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Aliases for MIR1228 Gene

Subcategory (RNA class) for MIR1228 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1228 Gene

  • MicroRNA 1228 2 3
  • Hsa-Mir-1228 3
  • Mir-1228 3
  • MIRN1228 3

External Ids for MIR1228 Gene

Previous HGNC Symbols for MIR1228 Gene

  • MIRN1228

Previous GeneCards Identifiers for MIR1228 Gene

  • GC00U922937
  • GC12P055876
  • GC12P057588

Summaries for MIR1228 Gene

Entrez Gene Summary for MIR1228 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1228 Gene

MIR1228 (MicroRNA 1228) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1228 Gene

Genomics for MIR1228 Gene

Genomic Location for MIR1228 Gene

Chromosome:
12
Start:
57,194,504 bp from pter
End:
57,194,576 bp from pter
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR1228 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1228 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1228 Gene

No data available for Regulatory Elements for MIR1228 Gene

Proteins for MIR1228 Gene

Post-translational modifications for MIR1228 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1228 Gene

Domains & Families for MIR1228 Gene

Gene Families for MIR1228 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1228: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1228 Gene

Function for MIR1228 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1228 Gene

Localization for MIR1228 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1228 Gene

Pathways & Interactions for MIR1228 Gene

SuperPathways for MIR1228 Gene

No Data Available

Interacting Proteins for MIR1228 Gene

Gene Ontology (GO) - Biological Process for MIR1228 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1228 Gene

Drugs & Compounds for MIR1228 Gene

No Compound Related Data Available

Transcripts for MIR1228 Gene

mRNA/cDNA for MIR1228 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1228 Gene

No ASD Table

Relevant External Links for MIR1228 Gene

GeneLoc Exon Structure for
MIR1228
ECgene alternative splicing isoforms for
MIR1228

Expression for MIR1228 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1228 Gene

Orthologs for MIR1228 Gene

Evolution for MIR1228 Gene

ENSEMBL:
Gene Tree for MIR1228 (if available)
TreeFam:
Gene Tree for MIR1228 (if available)

No data available for Orthologs for MIR1228 Gene

Paralogs for MIR1228 Gene

No data available for Paralogs for MIR1228 Gene

Variants for MIR1228 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1228 Gene

Variant ID Type Subtype PubMed ID
dgv96n21 CNV Loss 19592680
dgv1428n71 CNV Loss 21882294
nsv519293 CNV Loss 19592680

Relevant External Links for MIR1228 Gene

HapMap Linkage Disequilibrium report
MIR1228

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR1228 Gene

Disorders for MIR1228 Gene

Relevant External Links for MIR1228

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1228
genes like me logo Genes that share disorders with MIR1228: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1228 Gene

Publications for MIR1228 Gene

  1. miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop. (PMID: 25422913) Zhang Y. … Tang H. (Br. J. Cancer 2015) 67
  2. Human miR-1228 as a stable endogenous control for the quantification of circulating microRNAs in cancer patients. (PMID: 24488924) Hu J. … Wang J. (Int. J. Cancer 2014) 67
  3. Restoration of miR-1228* expression suppresses epithelial-mesenchymal transition in gastric cancer. (PMID: 23554909) Jia L. … Cai J. (PLoS ONE 2013) 67
  4. Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts. (PMID: 23362149) Lisse T.S. … Hewison M. (J. Bone Miner. Res. 2013) 67
  5. miR-1228 prevents cellular apoptosis through targeting of MOAP1 protein. (PMID: 22434376) Yan B. … Zhao J.L. (Apoptosis 2012) 67

Products for MIR1228 Gene

Sources for MIR1228 Gene

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