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Aliases for MIR1185-1 Gene

Subcategory (RNA class) for MIR1185-1 Gene


Quality Score for this RNA gene is


Aliases for MIR1185-1 Gene

  • MicroRNA 1185-1 2 3 5
  • Hsa-Mir-1185-1 3
  • Mir-1185-1 3
  • MIRN1185-1 3

External Ids for MIR1185-1 Gene

Previous HGNC Symbols for MIR1185-1 Gene

  • MIRN1185-1

Previous GeneCards Identifiers for MIR1185-1 Gene

  • GC00U923058
  • GC14P100937
  • GC14P101513
  • GC14P101542
  • GC14P101575
  • GC14P101616
  • GC14P101644
  • GC14P101677
  • GC14P101714
  • GC14P101756
  • GC14P101815
  • GC14P101955
  • GC14P102151
  • GC14P101253
  • GC14P101862
  • GC14P102113
  • GC14P102349
  • GC14P102520
  • GC14P102699

Summaries for MIR1185-1 Gene

Entrez Gene Summary for MIR1185-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1185-1 Gene

MIR1185-1 (MicroRNA 1185-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1185-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1185-1 Gene

Genomics for MIR1185-1 Gene

Regulatory Elements for MIR1185-1 Gene

Enhancers for MIR1185-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H101287 1 ENCODE 9.4 +245.9 245944 2.5 FOXA2 ATF1 MLX ZFP64 ARID4B YY1 SP5 ZHX2 NFYC REST MEG3 MIR1185-2 MIR381 MIR487B MIR539 MIR544A MIR889 MIR655 MIR1185-1 MIR300
GH14H101004 0.8 Ensembl ENCODE 10.9 -37.9 -37893 1.9 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR154 MIR485 MIR323B MIR496 MIR377 MIR376C MIR300 MIR654
GH14H101096 0.8 FANTOM5 ENCODE 10.7 +55.4 55371 3.2 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR541 MIR656 MIR412 MIR410 MIR377
GH14H101330 0.9 ENCODE 8.9 +287.9 287878 0.3 ELF3 FOXA2 MLX ARID4B RAD21 THRB ZSCAN9 RARA CREM MIXL1 MIR1185-1 MIR1185-2 MIR300 MIR381 MIR487B MIR544A MIR655 MIR889 MIR539 MIR376C
GH14H101333 0.9 ENCODE 8.9 +292.1 292080 2.2 ELF3 FOXA2 ARID4B ZSCAN9 RAD21 RARA YY1 CREM MIXL1 THAP11 MIR381 MIR487B MIR655 MIR889 MIR544A MIR539 MIR376C MIR1185-1 MIR1185-2 MIR300
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1185-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1185-1 Gene

Genomic Locations for MIR1185-1 Gene
86 bases
Plus strand

Genomic View for MIR1185-1 Gene

Genes around MIR1185-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1185-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1185-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1185-1 Gene

Proteins for MIR1185-1 Gene

Post-translational modifications for MIR1185-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1185-1 Gene

Domains & Families for MIR1185-1 Gene

Gene Families for MIR1185-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1185-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1185-1 Gene

Function for MIR1185-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1185-1 Gene

Localization for MIR1185-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1185-1 Gene

Pathways & Interactions for MIR1185-1 Gene

SuperPathways for MIR1185-1 Gene

No Data Available

Interacting Proteins for MIR1185-1 Gene

Gene Ontology (GO) - Biological Process for MIR1185-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1185-1 Gene

Drugs & Compounds for MIR1185-1 Gene

No Compound Related Data Available

Transcripts for MIR1185-1 Gene

mRNA/cDNA for MIR1185-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1185-1 Gene

No ASD Table

Relevant External Links for MIR1185-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1185-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1185-1 Gene

genes like me logo Genes that share expression patterns with MIR1185-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1185-1 Gene

Orthologs for MIR1185-1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1185-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1185-1 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-1185 34
  • 98 (a)
(Canis familiaris)
Mammalia -- 34
  • 80 (a)
Species where no ortholog for MIR1185-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1185-1 Gene

Gene Tree for MIR1185-1 (if available)
Gene Tree for MIR1185-1 (if available)

Paralogs for MIR1185-1 Gene

No data available for Paralogs for MIR1185-1 Gene

Variants for MIR1185-1 Gene

Sequence variations from dbSNP and Humsavar for MIR1185-1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000743646 -- 101,042,869(+) AGCCA(C/G)ATGAG upstream-variant-2KB
rs1001989412 -- 101,043,140(+) GGCTT(G/T)GCTTC downstream-variant-500B, upstream-variant-2KB
rs1002530539 -- 101,041,060(+) CATTG(A/G)CCTTG downstream-variant-500B, upstream-variant-2KB
rs1003604401 -- 101,041,217(+) AATAG(A/G)TGTGT downstream-variant-500B, upstream-variant-2KB
rs1004674820 -- 101,041,701(+) GGCCG(G/T)GCACG downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1185-1 Gene

Variant ID Type Subtype PubMed ID
nsv565860 CNV gain 21841781
nsv565859 CNV gain 21841781
nsv1040993 CNV gain 25217958
esv3635521 CNV gain 21293372

Relevant External Links for MIR1185-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1185-1 Gene

Disorders for MIR1185-1 Gene

Relevant External Links for MIR1185-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1185-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1185-1 Gene

Publications for MIR1185-1 Gene

  1. MicroRNA-1185 Induces Endothelial Cell Apoptosis by Targeting UVRAG and KRIT1. (PMID: 28441650) Deng H … Li Y (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 60
  2. MicroRNA-1185 Promotes Arterial Stiffness though Modulating VCAM-1 and E-Selectin Expression. (PMID: 28441665) Deng H … Li Y (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 60
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  4. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S … van de Rijn M (Oncogene 2008) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1185-1 Gene

Sources for MIR1185-1 Gene

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