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Aliases for MIR106A Gene

Subcategory (RNA class) for MIR106A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR106A Gene

  • MicroRNA 106a 2 3 5
  • Hsa-Mir-106a 3
  • Mir-106a 3
  • MIRN106A 3
  • Mir-106 3

External Ids for MIR106A Gene

Previous HGNC Symbols for MIR106A Gene

  • MIRN106A

Previous GeneCards Identifiers for MIR106A Gene

  • GC0XM133154
  • GC0XM133155
  • GC0XM133308
  • GC0XM133309
  • GC0XM133313
  • GC0XM133317
  • GC0XM133321
  • GC0XM133326
  • GC0XM133330
  • GC0XM133334
  • GC0XM133339
  • GC0XM133350
  • GC0XM133374
  • GC0XM134175
  • GC0XM134180
  • GC0XM134186
  • GC0XM134192

Summaries for MIR106A Gene

Entrez Gene Summary for MIR106A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR106A Gene

MIR106A (MicroRNA 106a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway.

Additional gene information for MIR106A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR106A Gene

Genomics for MIR106A Gene

Regulatory Elements for MIR106A Gene

Enhancers for MIR106A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH134171 1.4 FANTOM5 ENCODE dbSUPER 0.7 -3.4 -3357 4 MXI1 ZNF76 MAX ZIC2 ETS1 ZFHX2 GLIS2 PATZ1 ZNF143 PRDM10 CCDC160 GPC3 PHF6 MIR106A GC0XM134212 GC0XM134207 ENSG00000283638
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR106A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR106A Gene

Chromosome:
X
Start:
134,170,198 bp from pter
End:
134,170,278 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR106A Gene

Genes around MIR106A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR106A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR106A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR106A Gene

Proteins for MIR106A Gene

Post-translational modifications for MIR106A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR106A Gene

Domains & Families for MIR106A Gene

Gene Families for MIR106A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR106A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR106A Gene

Function for MIR106A Gene

Phenotypes From GWAS Catalog for MIR106A Gene

Gene Ontology (GO) - Molecular Function for MIR106A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20190813
genes like me logo Genes that share ontologies with MIR106A: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR106A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR106A Gene

Localization for MIR106A Gene

Gene Ontology (GO) - Cellular Components for MIR106A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR106A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR106A Gene

Pathways & Interactions for MIR106A Gene

SuperPathways for MIR106A Gene

SuperPathway Contained pathways
1 Parkinsons Disease Pathway
genes like me logo Genes that share pathways with MIR106A: view

Pathways by source for MIR106A Gene

1 BioSystems pathway for MIR106A Gene

Interacting Proteins for MIR106A Gene

Gene Ontology (GO) - Biological Process for MIR106A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 20190813
genes like me logo Genes that share ontologies with MIR106A: view

No data available for SIGNOR curated interactions for MIR106A Gene

Drugs & Compounds for MIR106A Gene

No Compound Related Data Available

Transcripts for MIR106A Gene

mRNA/cDNA for MIR106A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR106A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR106A Gene

No ASD Table

Relevant External Links for MIR106A Gene

GeneLoc Exon Structure for
MIR106A
ECgene alternative splicing isoforms for
MIR106A

Expression for MIR106A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR106A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR106A Gene:

MIR106A
genes like me logo Genes that share expression patterns with MIR106A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR106A Gene

Orthologs for MIR106A Gene

Evolution for MIR106A Gene

ENSEMBL:
Gene Tree for MIR106A (if available)
TreeFam:
Gene Tree for MIR106A (if available)

No data available for Orthologs for MIR106A Gene

Paralogs for MIR106A Gene

No data available for Paralogs for MIR106A Gene

Variants for MIR106A Gene

Sequence variations from dbSNP and Humsavar for MIR106A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000692193 -- 134,172,082(+) CCCCT(C/T)CCACC upstream-variant-2KB
rs1003822325 -- 134,171,007(+) AAACC(C/T)TCTCC upstream-variant-2KB
rs1004871742 -- 134,171,563(+) CCTTA(A/G)ATTGC upstream-variant-2KB
rs1004902717 -- 134,170,953(+) ACCAA(A/G)GTAGG upstream-variant-2KB
rs1005828091 -- 134,169,983(+) ATGTG(G/T)CCTAT downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR106A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR106A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR106A Gene

Disorders for MIR106A Gene

Relevant External Links for MIR106A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR106A

No disorders were found for MIR106A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR106A Gene

Publications for MIR106A Gene

  1. Functional analysis of serum microRNAs miR-21 and miR-106a in renal cell carcinoma. (PMID: 27814278) Tusong H … Wang YJ (Cancer biomarkers : section A of Disease markers 2017) 3 60
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  3. MiR-106a: Promising biomarker for cancer. (PMID: 27780637) Pan YJ … Pei DS (Bioorganic & medicinal chemistry letters 2016) 3 60
  4. Up-regulated Circulating miR-106a by DNA Methylation Promised a Potential Diagnostic and Prognostic Marker for Gastric Cancer. (PMID: 26179261) Yuan R … Xue X (Anti-cancer agents in medicinal chemistry 2016) 3 60
  5. miR-106a promotes cardiac hypertrophy by targeting mitofusin 2. (PMID: 27565029) Guan X … Xu C (Journal of molecular and cellular cardiology 2016) 3 60

Products for MIR106A Gene

Sources for MIR106A Gene

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