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Aliases for MIR106A Gene

Subcategory (RNA class) for MIR106A Gene


Quality Score for this RNA gene is


Aliases for MIR106A Gene

  • MicroRNA 106a 2 3 5
  • Hsa-Mir-106a 3
  • Mir-106a 3
  • MIRN106A 3
  • Mir-106 3

External Ids for MIR106A Gene

Previous HGNC Symbols for MIR106A Gene

  • MIRN106A

Previous GeneCards Identifiers for MIR106A Gene

  • GC0XM133154
  • GC0XM133155
  • GC0XM133308
  • GC0XM133309
  • GC0XM133313
  • GC0XM133317
  • GC0XM133321
  • GC0XM133326
  • GC0XM133330
  • GC0XM133334
  • GC0XM133339
  • GC0XM133350
  • GC0XM133374
  • GC0XM134175
  • GC0XM134180

Summaries for MIR106A Gene

Entrez Gene Summary for MIR106A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR106A Gene

MIR106A (MicroRNA 106a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR106A Gene

Genomics for MIR106A Gene

Regulatory Elements for MIR106A Gene

Enhancers for MIR106A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR106A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR106A Gene

134,170,198 bp from pter
134,170,278 bp from pter
81 bases
Minus strand

Genomic View for MIR106A Gene

Genes around MIR106A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR106A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR106A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR106A Gene

Proteins for MIR106A Gene

Post-translational modifications for MIR106A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR106A Gene

Domains & Families for MIR106A Gene

Gene Families for MIR106A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR106A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR106A Gene

Function for MIR106A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR106A Gene

Localization for MIR106A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR106A Gene

Pathways & Interactions for MIR106A Gene

SuperPathways for MIR106A Gene

No Data Available

Interacting Proteins for MIR106A Gene

Gene Ontology (GO) - Biological Process for MIR106A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR106A Gene

Drugs & Compounds for MIR106A Gene

No Compound Related Data Available

Transcripts for MIR106A Gene

mRNA/cDNA for MIR106A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR106A Gene

No ASD Table

Relevant External Links for MIR106A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR106A Gene

mRNA expression in normal human tissues for MIR106A Gene

genes like me logo Genes that share expression patterns with MIR106A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR106A Gene

Orthologs for MIR106A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR106A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-106a 36
  • 99 (a)
(Canis familiaris)
Mammalia cfa-mir-106a 36
  • 93 (a)
(Monodelphis domestica)
Mammalia mdo-mir-17 36
  • 69 (a)
(Mus musculus)
Mammalia Mir106a 36
  • 91 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-106 36
  • 62 (a)
(Pan troglodytes)
Mammalia ptr-mir-106a 36
  • 99 (a)
(Gallus gallus)
Aves gga-mir-106 36
  • 75 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 76 (a)
(Danio rerio)
Actinopterygii dre-mir-17a-1 36
  • 43 (a)
Species with no ortholog for MIR106A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR106A Gene

Gene Tree for MIR106A (if available)
Gene Tree for MIR106A (if available)

Paralogs for MIR106A Gene

No data available for Paralogs for MIR106A Gene

Variants for MIR106A Gene

Sequence variations from dbSNP and Humsavar for MIR106A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs749413699 -- 134,172,188(+) CGGCC(C/T)GCCCC upstream-variant-2KB
rs750729298 -- 134,172,123(+) CCCCA(A/G)CGAAG upstream-variant-2KB
rs377321718 -- 134,172,141(+) TTCTT(A/G)CCCAG upstream-variant-2KB
rs780538372 -- 134,172,152(+) CCACC(C/G)GCTCG upstream-variant-2KB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR106A Gene

Disorders for MIR106A Gene

Relevant External Links for MIR106A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR106A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR106A Gene

Publications for MIR106A Gene

  1. miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction. (PMID: 25531890) Imig J. … Hall J. (Nat. Chem. Biol. 2015) 3 67
  2. Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2. (PMID: 24704830) Wang Z. … Bian X.W. (Oncogene 2015) 3
  3. MicroRNA-106a confers cisplatin resistance in non-small cell lung cancer A549 cells by targeting adenosine triphosphatase-binding cassette A1. (PMID: 25339370) Ma Y. … Li Y. (Mol Med Rep 2015) 3
  4. Upregulated expression of miR-106a by DNA hypomethylation plays an oncogenic role in hepatocellular carcinoma. (PMID: 25510666) Yuan R. … Hu H. (Tumour Biol. 2015) 3
  5. The PDGF-D/miR-106a/Twist1 pathway orchestrates epithelial-mesenchymal transition in gemcitabine resistance hepatoma cells. (PMID: 25760076) Wang R. … Wu Q. (Oncotarget 2015) 3

Products for MIR106A Gene

Sources for MIR106A Gene