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Aliases for MIR1178 Gene

Subcategory (RNA class) for MIR1178 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1178 Gene

  • MicroRNA 1178 2 3 5
  • Hsa-Mir-1178 3
  • MIRN1178 3

External Ids for MIR1178 Gene

Previous HGNC Symbols for MIR1178 Gene

  • MIRN1178

Previous GeneCards Identifiers for MIR1178 Gene

  • GC00U922977
  • GC12M118636
  • GC12M120151

Summaries for MIR1178 Gene

Entrez Gene Summary for MIR1178 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1178 Gene

MIR1178 (MicroRNA 1178) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are G13 Signaling Pathway and Semaphorin interactions.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1178 Gene

Genomics for MIR1178 Gene

Regulatory Elements for MIR1178 Gene

Enhancers for MIR1178 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G119678 1.6 Ensembl ENCODE dbSUPER 12.3 +30.3 30294 9.7 HDGF FOXA2 PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 PRKAB1 MIR1178 CIT LOC105370027 TMEM233 ENSG00000255692
GH12G119715 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -2.7 -2711 2.0 FOXA2 MLX ARID4B SIN3A YY1 FOS PPARG KAT8 ZNF579 RCOR2 CIT TMEM233 PRKAB1 MIR1178 GC12P119728
GH12G119709 0.9 ENCODE dbSUPER 0.7 +2.9 2870 2.0 SIX4 ZNF263 PAF1 ZNF687 MNT ZNF121 POLR2A CREB1 KLF9 PRDM10 MIR1178 ENSG00000255692
GH12G119703 1.1 FANTOM5 ENCODE dbSUPER 0.4 +9.3 9304 2.3 ZFHX2 JUND POLR2A FOS SUPT5H ENSG00000255692 MIR1178
GH12G119718 0.4 dbSUPER 0.7 -4.9 -4946 0.9 PAF1 POLR2A CIT PRKAB1 TMEM233 MIR1178 GC12P119728
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1178 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1178 Gene

Chromosome:
12
Start:
119,713,634 bp from pter
End:
119,713,724 bp from pter
Size:
91 bases
Orientation:
Minus strand

Genomic View for MIR1178 Gene

Genes around MIR1178 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1178 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1178 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1178 Gene

Proteins for MIR1178 Gene

Post-translational modifications for MIR1178 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1178 Gene

Domains & Families for MIR1178 Gene

Gene Families for MIR1178 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1178: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1178 Gene

Function for MIR1178 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1178 Gene

Localization for MIR1178 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1178 Gene

Pathways & Interactions for MIR1178 Gene

genes like me logo Genes that share pathways with MIR1178: view

Pathways by source for MIR1178 Gene

1 BioSystems pathway for MIR1178 Gene

Interacting Proteins for MIR1178 Gene

Gene Ontology (GO) - Biological Process for MIR1178 Gene

None

No data available for SIGNOR curated interactions for MIR1178 Gene

Drugs & Compounds for MIR1178 Gene

No Compound Related Data Available

Transcripts for MIR1178 Gene

mRNA/cDNA for MIR1178 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1178 Gene

No ASD Table

Relevant External Links for MIR1178 Gene

GeneLoc Exon Structure for
MIR1178
ECgene alternative splicing isoforms for
MIR1178

Expression for MIR1178 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1178 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1178 Gene:

MIR1178
genes like me logo Genes that share expression patterns with MIR1178: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1178 Gene

Orthologs for MIR1178 Gene

Evolution for MIR1178 Gene

ENSEMBL:
Gene Tree for MIR1178 (if available)
TreeFam:
Gene Tree for MIR1178 (if available)

No data available for Orthologs for MIR1178 Gene

Paralogs for MIR1178 Gene

No data available for Paralogs for MIR1178 Gene

Variants for MIR1178 Gene

Sequence variations from dbSNP and Humsavar for MIR1178 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1002018596 -- 119,714,987(+) TTGAA(C/T)TGCAG intron-variant, upstream-variant-2KB
rs1002160952 -- 119,713,840(+) AAGTG(C/T)TCTTG intron-variant, upstream-variant-2KB
rs1002856443 -- 119,714,911(+) CAACT(A/G)CAAAG intron-variant, upstream-variant-2KB
rs1004466688 -- 119,713,781(+) GTAGT(C/G)TCCTG intron-variant, upstream-variant-2KB
rs1006112272 -- 119,713,555(+) GGCAG(A/G)AGGCC downstream-variant-500B, reference, missense

Relevant External Links for MIR1178 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1178

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1178 Gene

Disorders for MIR1178 Gene

Relevant External Links for MIR1178

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1178

No disorders were found for MIR1178 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1178 Gene

Publications for MIR1178 Gene

  1. MiR-1178 promotes the proliferation, G1/S transition, migration and invasion of pancreatic cancer cells by targeting CHIP. (PMID: 25635996) Cao Z. … Zhao Y. (PLoS ONE 2015) 3 64
  2. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S. … van de Rijn M. (Oncogene 2008) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1178 Gene

Sources for MIR1178 Gene

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