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Aliases for MIR1226 Gene

Subcategory (RNA class) for MIR1226 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1226 Gene

  • MicroRNA 1226 2 3 5
  • Hsa-Mir-1226 3
  • Mir-1226 3
  • MIRN1226 3

External Ids for MIR1226 Gene

Previous HGNC Symbols for MIR1226 Gene

  • MIRN1226

Previous GeneCards Identifiers for MIR1226 Gene

  • GC00U922868
  • GC03P047868
  • GC03P047891

Summaries for MIR1226 Gene

Entrez Gene Summary for MIR1226 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1226 Gene

MIR1226 (MicroRNA 1226) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1226 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1226 Gene

Genomics for MIR1226 Gene

Regulatory Elements for MIR1226 Gene

Enhancers for MIR1226 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H047824 1.1 ENCODE 13.1 -24.3 -24276 2 HDGF ARNT ARID4B SIN3A DMAP1 YY1 CBX5 ZNF207 ZNF143 DEK DHX30 FCF1P2 ZNF589 SETD2 PTPN23 MIR1226 MAP4 BOLA2P2 ELP6 ENSG00000260236
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1226 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1226 Gene

Chromosome:
3
Start:
47,849,555 bp from pter
End:
47,849,629 bp from pter
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR1226 Gene

Genes around MIR1226 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1226 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1226 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1226 Gene

Proteins for MIR1226 Gene

Post-translational modifications for MIR1226 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1226 Gene

Domains & Families for MIR1226 Gene

Gene Families for MIR1226 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1226: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1226 Gene

Function for MIR1226 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1226
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1226 Gene

Localization for MIR1226 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1226 Gene

Pathways & Interactions for MIR1226 Gene

SuperPathways for MIR1226 Gene

No Data Available

Interacting Proteins for MIR1226 Gene

Gene Ontology (GO) - Biological Process for MIR1226 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1226 Gene

Drugs & Compounds for MIR1226 Gene

No Compound Related Data Available

Transcripts for MIR1226 Gene

mRNA/cDNA for MIR1226 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1226
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1226 Gene

No ASD Table

Relevant External Links for MIR1226 Gene

GeneLoc Exon Structure for
MIR1226
ECgene alternative splicing isoforms for
MIR1226

Expression for MIR1226 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1226 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1226 Gene:

MIR1226
genes like me logo Genes that share expression patterns with MIR1226: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1226 Gene

Orthologs for MIR1226 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1226 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1226 34
  • 100 (a)
OneToOne
Species where no ortholog for MIR1226 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1226 Gene

ENSEMBL:
Gene Tree for MIR1226 (if available)
TreeFam:
Gene Tree for MIR1226 (if available)

Paralogs for MIR1226 Gene

No data available for Paralogs for MIR1226 Gene

Variants for MIR1226 Gene

Sequence variations from dbSNP and Humsavar for MIR1226 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs753242774 Pathogenic 47,848,237(+) GGGGC(A/C/T)GGGCG upstream-variant-2KB, reference, synonymous-codon
rs1000322488 -- 47,847,671(+) TGTTT(A/G)TCTGC intron-variant, upstream-variant-2KB
rs1000388541 -- 47,848,865(+) TCTGA(G/T)GGGGC intron-variant, upstream-variant-2KB
rs1002179549 -- 47,847,833(+) CCTCC(A/G)GTTGG upstream-variant-2KB, reference, synonymous-codon
rs1008582556 -- 47,847,710(+) CCTTG(A/C)CCTGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1226 Gene

Variant ID Type Subtype PubMed ID
nsv1006560 CNV gain 25217958
nsv508916 CNV insertion 20534489
nsv834679 CNV loss 17160897

Relevant External Links for MIR1226 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1226

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1226 Gene

Disorders for MIR1226 Gene

Relevant External Links for MIR1226

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1226

No disorders were found for MIR1226 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1226 Gene

Publications for MIR1226 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. miR-1226 targets expression of the mucin 1 oncoprotein and induces cell death. (PMID: 20514397) Jin C … Kufe D (International journal of oncology 2010) 3 60
  3. Mammalian mirtron genes. (PMID: 17964270) Berezikov E … Lai EC (Molecular cell 2007) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1226 Gene

Sources for MIR1226 Gene

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