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Aliases for MIR1207 Gene

Subcategory (RNA class) for MIR1207 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1207 Gene

  • MicroRNA 1207 2 3 5
  • Hsa-Mir-1207 3
  • MIRN1207 3

External Ids for MIR1207 Gene

Previous HGNC Symbols for MIR1207 Gene

  • MIRN1207

Previous GeneCards Identifiers for MIR1207 Gene

  • GC00U923151
  • GC08P129131
  • GC08P129061

Summaries for MIR1207 Gene

Entrez Gene Summary for MIR1207 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1207 Gene

MIR1207 (MicroRNA 1207) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1207 Gene

Genomics for MIR1207 Gene

Regulatory Elements for MIR1207 Gene

Enhancers for MIR1207 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F128073 0.4 ENCODE 12.2 +24.6 24642 1.0 FOSL1 MIR1207 RNU4-25P MIR1208 ENSG00000280151
GH08F128076 0.9 Ensembl ENCODE 12.1 +28.2 28176 2.5 PKNOX1 BMI1 FOS CREM CBFB USF2 JUNB TBX21 RAD51 IKZF1 MIR1207 RNU4-25P MIR1208 ENSG00000280151
GH08F128074 0.2 ENCODE 12.1 +25.7 25738 0.2 FOSL1 NR2F1 EHMT2 KDM1A MIR1207 RNU4-25P MIR1208 ENSG00000280151
GH08F128017 1 Ensembl ENCODE 11.2 -30.3 -30306 2.2 STAT1 ZNF175 SIN3A CHD7 REST GATA3 JUND SMARCA4 POLR2A IKZF1 MIR1207 TMEM75 MIR1204 PVT1 RNU1-106P RNU4-25P
GH08F128087 0.5 ENCODE 11.1 +39.6 39637 1.8 ZNF687 RFX1 ZHX2 SIN3A DPF2 RAD21 ZNF592 ZNF217 MBD2 GATA3 MIR1207 RNU1-106P RNU4-25P MIR1208 ENSG00000280151
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1207 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1207 Gene

Chromosome:
8
Start:
128,049,152 bp from pter
End:
128,049,238 bp from pter
Size:
87 bases
Orientation:
Plus strand

Genomic View for MIR1207 Gene

Genes around MIR1207 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1207 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1207 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1207 Gene

Proteins for MIR1207 Gene

Post-translational modifications for MIR1207 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1207 Gene

Domains & Families for MIR1207 Gene

Gene Families for MIR1207 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1207: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1207 Gene

Function for MIR1207 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1207 Gene

Localization for MIR1207 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1207 Gene

Pathways & Interactions for MIR1207 Gene

SuperPathways for MIR1207 Gene

No Data Available

Interacting Proteins for MIR1207 Gene

Gene Ontology (GO) - Biological Process for MIR1207 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1207 Gene

Transcripts for MIR1207 Gene

mRNA/cDNA for MIR1207 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1207 Gene

No ASD Table

Relevant External Links for MIR1207 Gene

GeneLoc Exon Structure for
MIR1207
ECgene alternative splicing isoforms for
MIR1207

Expression for MIR1207 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1207 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1207 Gene:

MIR1207
genes like me logo Genes that share expression patterns with MIR1207: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1207 Gene

Orthologs for MIR1207 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1207 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1207 35
  • 99 (a)
OneToOne
Species where no ortholog for MIR1207 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1207 Gene

ENSEMBL:
Gene Tree for MIR1207 (if available)
TreeFam:
Gene Tree for MIR1207 (if available)

Paralogs for MIR1207 Gene

No data available for Paralogs for MIR1207 Gene

Variants for MIR1207 Gene

Sequence variations from dbSNP and Humsavar for MIR1207 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10106014 -- 128,047,566(+) GCACA(C/G)GAAAA intron-variant, upstream-variant-2KB
rs112490570 -- 128,048,396(+) CTCCC(A/G)TCCTT intron-variant, upstream-variant-2KB
rs112837154 -- 128,048,722(+) GAAGC(A/T)AAAAA intron-variant, upstream-variant-2KB
rs112969224 -- 128,048,808(+) GAAAG(A/C)GCTTA intron-variant, upstream-variant-2KB
rs114559408 -- 128,048,237(+) GCACA(A/C/T)AATAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1207 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855

Relevant External Links for MIR1207 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1207

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1207 Gene

Disorders for MIR1207 Gene

Relevant External Links for MIR1207

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1207

No disorders were found for MIR1207 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1207 Gene

Publications for MIR1207 Gene

  1. miRNA-1207-5p is associated with cancer progression by targeting stomatin-like protein 2 in esophageal carcinoma. (PMID: 25695396) Yang X. … Zhao G. (Int. J. Oncol. 2015) 3 64
  2. MiR-1207 overexpression promotes cancer stem cell-like traits in ovarian cancer by activating the Wnt/I^-catenin signaling pathway. (PMID: 26337084) Wu G. … He S. (Oncotarget 2015) 3 64
  3. miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase. (PMID: 24481448) Chen L. … Yang S.M. (Cell Death Dis 2014) 3 64
  4. Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy. (PMID: 24204837) Alvarez M.L. … Kiefer J. (PLoS ONE 2013) 3 64
  5. A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy. (PMID: 22319602) Papagregoriou G. … Deltas C. (PLoS ONE 2012) 3 64

Products for MIR1207 Gene

Sources for MIR1207 Gene

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