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Aliases for MIR1236 Gene

Subcategory (RNA class) for MIR1236 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1236 Gene

  • MicroRNA 1236 2 3 5
  • Hsa-Mir-1236 3
  • MIRN1236 3

External Ids for MIR1236 Gene

Previous HGNC Symbols for MIR1236 Gene

  • MIRN1236

Previous GeneCards Identifiers for MIR1236 Gene

  • GC00U922986
  • GC06M032034
  • GC06M031924
  • GC06M031712

Summaries for MIR1236 Gene

Entrez Gene Summary for MIR1236 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1236 Gene

MIR1236 (MicroRNA 1236) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are HIV Life Cycle and Formation of HIV elongation complex in the absence of HIV Tat.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1236 Gene

Genomics for MIR1236 Gene

Regulatory Elements for MIR1236 Gene

Enhancers for MIR1236 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G031910 1.2 Ensembl ENCODE 11.5 +45.8 45763 2.0 ARID4B GTF3C2 GLIS2 FOS ZNF263 MXD4 JUNB SSRP1 SMARCA4 GLIS1 SKIV2L C4A LY6G5B VARS HLA-DRB5 LSM2 RNU6-850P HLA-C ATF6B DDX39B
GH06G031861 1.2 ENCODE 10.5 +92.8 92825 4.5 MLX CREB3L1 AGO1 ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 LSM2 LY6G5B MICA PPT2 C4A GTF2H4 DDX39B STK19B LY6G5C PRRT1
GH06G031928 1 ENCODE 11.8 +27.5 27465 1.2 PKNOX1 AGO1 ZFP64 ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF143 ZNF207 SKIV2L LY6G5B ATF6B DDX39B NFKBIL1 LSM2 PPT2 MIR1236 TCF19 STK19
GH06G032090 0.2 dbSUPER 10 -133.9 -133944 0.4 TNXB ATF6B FKBPL PPT2 PRRT1 EGFL8 RNF5 AGPAT1 SKIV2L MIR1236
GH06G031952 0.9 ENCODE 0.7 +4.4 4402 0.2 ELF3 PKNOX1 RB1 ARID4B DMAP1 ZNF2 RAD21 RARA RFX5 ZNF143 MIR1236 CFB
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1236 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1236 Gene

Chromosome:
6
Start:
31,956,839 bp from pter
End:
31,956,940 bp from pter
Size:
102 bases
Orientation:
Minus strand

Genomic View for MIR1236 Gene

Genes around MIR1236 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1236 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1236 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for MIR1236 Gene

Post-translational modifications for MIR1236 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1236 Gene

Domains & Families for MIR1236 Gene

Gene Families for MIR1236 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1236: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1236 Gene

Function for MIR1236 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1236 Gene

Localization for MIR1236 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1236 Gene

Pathways & Interactions for MIR1236 Gene

genes like me logo Genes that share pathways with MIR1236: view

Interacting Proteins for MIR1236 Gene

Gene Ontology (GO) - Biological Process for MIR1236 Gene

None

No data available for SIGNOR curated interactions for MIR1236 Gene

Drugs & Compounds for MIR1236 Gene

No Compound Related Data Available

Transcripts for MIR1236 Gene

mRNA/cDNA for MIR1236 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1236 Gene

No ASD Table

Relevant External Links for MIR1236 Gene

GeneLoc Exon Structure for
MIR1236
ECgene alternative splicing isoforms for
MIR1236

Expression for MIR1236 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1236 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1236 Gene:

MIR1236
genes like me logo Genes that share expression patterns with MIR1236: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1236 Gene

Orthologs for MIR1236 Gene

Evolution for MIR1236 Gene

ENSEMBL:
Gene Tree for MIR1236 (if available)
TreeFam:
Gene Tree for MIR1236 (if available)

No data available for Orthologs for MIR1236 Gene

Paralogs for MIR1236 Gene

No data available for Paralogs for MIR1236 Gene

Variants for MIR1236 Gene

Sequence variations from dbSNP and Humsavar for MIR1236 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs17201466 Likely benign 31,958,823(+) AGCAA(C/T)GCAAA intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs182142262 Uncertain significance 31,958,913(+) CGGGG(G/T)CCCCA upstream-variant-2KB, utr-variant-5-prime
rs886061298 Uncertain significance 31,958,920(+) CCCAC(A/G)GTCTC upstream-variant-2KB, utr-variant-5-prime
rs886061299 Uncertain significance 31,958,924(+) CGGTC(C/T)CCGGC upstream-variant-2KB, utr-variant-5-prime
rs1003248402 -- 31,957,432(+) GCTTA(C/G)AGTCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1236 Gene

Variant ID Type Subtype PubMed ID
dgv10403n54 CNV loss 21841781
dgv10404n54 CNV loss 21841781
dgv10463n54 CNV loss 21841781
esv2759415 CNV gain+loss 17122850
nsv1073969 CNV deletion 25765185
nsv1112900 CNV deletion 24896259
nsv1126749 CNV deletion 24896259
nsv428141 CNV gain+loss 18775914
nsv830628 CNV loss 17160897

Relevant External Links for MIR1236 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1236

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1236 Gene

Disorders for MIR1236 Gene

Relevant External Links for MIR1236

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1236

No disorders were found for MIR1236 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1236 Gene

Publications for MIR1236 Gene

  1. miR-1236-3p represses the cell migration and invasion abilities by targeting ZEB1 in high-grade serous ovarian carcinoma. (PMID: 24573236) Wang Y. … Kong B. (Oncol. Rep. 2014) 3 64
  2. miRNA-1236 inhibits HIV-1 infection of monocytes by repressing translation of cellular factor VprBP. (PMID: 24932481) Ma L. … Wang J.H. (PLoS ONE 2014) 3 64
  3. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles R.A. … Easton D.F. (Nat. Genet. 2013) 3 64
  4. Mirtron microRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis. (PMID: 22223733) Jones D. … Min W. (Arterioscler. Thromb. Vasc. Biol. 2012) 3 64
  5. Mammalian mirtron genes. (PMID: 17964270) Berezikov E. … Lai E.C. (Mol. Cell 2007) 3 64

Products for MIR1236 Gene

Sources for MIR1236 Gene

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