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Aliases for MIR107 Gene

Subcategory (RNA class) for MIR107 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR107 Gene

  • MicroRNA 107 2 3
  • MIRN107 3 6
  • Hsa-Mir-107 3
  • MiR-107 3

External Ids for MIR107 Gene

Previous HGNC Symbols for MIR107 Gene

  • MIRN107

Previous GeneCards Identifiers for MIR107 Gene

  • GC10M091345

Summaries for MIR107 Gene

Entrez Gene Summary for MIR107 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR107 Gene

MIR107 (MicroRNA 107) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR107 Gene

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

View fRNAdb secondary structures for MIR107

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR107 Gene

Genomics for MIR107 Gene

Genomic Location for MIR107 Gene

Start:
89,592,743 bp from pter
End:
89,592,829 bp from pter
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR107 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR107 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR107 Gene

ORGUL Member Location for MIR107 Gene

ORGUL Member Location for MIR107 gene

No data available for Regulatory Elements for MIR107 Gene

Proteins for MIR107 Gene

Post-translational modifications for MIR107 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR107 Gene

Domains for MIR107 Gene

Gene Families for MIR107 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR107: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR107 Gene

Function for MIR107 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR107 Gene

Localization for MIR107 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR107 Gene

Pathways for MIR107 Gene

SuperPathways for MIR107 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR107: view

Pathways by source for MIR107 Gene

1 KEGG pathway for MIR107 Gene

Interacting Proteins for MIR107 Gene

Gene Ontology (GO) - Biological Process for MIR107 Gene

None

Transcripts for MIR107 Gene

fRNAdb Secondary structures for MIR107 Gene

  • hsa-miR-107_MIMAT0000104_Homo_sapiens_miR-107_mature

mRNA/cDNA for MIR107 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR107 Gene

No ASD Table

Relevant External Links for MIR107 Gene

GeneLoc Exon Structure for
MIR107
ECgene alternative splicing isoforms for
MIR107

Expression for MIR107 Gene

mRNA expression in normal human tissues for MIR107 Gene

genes like me logo Genes that share expressions with MIR107: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR107 Gene

Orthologs for MIR107 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR107 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-107 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-107 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-107 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir107 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-107 36
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-107 36
  • 94 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-107 36
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-107 36
  • 100 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-107a 36
  • 85 (a)
OneToMany
dre-mir-107b 36
  • 77 (a)
OneToMany
Species with no ortholog for MIR107:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR107 Gene

ENSEMBL:
Gene Tree for MIR107 (if available)
TreeFam:
Gene Tree for MIR107 (if available)

Paralogs for MIR107 Gene

No data available for Paralogs for MIR107 Gene

Variants for MIR107 Gene

Relevant External Links for MIR107 Gene

HapMap Linkage Disequilibrium report
MIR107

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR107 Gene

Disorders for MIR107 Gene

Relevant External Links for MIR107

Human Genome Epidemiology (HuGE) Navigator
MIR107
genes like me logo Genes that share disorders with MIR107: view

No data available for UniProtKB/Swiss-Prot for MIR107 Gene

Publications for MIR107 Gene

  1. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. (PMID: 11914277) Mourelatos Z. … Dreyfuss G. (Genes Dev. 2002) 3
  2. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. (PMID: 18234899) Wang W.X. … Nelson P.T. (J. Neurosci. 2008) 3

Products for MIR107 Gene

Sources for MIR107 Gene

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