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Aliases for MIR10B Gene

Subcategory (RNA class) for MIR10B Gene


Quality Score for this RNA gene is


Aliases for MIR10B Gene

  • MicroRNA 10b 2 3
  • MIRN10B 3 6
  • Hsa-Mir-10b 3
  • MiRNA10B 3
  • Mir-10b 3

External Ids for MIR10B Gene

ORGUL Members for MIR10B Gene

Previous HGNC Symbols for MIR10B Gene

  • MIRN10B

Previous GeneCards Identifiers for MIR10B Gene

  • GC02P176725
  • GC02P177015

Summaries for MIR10B Gene

Entrez Gene Summary for MIR10B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR10B Gene

MIR10B (MicroRNA 10b) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR10B include pancreatic ductal adenocarcinoma and esophageal cancer. Among its related pathways are Proteoglycans in cancer and MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR10B Gene

Genomics for MIR10B Gene

Genomic Location for MIR10B Gene

176,150,303 bp from pter
176,150,412 bp from pter
110 bases
Plus strand

Genomic View for MIR10B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR10B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR10B Gene

No data available for Regulatory Elements for MIR10B Gene

Proteins for MIR10B Gene

Post-translational modifications for MIR10B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR10B Gene

Domains for MIR10B Gene

Gene Families for MIR10B Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR10B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR10B Gene

Function for MIR10B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR10B Gene

Localization for MIR10B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR10B Gene

Pathways for MIR10B Gene

genes like me logo Genes that share pathways with MIR10B: view

Pathways by source for MIR10B Gene

2 KEGG pathways for MIR10B Gene

Interacting Proteins for MIR10B Gene

Gene Ontology (GO) - Biological Process for MIR10B Gene


Transcripts for MIR10B Gene

mRNA/cDNA for MIR10B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR10B Gene

No ASD Table

Relevant External Links for MIR10B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR10B Gene

mRNA expression in normal human tissues for MIR10B Gene

genes like me logo Genes that share expressions with MIR10B: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR10B Gene

Orthologs for MIR10B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR10B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-10b 36
  • 95 (a)
(Canis familiaris)
Mammalia cfa-mir-10b 36
  • 98 (a)
(Monodelphis domestica)
Mammalia mdo-mir-10b 36
  • 90 (a)
(Mus musculus)
Mammalia Mir10b 36
  • 96 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-10b 36
  • 92 (a)
(Pan troglodytes)
Mammalia ptr-mir-10b 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-10b 36
  • 92 (a)
(Anolis carolinensis)
Reptilia aca-mir-10b 36
  • 89 (a)
(Danio rerio)
Actinopterygii dre-mir-10b-1 36
  • 87 (a)
dre-mir-10b-2 36
  • 72 (a)
dre-mir-10c 36
  • 71 (a)
Species with no ortholog for MIR10B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR10B Gene

Gene Tree for MIR10B (if available)
Gene Tree for MIR10B (if available)

Paralogs for MIR10B Gene

No data available for Paralogs for MIR10B Gene

Variants for MIR10B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR10B Gene

Variant ID Type Subtype PubMed ID
dgv676n67 CNV Gain 20364138
nsv875438 CNV Loss 21882294
nsv875446 CNV Loss 21882294

Relevant External Links for MIR10B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR10B Gene

Disorders for MIR10B Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR10B Gene in MalaCards »

(3) Diseases for MIR10B Gene including...

Relevant External Links for MIR10B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with MIR10B: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR10B Gene

Publications for MIR10B Gene

  1. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. (PMID: 17898713) Ma L. … Weinberg R.A. (Nature 2007) 3 23
  2. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  3. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. MicroRNA fingerprints during human megakaryocytopoiesis. (PMID: 16549775) Garzon R. … Croce C.M. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR10B Gene

Sources for MIR10B Gene

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