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Aliases for MIR1224 Gene

Subcategory (RNA class) for MIR1224 Gene


Quality Score for this RNA gene is


Aliases for MIR1224 Gene

  • MicroRNA 1224 2 3 5
  • Hsa-Mir-1224 3
  • Mir-1224 3
  • MIRN1224 3

External Ids for MIR1224 Gene

Previous HGNC Symbols for MIR1224 Gene

  • MIRN1224

Previous GeneCards Identifiers for MIR1224 Gene

  • GC03U901145
  • GC03P185443
  • GC03P183959

Summaries for MIR1224 Gene

Entrez Gene Summary for MIR1224 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1224 Gene

MIR1224 (MicroRNA 1224) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1224 Gene

Genomics for MIR1224 Gene

Regulatory Elements for MIR1224 Gene

Enhancers for MIR1224 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR1224 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1224 Gene

184,241,405 bp from pter
184,241,489 bp from pter
85 bases
Plus strand

Genomic View for MIR1224 Gene

Genes around MIR1224 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1224 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1224 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1224 Gene

Proteins for MIR1224 Gene

Post-translational modifications for MIR1224 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1224 Gene

Domains & Families for MIR1224 Gene

Gene Families for MIR1224 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1224: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1224 Gene

Function for MIR1224 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1224 Gene

Localization for MIR1224 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1224 Gene

Pathways & Interactions for MIR1224 Gene

SuperPathways for MIR1224 Gene

No Data Available

Interacting Proteins for MIR1224 Gene

Gene Ontology (GO) - Biological Process for MIR1224 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1224 Gene

Drugs & Compounds for MIR1224 Gene

No Compound Related Data Available

Transcripts for MIR1224 Gene

mRNA/cDNA for MIR1224 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1224 Gene

No ASD Table

Relevant External Links for MIR1224 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1224 Gene

mRNA expression in normal human tissues for MIR1224 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1224 Gene:

genes like me logo Genes that share expression patterns with MIR1224: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1224 Gene

Orthologs for MIR1224 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1224 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-1224 35
  • 92 (a)
(Canis familiaris)
Mammalia -- 35
  • 73 (a)
(Mus musculus)
Mammalia Mir1224 35
  • 81 (a)
(Pan troglodytes)
Mammalia ptr-mir-1224 35
  • 100 (a)
Species where no ortholog for MIR1224 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1224 Gene

Gene Tree for MIR1224 (if available)
Gene Tree for MIR1224 (if available)

Paralogs for MIR1224 Gene

No data available for Paralogs for MIR1224 Gene

Variants for MIR1224 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1224 Gene

Variant ID Type Subtype PubMed ID
nsv528639 CNV loss 19592680
nsv592666 CNV loss 21841781
nsv829812 CNV loss 17160897

Relevant External Links for MIR1224 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR1224 Gene

Disorders for MIR1224 Gene

Relevant External Links for MIR1224

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1224 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1224 Gene

Publications for MIR1224 Gene

  1. MiR-1224-5p acts as a tumor suppressor by targeting CREB1 in malignant gliomas. (PMID: 25648114) Qian J. … You Y.P. (Mol. Cell. Biochem. 2015) 3 65
  2. A mega-analysis of genome-wide association studies for major depressive disorder. (PMID: 22472876) . … Sullivan P.F. (Mol. Psychiatry 2013) 3 65
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 65
  4. Mammalian mirtron genes. (PMID: 17964270) Berezikov E. … Lai E.C. (Mol. Cell 2007) 3 65
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65

Products for MIR1224 Gene

Sources for MIR1224 Gene

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