Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1182 Gene

Subcategory (RNA class) for MIR1182 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1182 Gene

  • MicroRNA 1182 2 3
  • FAM89A 4 5
  • Family With Sequence Similarity 89 Member A 5
  • Hsa-Mir-1182 3
  • C1orf153 4
  • MIRN1182 3

External Ids for MIR1182 Gene

Previous HGNC Symbols for MIR1182 Gene

  • MIRN1182

Previous GeneCards Identifiers for MIR1182 Gene

  • GC00U922908
  • GC01M229223
  • GC01M231155

Summaries for MIR1182 Gene

Entrez Gene Summary for MIR1182 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1182 Gene

MIR1182 (MicroRNA 1182) is an RNA Gene, and is affiliated with the miRNA class. An important paralog of this gene is FAM89B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1182 Gene

Genomics for MIR1182 Gene

Regulatory Elements for MIR1182 Gene

Enhancers for MIR1182 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR1182 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1182 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR1182 Gene

Chromosome:
1
Start:
231,018,958 bp from pter
End:
231,040,246 bp from pter
Size:
21,289 bases
Orientation:
Minus strand

Genomic View for MIR1182 Gene

Genes around MIR1182 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1182 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1182 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1182 Gene

ORGUL Member Location for MIR1182 Gene

ORGUL Member Location for MIR1182 gene

Proteins for MIR1182 Gene

  • Protein details for MIR1182 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GI7-FA89A_HUMAN
    Recommended name:
    Protein FAM89A
    Protein Accession:
    Q96GI7

    Protein attributes for MIR1182 Gene

    Size:
    184 amino acids
    Molecular mass:
    19569 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MIR1182 Gene

Post-translational modifications for MIR1182 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MIR1182 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for MIR1182 Gene

Domains & Families for MIR1182 Gene

Gene Families for MIR1182 Gene

Protein Domains for MIR1182 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96GI7

UniProtKB/Swiss-Prot:

FA89A_HUMAN :
  • Belongs to the FAM89 family.
Family:
  • Belongs to the FAM89 family.
genes like me logo Genes that share domains with MIR1182: view

No data available for Suggested Antigen Peptide Sequences for MIR1182 Gene

Function for MIR1182 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1182 Gene

Localization for MIR1182 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1182 Gene

Pathways & Interactions for MIR1182 Gene

SuperPathways for MIR1182 Gene

No Data Available

Interacting Proteins for MIR1182 Gene

Gene Ontology (GO) - Biological Process for MIR1182 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1182 Gene

Drugs & Compounds for MIR1182 Gene

No Compound Related Data Available

Transcripts for MIR1182 Gene

mRNA/cDNA for MIR1182 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1182 Gene

No ASD Table

Relevant External Links for MIR1182 Gene

GeneLoc Exon Structure for
MIR1182
ECgene alternative splicing isoforms for
MIR1182

Expression for MIR1182 Gene

mRNA expression in normal human tissues for MIR1182 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1182 Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x5.5) and Adipose - Subcutaneous (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of MIR1182 Gene:

MIR1182
genes like me logo Genes that share expression patterns with MIR1182: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1182 Gene

Orthologs for MIR1182 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR1182 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM89A 35
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM89A 35
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM89A 35
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam89a 35
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1182 35
  • 99 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM89A 35
  • 76 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii fam89a 35
  • 42 (a)
OneToOne
Species where no ortholog for MIR1182 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR1182 Gene

ENSEMBL:
Gene Tree for MIR1182 (if available)
TreeFam:
Gene Tree for MIR1182 (if available)

Paralogs for MIR1182 Gene

Paralogs for MIR1182 Gene

genes like me logo Genes that share paralogs with MIR1182: view

Variants for MIR1182 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1182 Gene

Variant ID Type Subtype PubMed ID
esv3589093 CNV gain 21293372
nsv1000488 CNV gain 25217958
nsv1011066 CNV gain 25217958

Relevant External Links for MIR1182 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1182

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR1182 Gene

Disorders for MIR1182 Gene

Relevant External Links for MIR1182

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1182

No disorders were found for MIR1182 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1182 Gene

Publications for MIR1182 Gene

  1. miR-1182 inhibits growth and mediates the chemosensitivity of bladder cancer by targeting hTERT. (PMID: 26772886) Zhou J. … Song J. (Biochem. Biophys. Res. Commun. 2016) 3 65
  2. miR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame of hTERT. (PMID: 25662441) Zhang D. … Yang S.M. (Cancer Lett. 2015) 3 65
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 65
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  5. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S. … van de Rijn M. (Oncogene 2008) 3 65

Products for MIR1182 Gene

Sources for MIR1182 Gene

Content
Loading form....