Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1182 Gene

Subcategory (RNA class) for MIR1182 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1182 Gene

  • MicroRNA 1182 2 3 5
  • Hsa-Mir-1182 3
  • MIRN1182 3

External Ids for MIR1182 Gene

Previous HGNC Symbols for MIR1182 Gene

  • MIRN1182

Previous GeneCards Identifiers for MIR1182 Gene

  • GC00U922908
  • GC01M229223
  • GC01M231155

Summaries for MIR1182 Gene

Entrez Gene Summary for MIR1182 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1182 Gene

MIR1182 (MicroRNA 1182) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1182 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1182 Gene

Genomics for MIR1182 Gene

GeneHancer (GH) Regulatory Elements for MIR1182 Gene

Promoters and enhancers for MIR1182 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I231019 Enhancer 0.6 Ensembl ENCODE 550.8 -0.8 -815 1.9 ZBTB40 SUPT5H ETS1 LOC644006 MIR1182 FAM89A LOC101927604 TTC13
GH01I231210 Enhancer 1.4 FANTOM5 Ensembl ENCODE 10.8 -192.0 -192012 2 ARID4B SIN3A ZNF2 IRF4 ZNF48 GLIS2 ZNF213 ELK1 ARID2 ZNF143 C1orf131 COG2 GNPAT FAM89A MIR1182 LOC644006 LOC101927604 C1orf198 SPRTN LOC149373
GH01I231053 Enhancer 1.1 Ensembl ENCODE 11.1 -33.8 -33806 1.1 HDGF FOXA2 PKNOX1 YY1 ZNF766 ATF7 RXRA REST MEF2D SMARCA4 MIR1182 LOC644006 GC01M231050 FAM89A
GH01I231049 Enhancer 1 ENCODE 12 -29.6 -29582 0.9 HDGF PKNOX1 CLOCK ATF1 ARNT ZNF766 E2F8 FOS ATF7 CAVIN1 MIR1182 LOC644006 FAM89A GC01M231050
GH01I231200 Enhancer 1 ENCODE 10.7 -180.6 -180593 0.8 PKNOX1 ATF1 ARNT FEZF1 TCF12 ZNF766 GATA2 ATF7 NCOA1 REST FAM89A LOC644006 MIR1182 LOC149373 TRIM67 GNPAT
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1182 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1182 Gene

Genomic Locations for MIR1182 Gene
chr1:231,019,828-231,019,924
(GRCh38/hg38)
Size:
97 bases
Orientation:
Minus strand
chr1:231,155,574-231,155,670
(GRCh37/hg19)

Genomic View for MIR1182 Gene

Genes around MIR1182 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1182 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1182 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1182 Gene

ORGUL Member Location for MIR1182 Gene

ORGUL Member Location for MIR1182 gene

Proteins for MIR1182 Gene

Post-translational modifications for MIR1182 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1182 Gene

Domains & Families for MIR1182 Gene

Gene Families for MIR1182 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1182: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1182 Gene

Function for MIR1182 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1182 Gene

Localization for MIR1182 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1182 Gene

Pathways & Interactions for MIR1182 Gene

SuperPathways for MIR1182 Gene

No Data Available

Interacting Proteins for MIR1182 Gene

Gene Ontology (GO) - Biological Process for MIR1182 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1182 Gene

Drugs & Compounds for MIR1182 Gene

No Compound Related Data Available

Transcripts for MIR1182 Gene

mRNA/cDNA for MIR1182 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1182 Gene

No ASD Table

Relevant External Links for MIR1182 Gene

GeneLoc Exon Structure for
MIR1182
ECgene alternative splicing isoforms for
MIR1182

Expression for MIR1182 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1182 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1182 Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x5.5) and Adipose - Subcutaneous (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of MIR1182 Gene:

MIR1182
genes like me logo Genes that share expression patterns with MIR1182: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1182 Gene

Orthologs for MIR1182 Gene

Evolution for MIR1182 Gene

ENSEMBL:
Gene Tree for MIR1182 (if available)
TreeFam:
Gene Tree for MIR1182 (if available)

No data available for Orthologs for MIR1182 Gene

Paralogs for MIR1182 Gene

No data available for Paralogs for MIR1182 Gene

Variants for MIR1182 Gene

Sequence variations from dbSNP and Humsavar for MIR1182 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000857816 -- 231,020,309(-) T/C upstream_transcript_variant
rs1001298454 -- 231,020,140(-) G/A upstream_transcript_variant
rs1002706336 -- 231,020,951(-) A/G upstream_transcript_variant
rs1004996659 -- 231,020,182(-) T/C upstream_transcript_variant
rs1005571201 -- 231,021,168(-) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1182 Gene

Variant ID Type Subtype PubMed ID
esv3589093 CNV gain 21293372
nsv1000488 CNV gain 25217958
nsv1011066 CNV gain 25217958

Additional Variant Information for MIR1182 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1182

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1182 Gene

Disorders for MIR1182 Gene

Additional Disease Information for MIR1182

No disorders were found for MIR1182 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1182 Gene

Publications for MIR1182 Gene

  1. miR-1182 inhibits growth and mediates the chemosensitivity of bladder cancer by targeting hTERT. (PMID: 26772886) Zhou J … Song J (Biochemical and biophysical research communications 2016) 3 58
  2. miR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame of hTERT. (PMID: 25662441) Zhang D … Yang SM (Cancer letters 2015) 3 58
  3. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S … van de Rijn M (Oncogene 2008) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1182 Gene

Sources for MIR1182 Gene

Content
Loading form....