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Aliases for MIR1181 Gene

Subcategory (RNA class) for MIR1181 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1181 Gene

  • MicroRNA 1181 2 3 5
  • Hsa-Mir-1181 3
  • MIRN1181 3

External Ids for MIR1181 Gene

Previous HGNC Symbols for MIR1181 Gene

  • MIRN1181

Previous GeneCards Identifiers for MIR1181 Gene

  • GC00U923040
  • GC19M010514

Summaries for MIR1181 Gene

Entrez Gene Summary for MIR1181 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1181 Gene

MIR1181 (MicroRNA 1181) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Aryl Hydrocarbon Receptor and Signaling by Ligand-Responsive EGFR Variants in Cancer.

Additional gene information for MIR1181 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1181 Gene

Genomics for MIR1181 Gene

GeneHancer (GH) Regulatory Elements for MIR1181 Gene

Promoters and enhancers for MIR1181 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I010400 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 550.8 -0.7 -679 6.5 HDGF ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B E2F8 ZNF207 MIR1181 CDC37 ICAM1 MRPL4 ICAM5 ICAM4 RAVER1 PDE4A TYK2 C19orf38
GH19I010407 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 -5.3 -5298 2.1 MAX EBF1 IRF4 ZFHX2 POLR2A ZNF366 EGR1 ATF7 ZSCAN29 ETV6 TYK2 FDX2 PDE4A C19orf38 ICAM3 S1PR5 ATG4D P2RY11 GC19P010412 MIR1181
GH19I010399 Enhancer 0.5 ENCODE 0.8 +4.4 4418 0.2 BCOR ZNF316 DPF2 NFE2 EMSY CDC37 ICAM1 MRPL4 ICAM5 ICAM4 RAVER1 MIR1181 GC19P010382
GH19I010388 Enhancer 0.8 ENCODE 0.4 +14.5 14478 0.2 PKNOX1 ARID4B SIN3A RAD21 ARID2 ZNF207 ZNF143 BCLAF1 IKZF2 DEK ZGLP1 ICAM5 ICAM1 MRPL4 ICAM4 EIF3G GC19P010382 MIR1181
GH19I010390 Enhancer 0.8 ENCODE 0.4 +12.7 12668 0.2 CTCF RB1 TEAD4 SIN3A ZNF384 EBF1 RAD21 ZKSCAN1 TEAD3 ZFHX2 ZGLP1 ICAM5 ICAM1 MRPL4 ICAM4 EIF3G GC19P010382 MIR1181
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1181 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1181 Gene

Genomic Locations for MIR1181 Gene
chr19:10,403,458-10,403,538
(GRCh38/hg38)
Size:
81 bases
Orientation:
Minus strand
chr19:10,514,134-10,514,214
(GRCh37/hg19)

Genomic View for MIR1181 Gene

Genes around MIR1181 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1181 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1181 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1181 Gene

Proteins for MIR1181 Gene

Post-translational modifications for MIR1181 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1181 Gene

Domains & Families for MIR1181 Gene

Gene Families for MIR1181 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1181: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1181 Gene

Function for MIR1181 Gene

Phenotypes From GWAS Catalog for MIR1181 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1181 Gene

Localization for MIR1181 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1181 Gene

Drugs & Compounds for MIR1181 Gene

No Compound Related Data Available

Transcripts for MIR1181 Gene

mRNA/cDNA for MIR1181 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1181 Gene

No ASD Table

Relevant External Links for MIR1181 Gene

GeneLoc Exon Structure for
MIR1181
ECgene alternative splicing isoforms for
MIR1181

Expression for MIR1181 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1181 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1181 Gene:

MIR1181
genes like me logo Genes that share expression patterns with MIR1181: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1181 Gene

Orthologs for MIR1181 Gene

Evolution for MIR1181 Gene

ENSEMBL:
Gene Tree for MIR1181 (if available)
TreeFam:
Gene Tree for MIR1181 (if available)

No data available for Orthologs for MIR1181 Gene

Paralogs for MIR1181 Gene

No data available for Paralogs for MIR1181 Gene

Variants for MIR1181 Gene

Sequence variations from dbSNP and Humsavar for MIR1181 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1001621897 -- 10,403,268(-) G/A/T downstream_transcript_variant
rs1002902363 -- 10,404,705(-) G/C upstream_transcript_variant
rs1003252394 -- 10,403,828(-) G/T upstream_transcript_variant
rs1003636734 -- 10,404,838(-) CCCC/CCCCC upstream_transcript_variant
rs1005368512 -- 10,403,191(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1181 Gene

Variant ID Type Subtype PubMed ID
nsv518008 CNV gain 19592680

Additional Variant Information for MIR1181 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1181

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1181 Gene

Disorders for MIR1181 Gene

Additional Disease Information for MIR1181

No disorders were found for MIR1181 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1181 Gene

Publications for MIR1181 Gene

  1. miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer. (PMID: 28321160) Wang J … Jiang JX (World journal of gastroenterology 2017) 3 58
  2. Activation of ARK5/miR-1181/HOXA10 axis promotes epithelial-mesenchymal transition in ovarian cancer. (PMID: 26151663) Zhang HY … Wang SR (Oncology reports 2015) 3 58
  3. MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer. (PMID: 25444909) Jiang J … Sun C (Cancer letters 2015) 3 58
  4. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B … Wang LS (Journal of proteome research 2012) 3 58
  5. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S … van de Rijn M (Oncogene 2008) 3 58

Products for MIR1181 Gene

Sources for MIR1181 Gene

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