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Aliases for MIR1208 Gene

Subcategory (RNA class) for MIR1208 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1208 Gene

  • MicroRNA 1208 2 3 5
  • Hsa-Mir-1208 3
  • MIRN1208 3

External Ids for MIR1208 Gene

Previous HGNC Symbols for MIR1208 Gene

  • MIRN1208

Previous GeneCards Identifiers for MIR1208 Gene

  • GC00U923079
  • GC08P129232
  • GC08P129162

Summaries for MIR1208 Gene

Entrez Gene Summary for MIR1208 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1208 Gene

MIR1208 (MicroRNA 1208) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1208 Gene

Genomics for MIR1208 Gene

Regulatory Elements for MIR1208 Gene

Enhancers for MIR1208 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G128171 2.1 FANTOM5 Ensembl ENCODE dbSUPER 11.1 +26.3 26268 9.3 CREB3L1 YBX1 FEZF1 DMAP1 YY1 ZNF548 NFYC PPARGC1A MEF2D GLIS1 MIR1208 MIR1207 CASC11 MYC RNU4-25P GC08P128172 GC08P128221
GH08G128181 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.9 +33.9 33920 5.1 HDGF FOXA2 MLX ZFP64 ARID4B YBX1 DMAP1 ZBTB7B SLC30A9 ZNF766 MIR1208 MIR1207 CASC11 MYC RNU1-106P TMEM75 RNU4-25P GC08P128172 GC08P128221
GH08G128045 2 FANTOM5 Ensembl ENCODE dbSUPER 8.9 -101.8 -101772 6.2 HNRNPUL1 HDGF PKNOX1 ARNT SIN3A ZNF766 ZNF143 FOS JUNB REST RNU1-106P RNU4-25P MIR1205 TMEM75 MIR1208 MIR1207
GH08G128032 1.9 FANTOM5 Ensembl ENCODE dbSUPER 9.1 -115.7 -115703 3.5 HDGF PKNOX1 ATF1 FOXA2 SIN3A ZBTB7B ELK1 FOS CAVIN1 REST RNU4-25P RNU1-106P TMEM75 MIR1208 MIR1207
GH08G128076 1.4 Ensembl ENCODE dbSUPER 9.7 -72.8 -72789 2.5 PKNOX1 BMI1 NFXL1 FOS RELB IKZF2 CREM CBFB USF2 JUNB MIR1207 RNU4-25P MIR1208
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1208 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1208 Gene

Chromosome:
8
Start:
128,150,116 bp from pter
End:
128,150,188 bp from pter
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR1208 Gene

Genes around MIR1208 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1208 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1208 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1208 Gene

Proteins for MIR1208 Gene

Post-translational modifications for MIR1208 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1208 Gene

Domains & Families for MIR1208 Gene

Gene Families for MIR1208 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1208: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1208 Gene

Function for MIR1208 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1208 Gene

Localization for MIR1208 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1208 Gene

Pathways & Interactions for MIR1208 Gene

SuperPathways for MIR1208 Gene

No Data Available

Interacting Proteins for MIR1208 Gene

Gene Ontology (GO) - Biological Process for MIR1208 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1208 Gene

Drugs & Compounds for MIR1208 Gene

No Compound Related Data Available

Transcripts for MIR1208 Gene

mRNA/cDNA for MIR1208 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1208 Gene

No ASD Table

Relevant External Links for MIR1208 Gene

GeneLoc Exon Structure for
MIR1208
ECgene alternative splicing isoforms for
MIR1208

Expression for MIR1208 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1208 Gene:

MIR1208
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1208 Gene

Orthologs for MIR1208 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1208 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1208 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR1208 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1208 Gene

ENSEMBL:
Gene Tree for MIR1208 (if available)
TreeFam:
Gene Tree for MIR1208 (if available)

Paralogs for MIR1208 Gene

No data available for Paralogs for MIR1208 Gene

Variants for MIR1208 Gene

Sequence variations from dbSNP and Humsavar for MIR1208 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001489941 -- 128,149,416(+) GTTCA(A/G)AGAAA upstream-variant-2KB
rs1001556399 -- 128,148,830(+) CATCC(C/G)TACCT upstream-variant-2KB
rs1002389815 -- 128,150,550(+) ACCAG(A/T)TGAAA downstream-variant-500B
rs1002586314 -- 128,148,946(+) TCCAC(A/G)ATTTT upstream-variant-2KB
rs1003069617 -- 128,149,188(+) CACAG(A/G)CTGGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1208 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855

Relevant External Links for MIR1208 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1208

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1208 Gene

Disorders for MIR1208 Gene

Relevant External Links for MIR1208

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1208

No disorders were found for MIR1208 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1208 Gene

Publications for MIR1208 Gene

  1. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin B.M. … Amundadottir L.T. (Nat. Genet. 2014) 3 64
  2. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 3 64
  3. Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. (PMID: 23042114) Hirota T. … Tamari M. (Nat. Genet. 2012) 3 64
  4. The identification of microRNAs in a genomically unstable region of human chromosome 8q24. (PMID: 18314482) Huppi K. … Caplen N.J. (Mol. Cancer Res. 2008) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1208 Gene

Sources for MIR1208 Gene

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