Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1181 Gene

Subcategory (RNA class) for MIR1181 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1181 Gene

  • MicroRNA 1181 2 3 5
  • Hsa-Mir-1181 3
  • MIRN1181 3

External Ids for MIR1181 Gene

Previous HGNC Symbols for MIR1181 Gene

  • MIRN1181

Previous GeneCards Identifiers for MIR1181 Gene

  • GC00U923040
  • GC19M010514

Summaries for MIR1181 Gene

Entrez Gene Summary for MIR1181 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1181 Gene

MIR1181 (MicroRNA 1181) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Signaling by EGFR in Cancer and HIV Life Cycle.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1181 Gene

Genomics for MIR1181 Gene

Regulatory Elements for MIR1181 Gene

Enhancers for MIR1181 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G010400 1.5 FANTOM5 ENCODE 0.7 -0.7 -680 6.5 HDGF FOXA2 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 YY1 ICAM1 ZNF846 LOC100419831 MRPL4 ICAM5 ICAM4 RAVER1 QTRT1 PDE4A ILF3-AS1
GH19G010407 1.5 FANTOM5 Ensembl ENCODE 0.4 -5.3 -5298 2.1 TBL1XR1 ZNF48 ZNF121 GLIS2 EGR1 ZNF366 ETV6 RELB IKZF2 CREM TYK2 FDX2 PDE4A C19orf38 ICAM3 S1PR5 ATG4D P2RY11 GC19P010412 MIR1181
GH19G010399 0.6 ENCODE 0.7 +4.4 4419 0.2 BCOR ZNF316 FOXA2 JUND DPF2 NFE2 EMSY FOXA1 CDC37 ICAM1 MRPL4 ICAM5 ICAM4 RAVER1 MIR1181 GC19P010382
GH19G010388 0.9 ENCODE 0.4 +14.5 14479 0.2 PKNOX1 SIN3A ARID4B RAD21 ZNF143 ZNF207 RELB IKZF2 DEK PAF1 ZGLP1 ICAM5 ICAM1 MRPL4 ICAM4 EIF3G GC19P010382 MIR1181
GH19G010390 0.8 ENCODE 0.4 +12.7 12669 0.2 RAD21 EGR1 ZNF143 RELB IKZF2 DEK EGR2 ZNF654 ZNF362 REST ZGLP1 ICAM5 ICAM1 MRPL4 ICAM4 EIF3G GC19P010382 MIR1181
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1181 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1181 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000107005 -162 2601 HDGF CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143

Genomic Location for MIR1181 Gene

Chromosome:
19
Start:
10,403,458 bp from pter
End:
10,403,538 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR1181 Gene

Genes around MIR1181 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1181 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1181 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1181 Gene

Proteins for MIR1181 Gene

Post-translational modifications for MIR1181 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1181 Gene

Domains & Families for MIR1181 Gene

Gene Families for MIR1181 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1181: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1181 Gene

Function for MIR1181 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1181 Gene

Localization for MIR1181 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1181 Gene

Drugs & Compounds for MIR1181 Gene

No Compound Related Data Available

Transcripts for MIR1181 Gene

mRNA/cDNA for MIR1181 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1181 Gene

No ASD Table

Relevant External Links for MIR1181 Gene

GeneLoc Exon Structure for
MIR1181
ECgene alternative splicing isoforms for
MIR1181

Expression for MIR1181 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1181 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1181 Gene:

MIR1181
genes like me logo Genes that share expression patterns with MIR1181: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1181 Gene

Orthologs for MIR1181 Gene

Evolution for MIR1181 Gene

ENSEMBL:
Gene Tree for MIR1181 (if available)
TreeFam:
Gene Tree for MIR1181 (if available)

No data available for Orthologs for MIR1181 Gene

Paralogs for MIR1181 Gene

No data available for Paralogs for MIR1181 Gene

Variants for MIR1181 Gene

Sequence variations from dbSNP and Humsavar for MIR1181 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1001621897 -- 10,403,268(+) GACTG(A/G/T)GGGGG intron-variant, downstream-variant-500B
rs1002902363 -- 10,404,705(+) AGAAG(C/G)GGGAG upstream-variant-2KB
rs1003252394 -- 10,403,828(+) GGGAC(G/T)GTTGA upstream-variant-2KB
rs1003636734 -- 10,404,837(+) TCCTA(-/C)CCCCT upstream-variant-2KB
rs1005368512 -- 10,403,191(+) GCGGA(A/G)ATCCA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1181 Gene

Variant ID Type Subtype PubMed ID
nsv518008 CNV gain 19592680

Relevant External Links for MIR1181 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1181

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1181 Gene

Disorders for MIR1181 Gene

Relevant External Links for MIR1181

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1181

No disorders were found for MIR1181 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1181 Gene

Publications for MIR1181 Gene

  1. MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer. (PMID: 25444909) Jiang J. … Sun C. (Cancer Lett. 2015) 3 64
  2. Activation of ARK5/miR-1181/HOXA10 axis promotes epithelial-mesenchymal transition in ovarian cancer. (PMID: 26151663) Zhang H.Y. … Wang S.R. (Oncol. Rep. 2015) 3 64
  3. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 3 64
  4. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S. … van de Rijn M. (Oncogene 2008) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1181 Gene

Sources for MIR1181 Gene

Content
Loading form....