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Aliases for MIR1238 Gene

Subcategory (RNA class) for MIR1238 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1238 Gene

  • MicroRNA 1238 2 3 5
  • Hsa-Mir-1238 3
  • MIRN1238 3

External Ids for MIR1238 Gene

Previous HGNC Symbols for MIR1238 Gene

  • MIRN1238

Previous GeneCards Identifiers for MIR1238 Gene

  • GC00U922934
  • GC19P010664

Summaries for MIR1238 Gene

Entrez Gene Summary for MIR1238 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1238 Gene

MIR1238 (MicroRNA 1238) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1238 Gene

Genomics for MIR1238 Gene

Regulatory Elements for MIR1238 Gene

Enhancers for MIR1238 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G010514 1.6 FANTOM5 ENCODE dbSUPER 12 -34.9 -34906 5.2 PKNOX1 FOXA2 SIN3A ZNF2 ZNF48 ZNF121 GLIS2 KLF7 ZNF263 SP3 S1PR5 KRI1 ATG4D ZNF846 LOC100419831 CDKN2D SLC44A2 RNU7-140P MIR1238 ILF3
GH19G010515 1 ENCODE dbSUPER 12 -37.8 -37803 0.2 CTCF SUZ12 TEAD4 KLF17 RBBP5 ZNF2 ZNF121 POLR2A EZH2 SCRT1 ATG4D KRI1 CDKN2D MIR1238 RNU7-140P ILF3 SLC44A2 S1PR5 KEAP1
GH19G010552 1.4 Ensembl ENCODE dbSUPER 0.7 +2.0 2015 5.3 HDGF PKNOX1 AGO1 KLF17 RAD21 GLIS2 SCRT2 FOS ETV6 EGR2 KRI1 CDKN2D SLC44A2 ILF3 QTRT1 ILF3-AS1 MIR1238
GH19G010551 0.4 ENCODE 0.7 -1.0 -1009 0.2 ZEB2 KRI1 MIR1238 RNU7-140P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1238 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1238 Gene

Chromosome:
19
Start:
10,552,122 bp from pter
End:
10,552,204 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR1238 Gene

Genes around MIR1238 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1238 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1238 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1238 Gene

Proteins for MIR1238 Gene

Post-translational modifications for MIR1238 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1238 Gene

Domains & Families for MIR1238 Gene

Gene Families for MIR1238 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1238: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1238 Gene

Function for MIR1238 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1238 Gene

Localization for MIR1238 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1238 Gene

Pathways & Interactions for MIR1238 Gene

SuperPathways for MIR1238 Gene

No Data Available

Interacting Proteins for MIR1238 Gene

Gene Ontology (GO) - Biological Process for MIR1238 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1238 Gene

Drugs & Compounds for MIR1238 Gene

No Compound Related Data Available

Transcripts for MIR1238 Gene

mRNA/cDNA for MIR1238 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1238 Gene

No ASD Table

Relevant External Links for MIR1238 Gene

GeneLoc Exon Structure for
MIR1238
ECgene alternative splicing isoforms for
MIR1238

Expression for MIR1238 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1238 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1238 Gene:

MIR1238
genes like me logo Genes that share expression patterns with MIR1238: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1238 Gene

Orthologs for MIR1238 Gene

Evolution for MIR1238 Gene

ENSEMBL:
Gene Tree for MIR1238 (if available)
TreeFam:
Gene Tree for MIR1238 (if available)

No data available for Orthologs for MIR1238 Gene

Paralogs for MIR1238 Gene

No data available for Paralogs for MIR1238 Gene

Variants for MIR1238 Gene

Sequence variations from dbSNP and Humsavar for MIR1238 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1001239575 -- 10,550,618(+) GGGCC(G/T)CCTCA intron-variant, upstream-variant-2KB
rs1001487489 -- 10,551,174(+) AGATA(A/G)ATCAT intron-variant, upstream-variant-2KB
rs1001587434 -- 10,550,378(+) AAAGC(A/G)CCTCT intron-variant, upstream-variant-2KB
rs1001961637 -- 10,550,985(+) GATTA(A/C/T)GGACA intron-variant, upstream-variant-2KB
rs1003700029 -- 10,552,481(+) GAAAA(A/G)GTGGG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1238 Gene

Variant ID Type Subtype PubMed ID
nsv833744 CNV loss 17160897
nsv833745 CNV loss 17160897

Relevant External Links for MIR1238 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1238

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1238 Gene

Disorders for MIR1238 Gene

Relevant External Links for MIR1238

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1238

No disorders were found for MIR1238 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1238 Gene

Publications for MIR1238 Gene

  1. Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis. (PMID: 27722176) Budak F. … Oral H.B. (J Immunol Res 2016) 3 64
  2. miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer. (PMID: 26189214) Shi X. … Zhang H.T. (Oncotarget 2015) 3 64
  3. Mammalian mirtron genes. (PMID: 17964270) Berezikov E. … Lai E.C. (Mol. Cell 2007) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1238 Gene

Sources for MIR1238 Gene

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