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Aliases for MIR1208 Gene

Subcategory (RNA class) for MIR1208 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1208 Gene

  • MicroRNA 1208 2 3
  • Hsa-Mir-1208 3
  • MIRN1208 3

External Ids for MIR1208 Gene

Previous HGNC Symbols for MIR1208 Gene

  • MIRN1208

Previous GeneCards Identifiers for MIR1208 Gene

  • GC00U923079
  • GC08P129232
  • GC08P129162

Summaries for MIR1208 Gene

Entrez Gene Summary for MIR1208 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1208 Gene

MIR1208 (MicroRNA 1208) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1208 include atopic dermatitis.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1208 Gene

Genomics for MIR1208 Gene

Genomic Location for MIR1208 Gene

Start:
128,150,116 bp from pter
End:
128,150,188 bp from pter
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR1208 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1208 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1208 Gene

No data available for Regulatory Elements for MIR1208 Gene

Proteins for MIR1208 Gene

Post-translational modifications for MIR1208 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1208 Gene

Domains for MIR1208 Gene

Gene Families for MIR1208 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1208: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1208 Gene

Function for MIR1208 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1208 Gene

Localization for MIR1208 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1208 Gene

Pathways for MIR1208 Gene

SuperPathways for MIR1208 Gene

No Data Available

Interacting Proteins for MIR1208 Gene

Gene Ontology (GO) - Biological Process for MIR1208 Gene

None

No data available for Pathways by source for MIR1208 Gene

Transcripts for MIR1208 Gene

mRNA/cDNA for MIR1208 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1208 Gene

No ASD Table

Relevant External Links for MIR1208 Gene

GeneLoc Exon Structure for
MIR1208
ECgene alternative splicing isoforms for
MIR1208

Expression for MIR1208 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR1208 Gene

Orthologs for MIR1208 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1208 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1208 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR1208:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1208 Gene

ENSEMBL:
Gene Tree for MIR1208 (if available)
TreeFam:
Gene Tree for MIR1208 (if available)

Paralogs for MIR1208 Gene

No data available for Paralogs for MIR1208 Gene

Variants for MIR1208 Gene

Sequence variations from dbSNP and Humsavar for MIR1208 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1499371 -- 128,150,005(-) GATCC(A/G)CCAGT upstream-variant-2KB
rs2058885 -- 128,148,409(+) TTTTC(A/T)CCCAT upstream-variant-2KB
rs2648841 -- 128,150,187(-) CCCCC(A/C/T)ACCAC nc-transcript-variant
rs2648842 -- 128,148,254(-) TGCTC(C/T)GAAGG upstream-variant-2KB
rs7814495 -- 128,149,207(+) AACCA(C/G)ATGAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1208 Gene

Variant ID Type Subtype PubMed ID
nsv7419 OTHER Inversion 18451855
nsv499795 OTHER Inversion 21111241

Relevant External Links for MIR1208 Gene

HapMap Linkage Disequilibrium report
MIR1208

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR1208 Gene

Disorders for MIR1208 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR1208 Gene including...

Search for MIR1208 Gene in MalaCards »
genes like me logo Genes that share disorders with MIR1208: view

No data available for UniProtKB/Swiss-Prot for MIR1208 Gene

Publications for MIR1208 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The identification of microRNAs in a genomically unstable region of human chromosome 8q24. (PMID: 18314482) Huppi K. … Caplen N.J. (Mol. Cancer Res. 2008) 3
  3. Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. (PMID: 23042114) Hirota T. … Tamari M. (Nat. Genet. 2012) 3
  4. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 3

Products for MIR1208 Gene

Sources for MIR1208 Gene

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