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Aliases for MIR106A Gene

Subcategory (RNA class) for MIR106A Gene


Quality Score for this RNA gene is


Aliases for MIR106A Gene

  • MicroRNA 106a 2 3
  • MicroRNA 19b-2 5
  • Hsa-Mir-106a 3
  • Mir-106a 3
  • MIRN106A 3
  • Mir-106 3
  • MIR19B2 5

External Ids for MIR106A Gene

Previous HGNC Symbols for MIR106A Gene

  • MIRN106A

Previous GeneCards Identifiers for MIR106A Gene

  • GC0XM133154
  • GC0XM133155
  • GC0XM133308
  • GC0XM133309
  • GC0XM133313
  • GC0XM133317
  • GC0XM133321
  • GC0XM133326
  • GC0XM133330
  • GC0XM133334
  • GC0XM133339
  • GC0XM133350
  • GC0XM133374
  • GC0XM134175
  • GC0XM134180

Summaries for MIR106A Gene

Entrez Gene Summary for MIR106A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR106A Gene

MIR106A (MicroRNA 106a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR106A Gene

Genomics for MIR106A Gene

Regulatory Elements for MIR106A Gene

Enhancers for MIR106A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF134171 1.4 FANTOM5 Ensembl ENCODE 0.8 +0.5 455 4.8 MAX ZNF76 ZIC2 ZNF664 ZFHX2 GLIS2 POLR2A PATZ1 ZNF143 PRDM10 CCDC160 GPC3 PHF6 GC0XM134196 GC0XM134201 MIR106A MIR19B2 MIR20B MIR363 MIR92A2
GH0XF134179 0.4 ENCODE 0.4 -6.9 -6879 2.4 ZNF133 MIR106A MIR20B MIR92A2 MIR363 MIR19B2 MIR18B LARP1BP3
GH0XF134187 0.4 Ensembl 0.4 -13.2 -13212 0.2 CBX8 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134186 0.4 ENCODE 0.4 -12.9 -12857 0.2 CBX8 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134188 0.2 Ensembl 0.4 -12.4 -12412 0.2 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR106A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR106A Gene

134,168,911 bp from pter
134,174,089 bp from pter
5,179 bases
Minus strand

Genomic View for MIR106A Gene

Genes around MIR106A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR106A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR106A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR106A Gene

Proteins for MIR106A Gene

Post-translational modifications for MIR106A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR106A Gene

Domains & Families for MIR106A Gene

Gene Families for MIR106A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR106A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR106A Gene

Function for MIR106A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR106A Gene

Localization for MIR106A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR106A Gene

Pathways & Interactions for MIR106A Gene

SuperPathways for MIR106A Gene

SuperPathway Contained pathways
1 Parkinsons Disease Pathway
genes like me logo Genes that share pathways with MIR106A: view

Pathways by source for MIR106A Gene

1 BioSystems pathway for MIR106A Gene

Interacting Proteins for MIR106A Gene

Gene Ontology (GO) - Biological Process for MIR106A Gene


No data available for SIGNOR curated interactions for MIR106A Gene

Transcripts for MIR106A Gene

mRNA/cDNA for MIR106A Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR106A Gene

No ASD Table

Relevant External Links for MIR106A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR106A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR106A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR106A Gene:

genes like me logo Genes that share expression patterns with MIR106A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR106A Gene

Orthologs for MIR106A Gene

Evolution for MIR106A Gene

Gene Tree for MIR106A (if available)
Gene Tree for MIR106A (if available)

No data available for Orthologs for MIR106A Gene

Paralogs for MIR106A Gene

No data available for Paralogs for MIR106A Gene

Variants for MIR106A Gene

Sequence variations from dbSNP and Humsavar for MIR106A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs113658998 -- 134,170,166(+) CACAA(A/G)CTACA downstream-variant-500B, upstream-variant-2KB
rs137881717 -- 134,171,170(+) TAAAC(A/G)AGTGA upstream-variant-2KB
rs142112727 -- 134,171,521(+) TCTGG(C/T)ATCCC upstream-variant-2KB
rs146939378 -- 134,170,567(+) TATGT(A/C)TAAGC upstream-variant-2KB
rs180944931 -- 134,170,957(+) AAGTA(A/G)GCAGA upstream-variant-2KB

Relevant External Links for MIR106A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR106A Gene

Disorders for MIR106A Gene

Relevant External Links for MIR106A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR106A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR106A Gene

Publications for MIR106A Gene

  1. Micro RNAs mir-106a, mir-122 and mir-197 are increased in severe acute viral hepatitis with coagulopathy. (PMID: 26352910) Weseslindtner L. … Odenthal M. (Liver Int. 2016) 3 64
  2. Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2. (PMID: 24704830) Wang Z. … Bian X.W. (Oncogene 2015) 3 64
  3. MicroRNA-106a confers cisplatin resistance in non-small cell lung cancer A549 cells by targeting adenosine triphosphatase-binding cassette A1. (PMID: 25339370) Ma Y. … Li Y. (Mol Med Rep 2015) 3 64
  4. miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction. (PMID: 25531890) Imig J. … Hall J. (Nat. Chem. Biol. 2015) 3 64
  5. The Effects and Molecular Mechanisms of MiR-106a in Multidrug Resistance Reversal in Human Glioma U87/DDP and U251/G Cell Lines. (PMID: 25950430) Wang Q. … Yang P. (PLoS ONE 2015) 3 64

Products for MIR106A Gene

Sources for MIR106A Gene

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