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Aliases for MIR1180 Gene

Subcategory (RNA class) for MIR1180 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1180 Gene

  • MicroRNA 1180 2 3 5
  • Hsa-Mir-1180 3
  • Mir-1180 3
  • MIRN1180 3

External Ids for MIR1180 Gene

Previous HGNC Symbols for MIR1180 Gene

  • MIRN1180

Previous GeneCards Identifiers for MIR1180 Gene

  • GC00U923106
  • GC17M019190

Summaries for MIR1180 Gene

Entrez Gene Summary for MIR1180 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1180 Gene

MIR1180 (MicroRNA 1180) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1180 Gene

Genomics for MIR1180 Gene

Regulatory Elements for MIR1180 Gene

Enhancers for MIR1180 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F019368 1.2 FANTOM5 Ensembl ENCODE 12.8 -26.5 -26527 5.8 HDGF HDAC1 KLF1 ATF1 PKNOX1 SAP130 ZMYM3 ARID4B EBF1 RARA ENSG00000262319 MIR1180 ENSG00000262292 ENSG00000235979 ENSG00000230197 MAPK7 FAM83G LOC105371573
GH17F019432 0.2 ENCODE 12 -89.2 -89229 1.7 TBP ELF3 MLX ARID4B DMAP1 RAD21 ZNF48 YY1 RARA MIXL1 MFAP4 B9D1 MAPK7 MIR1180 SLC47A1 EPN2 ENSG00000235979 ENSG00000283675 RPS2P46
GH17F019236 1.1 FANTOM5 ENCODE 11.1 +106.7 106716 2.2 SIN3A KAT2B GLIS2 EGR1 SCRT2 EGR2 SP3 ZNF341 GLIS1 IKZF1 LOC102724624 ENSG00000262319 MIR1180 ENSG00000230197 RNF112 EPN2 LOC388436 EPN2-IT1
GH17F019239 0.5 ENCODE 11.1 +105.4 105440 0.3 KDM1A EGR2 ENSG00000262319 MIR1180 SLC5A10 LOC388436 EPN2-IT1
GH17F019345 1.3 Ensembl ENCODE 0.8 -2.4 -2441 3.5 PKNOX1 ZFP64 SIN3A ZNF2 YY1 FOS TSHZ1 SMARCA4 PBX2 GLIS1 ENSG00000262319 ENSG00000230197 RNF112 MIR1180 LOC105371573
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1180 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1180 Gene

Chromosome:
17
Start:
19,344,506 bp from pter
End:
19,344,574 bp from pter
Size:
69 bases
Orientation:
Minus strand

Genomic View for MIR1180 Gene

Genes around MIR1180 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1180 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1180 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1180 Gene

ORGUL Member Location for MIR1180 Gene

ORGUL Member Location for MIR1180 gene

Proteins for MIR1180 Gene

Post-translational modifications for MIR1180 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1180 Gene

Domains & Families for MIR1180 Gene

Gene Families for MIR1180 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1180: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1180 Gene

Function for MIR1180 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1180 Gene

Localization for MIR1180 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1180 Gene

Pathways & Interactions for MIR1180 Gene

SuperPathways for MIR1180 Gene

No Data Available

Interacting Proteins for MIR1180 Gene

Gene Ontology (GO) - Biological Process for MIR1180 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1180 Gene

Transcripts for MIR1180 Gene

mRNA/cDNA for MIR1180 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1180 Gene

No ASD Table

Relevant External Links for MIR1180 Gene

GeneLoc Exon Structure for
MIR1180
ECgene alternative splicing isoforms for
MIR1180

Expression for MIR1180 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1180 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1180 Gene:

MIR1180
genes like me logo Genes that share expression patterns with MIR1180: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1180 Gene

Orthologs for MIR1180 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1180 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 35
  • 73 (a)
OneToOne
Species where no ortholog for MIR1180 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1180 Gene

ENSEMBL:
Gene Tree for MIR1180 (if available)
TreeFam:
Gene Tree for MIR1180 (if available)

Paralogs for MIR1180 Gene

No data available for Paralogs for MIR1180 Gene

Variants for MIR1180 Gene

Sequence variations from dbSNP and Humsavar for MIR1180 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs11204301 -- 19,344,191(+) GTGCT(A/G)CCTGA intron-variant, downstream-variant-500B
rs112899104 -- 19,345,403(+) AATGA(C/T)GGCCC intron-variant, upstream-variant-2KB
rs117055930 -- 19,344,790(+) GCTCT(C/G/T)AGCTG intron-variant, upstream-variant-2KB
rs12602433 -- 19,344,073(+) CAGGC(C/T)TCATG intron-variant, downstream-variant-500B
rs138538107 -- 19,346,544(+) TCCTC(A/G)AGTCA intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1180 Gene

Variant ID Type Subtype PubMed ID
esv3582561 CNV loss 25503493
nsv1061317 CNV gain 25217958
nsv833393 CNV gain+loss 17160897

Relevant External Links for MIR1180 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1180

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1180 Gene

Disorders for MIR1180 Gene

Relevant External Links for MIR1180

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1180

No disorders were found for MIR1180 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1180 Gene

Publications for MIR1180 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing. (PMID: 19508715) Nygaard S. … Litman T. (BMC Med Genomics 2009) 3 64
  4. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S. … van de Rijn M. (Oncogene 2008) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1180 Gene

Sources for MIR1180 Gene

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