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Aliases for MIR1234 Gene

Subcategory (RNA class) for MIR1234 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1234 Gene

  • MicroRNA 1234 2 3 5
  • Hsa-Mir-1234 3
  • MIRN1234 3

External Ids for MIR1234 Gene

Previous HGNC Symbols for MIR1234 Gene

  • MIRN1234

Previous GeneCards Identifiers for MIR1234 Gene

  • GC00U923039
  • GC08M145598
  • GC08M145625

Summaries for MIR1234 Gene

Entrez Gene Summary for MIR1234 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1234 Gene

MIR1234 (MicroRNA 1234) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1234 Gene

Genomics for MIR1234 Gene

Regulatory Elements for MIR1234 Gene

Enhancers for MIR1234 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G144396 0.7 ENCODE 0.7 +3.1 3095 0.2 HDGF KLF1 AGO1 SP2 REST SP1 POLR2A KLF9 ZBTB33 IRF1 CPSF1 MIR1234 MIR939
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1234 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1234 Gene

Chromosome:
8
Start:
144,400,086 bp from pter
End:
144,400,165 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR1234 Gene

Genes around MIR1234 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1234 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1234 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1234 Gene

Proteins for MIR1234 Gene

Post-translational modifications for MIR1234 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1234 Gene

Domains & Families for MIR1234 Gene

Gene Families for MIR1234 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1234: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1234 Gene

Function for MIR1234 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1234 Gene

Localization for MIR1234 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1234 Gene

Drugs & Compounds for MIR1234 Gene

No Compound Related Data Available

Transcripts for MIR1234 Gene

mRNA/cDNA for MIR1234 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1234 Gene

No ASD Table

Relevant External Links for MIR1234 Gene

GeneLoc Exon Structure for
MIR1234
ECgene alternative splicing isoforms for
MIR1234

Expression for MIR1234 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1234 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1234 Gene:

MIR1234
genes like me logo Genes that share expression patterns with MIR1234: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1234 Gene

Orthologs for MIR1234 Gene

Evolution for MIR1234 Gene

ENSEMBL:
Gene Tree for MIR1234 (if available)
TreeFam:
Gene Tree for MIR1234 (if available)

No data available for Orthologs for MIR1234 Gene

Paralogs for MIR1234 Gene

No data available for Paralogs for MIR1234 Gene

Variants for MIR1234 Gene

Sequence variations from dbSNP and Humsavar for MIR1234 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000079849 -- 144,400,198(+) TGAGG(C/G)TGTTG downstream-variant-500B, upstream-variant-2KB, reference, missense
rs1001460151 -- 144,400,042(+) AAGGT(A/G)GCCTG downstream-variant-500B, upstream-variant-2KB, reference, synonymous-codon
rs1002854810 -- 144,400,890(+) CCCAC(C/G)CCAGC intron-variant, upstream-variant-2KB
rs1003544905 -- 144,401,132(+) AACAC(C/T)TGGGG intron-variant, upstream-variant-2KB
rs1004581928 -- 144,401,726(+) TCACC(C/T)CATCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1234 Gene

Variant ID Type Subtype PubMed ID
dgv3080n100 CNV gain 25217958
dgv3081n100 CNV gain 25217958
esv2422420 CNV duplication 17116639
esv2758673 CNV gain 17122850
esv3582465 CNV loss 25503493
nsv1064415 CNV gain 25217958
nsv1118744 CNV deletion 24896259
nsv509644 CNV insertion 20534489
nsv827852 CNV gain 20364138
nsv833332 CNV loss 17160897
nsv833333 CNV loss 17160897
nsv9489 CNV gain 18304495
nsv952096 CNV deletion 24416366

Relevant External Links for MIR1234 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1234

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1234 Gene

Disorders for MIR1234 Gene

Relevant External Links for MIR1234

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1234

No disorders were found for MIR1234 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1234 Gene

Publications for MIR1234 Gene

  1. Expression of microRNA-1234 related signal transducer and activator of transcription 3 in patients with diffuse large B-cell lymphoma of activated B-cell like type from high and low infectious disease areas. (PMID: 23841503) HAPgfeldt T. … Moshfegh A. (Leuk. Lymphoma 2013) 3 64
  2. Mammalian mirtron genes. (PMID: 17964270) Berezikov E. … Lai E.C. (Mol. Cell 2007) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1234 Gene

Sources for MIR1234 Gene

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