chen K.X. (World J. Gastroenterol. 2015) 3

Products for MIR124-3 Gene

Sources for MIR124-3 Gene