Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1231 Gene

Subcategory (RNA class) for MIR1231 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1231 Gene

  • MicroRNA 1231 2 3 5
  • Hsa-Mir-1231 3
  • MIRN1231 3

External Ids for MIR1231 Gene

Previous HGNC Symbols for MIR1231 Gene

  • MIRN1231

Previous GeneCards Identifiers for MIR1231 Gene

  • GC00U923126
  • GC01P200046

Summaries for MIR1231 Gene

Entrez Gene Summary for MIR1231 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1231 Gene

MIR1231 (MicroRNA 1231) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1231 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1231 Gene

Genomics for MIR1231 Gene

GeneHancer (GH) Regulatory Elements for MIR1231 Gene

Promoters and enhancers for MIR1231 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I201806 Enhancer 0.4 dbSUPER 550.8 -1.0 -991 2 ZSCAN4 NR2C1 ZBTB12 MIR1231 GC01P201809 SHISA4 TIMM17A IPO9-AS1 ENSG00000235121 NAV1
GH01I201709 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.2 -95.3 -95269 8.7 HDGF PKNOX1 NEUROD1 SIN3A ZNF2 ZBTB7B ZNF143 ZNF548 FOS KLF13 NAV1 MIR1231 RPS27P8 ENSG00000236390 CSRP1 ENSG00000224536 PHLDA3 ENSG00000224818 ARL8A MIR5191
GH01I201747 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.2 -57.7 -57683 7.8 LEF1 PKNOX1 JUN CEBPG ZIC2 ZNF121 GATA3 ZNF316 POLR2A NR2F6 NAV1 MIR1231 CSRP1 ENSG00000224536 ENSG00000236390 IPO9 ENSG00000235121 IPO9-AS1
GH01I201772 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 11.9 -34.6 -34639 3.9 JUND JUN ZNF512 ZKSCAN8 NAV1 MIR1231 ENSG00000235121 RNU6-501P CSRP1 ENSG00000236390 ENSG00000224536 IPO9 IPO9-AS1
GH01I201744 Enhancer 0.7 ENCODE dbSUPER 11.2 -63.3 -63306 1.4 ZFP3 BCL6B NFYB ZFP36 FOS MIR1231 ENSG00000236390 CSRP1 ENSG00000224536 ENSG00000235121 IPO9-AS1 NAV1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1231 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1231 Gene

Genomic Locations for MIR1231 Gene
chr1:201,808,611-201,808,702
(GRCh38/hg38)
Size:
92 bases
Orientation:
Plus strand
chr1:201,777,739-201,777,830
(GRCh37/hg19)

Genomic View for MIR1231 Gene

Genes around MIR1231 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1231 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1231 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1231 Gene

Proteins for MIR1231 Gene

Post-translational modifications for MIR1231 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1231 Gene

Domains & Families for MIR1231 Gene

Gene Families for MIR1231 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1231: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1231 Gene

Function for MIR1231 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1231 Gene

Localization for MIR1231 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1231 Gene

Pathways & Interactions for MIR1231 Gene

SuperPathways for MIR1231 Gene

No Data Available

Interacting Proteins for MIR1231 Gene

Gene Ontology (GO) - Biological Process for MIR1231 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1231 Gene

Drugs & Compounds for MIR1231 Gene

No Compound Related Data Available

Transcripts for MIR1231 Gene

mRNA/cDNA for MIR1231 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1231 Gene

No ASD Table

Relevant External Links for MIR1231 Gene

GeneLoc Exon Structure for
MIR1231
ECgene alternative splicing isoforms for
MIR1231

Expression for MIR1231 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1231 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1231 Gene:

MIR1231
genes like me logo Genes that share expression patterns with MIR1231: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1231 Gene

Orthologs for MIR1231 Gene

Evolution for MIR1231 Gene

ENSEMBL:
Gene Tree for MIR1231 (if available)
TreeFam:
Gene Tree for MIR1231 (if available)

No data available for Orthologs for MIR1231 Gene

Paralogs for MIR1231 Gene

No data available for Paralogs for MIR1231 Gene

Variants for MIR1231 Gene

Sequence variations from dbSNP and Humsavar for MIR1231 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000735841 -- 201,806,852(+) C/T upstream_transcript_variant
rs1001104281 -- 201,807,178(+) A/G upstream_transcript_variant
rs1002225110 -- 201,807,822(+) T/C upstream_transcript_variant
rs1002277450 -- 201,808,106(+) A/C upstream_transcript_variant
rs1003743072 -- 201,806,625(+) G/A/C upstream_transcript_variant

Additional Variant Information for MIR1231 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1231

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1231 Gene

Disorders for MIR1231 Gene

Additional Disease Information for MIR1231

No disorders were found for MIR1231 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1231 Gene

Publications for MIR1231 Gene

  1. Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA. (PMID: 24835118) Kohno T … Chayama K (Journal of viral hepatitis 2014) 3 58
  2. A miR-1231 binding site polymorphism in the 3'UTR of IFNAR1 is associated with hepatocellular carcinoma susceptibility. (PMID: 22824466) Zhou C … Zhang J (Gene 2012) 3 58
  3. Mammalian mirtron genes. (PMID: 17964270) Berezikov E … Lai EC (Molecular cell 2007) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1231 Gene

Sources for MIR1231 Gene

Content
Loading form....