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Aliases for MIR1180 Gene

Subcategory (RNA class) for MIR1180 Gene


Quality Score for this RNA gene is


Aliases for MIR1180 Gene

  • MicroRNA 1180 2 3 5
  • Hsa-Mir-1180 3
  • Mir-1180 3
  • MIRN1180 3

External Ids for MIR1180 Gene

Previous HGNC Symbols for MIR1180 Gene

  • MIRN1180

Previous GeneCards Identifiers for MIR1180 Gene

  • GC00U923106
  • GC17M019190

Summaries for MIR1180 Gene

Entrez Gene Summary for MIR1180 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1180 Gene

MIR1180 (MicroRNA 1180) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1180 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1180 Gene

Genomics for MIR1180 Gene

Regulatory Elements for MIR1180 Gene

Enhancers for MIR1180 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H019368 1.7 FANTOM5 Ensembl ENCODE dbSUPER 12.8 -25.6 -25568 2.8 HDGF KLF1 SAP130 ARID4B EBF1 RARA ZKSCAN1 EED RUNX3 IKZF2 MIR1180 ENSG00000262292 ZNF286B MAPK7 FAM83G LOC105371573
GH17H019236 1.5 FANTOM5 ENCODE dbSUPER 11.1 +106.7 106716 2.2 RB1 SIN3A GLIS2 EGR1 SCRT2 ZNF143 EGR2 SMARCA5 SP3 KLF16 LOC102724624 ENSG00000262319 MIR1180 ENSG00000230197 RNF112 EPN2 LOC388436 EPN2-IT1
GH17H019239 0.7 ENCODE dbSUPER 11.1 +105.4 105440 0.3 EGR1 KDM1A EGR2 ENSG00000262319 MIR1180 SLC5A10 LOC388436 EPN2-IT1
GH17H019432 0.4 ENCODE 12 -89.2 -89229 1.7 HLF ZIC2 MFAP4 MAPK7 B9D1 MIR1180 SLC47A1 EPN2 ENSG00000235979 ENSG00000189343 ENSG00000283675
GH17H019322 0.2 dbSUPER 12.6 +21.5 21518 0.8 MIR1180 ENSG00000262292 PIR38644 EPN2-AS1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1180 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1180 Gene

Genomic Locations for MIR1180 Gene
69 bases
Minus strand

Genomic View for MIR1180 Gene

Genes around MIR1180 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1180 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1180 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1180 Gene

ORGUL Member Location for MIR1180 Gene

ORGUL Member Location for MIR1180 gene

Proteins for MIR1180 Gene

Post-translational modifications for MIR1180 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1180 Gene

Domains & Families for MIR1180 Gene

Gene Families for MIR1180 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1180: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1180 Gene

Function for MIR1180 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1180 Gene

Localization for MIR1180 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1180 Gene

Pathways & Interactions for MIR1180 Gene

SuperPathways for MIR1180 Gene

No Data Available

Interacting Proteins for MIR1180 Gene

Gene Ontology (GO) - Biological Process for MIR1180 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1180 Gene

Drugs & Compounds for MIR1180 Gene

No Compound Related Data Available

Transcripts for MIR1180 Gene

mRNA/cDNA for MIR1180 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1180 Gene

No ASD Table

Relevant External Links for MIR1180 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1180 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1180 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1180 Gene:

genes like me logo Genes that share expression patterns with MIR1180: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1180 Gene

Orthologs for MIR1180 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1180 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 34
  • 73 (a)
Species where no ortholog for MIR1180 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1180 Gene

Gene Tree for MIR1180 (if available)
Gene Tree for MIR1180 (if available)

Paralogs for MIR1180 Gene

No data available for Paralogs for MIR1180 Gene

Variants for MIR1180 Gene

Sequence variations from dbSNP and Humsavar for MIR1180 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000431344 -- 19,345,540(+) AAAGG(C/T)CAGGA intron-variant, upstream-variant-2KB
rs1000614911 -- 19,345,880(+) CCTCC(A/G)TATCT intron-variant, upstream-variant-2KB
rs1001922970 -- 19,345,041(+) CATCC(C/T)GGAGC intron-variant, upstream-variant-2KB
rs1003485298 -- 19,345,129(+) GGAGA(C/G)AAGAC intron-variant, upstream-variant-2KB
rs1005219858 -- 19,344,322(+) GGCCA(C/G)AACGG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1180 Gene

Variant ID Type Subtype PubMed ID
nsv833393 CNV gain+loss 17160897
nsv1061317 CNV gain 25217958
esv3582561 CNV loss 25503493

Relevant External Links for MIR1180 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1180 Gene

Disorders for MIR1180 Gene

Relevant External Links for MIR1180

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1180 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1180 Gene

Publications for MIR1180 Gene

  1. The suppressive effects of miR-1180-5p on the proliferation and tumorigenicity of bladder cancer cells. (PMID: 27112784) Ge Q … Ye Z (Histology and histopathology 2017) 3 60
  2. MiR-1180 promotes apoptotic resistance to human hepatocellular carcinoma via activation of NF-κB signaling pathway. (PMID: 26928365) Tan G … Li H (Scientific reports 2016) 3 60
  3. MiR-1180 promoted the proliferation of hepatocellular carcinoma cells by repressing TNIP2 expression. (PMID: 27044843) Zhou X … Lu J (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 60
  4. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 60
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60

Products for MIR1180 Gene

Sources for MIR1180 Gene

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