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Aliases for MIR103B2 Gene

Subcategory (RNA class) for MIR103B2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR103B2 Gene

  • MicroRNA 103b-2 2 3 5
  • MicroRNA 103-2-As 2 3
  • Hsa-Mir-103-2-As 3
  • Hsa-Mir-103b-2 3
  • MIR103-2-AS 3
  • MIRN103-2AS 3
  • MIR103-2AS 3

External Ids for MIR103B2 Gene

Previous HGNC Symbols for MIR103B2 Gene

  • MIRN103-2AS
  • MIR103-2AS

Summaries for MIR103B2 Gene

Entrez Gene Summary for MIR103B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR103B2 Gene

MIR103B2 (MicroRNA 103b-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

Additional gene information for MIR103B2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR103B2 Gene

Genomics for MIR103B2 Gene

Genomic Location for MIR103B2 Gene

Chromosome:
20
Start:
3,917,502 bp from pter
End:
3,917,563 bp from pter
Size:
62 bases
Orientation:
Minus strand

Genomic View for MIR103B2 Gene

Genes around MIR103B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR103B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR103B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR103B2 Gene

ORGUL Member Location for MIR103B2 Gene

ORGUL Member Location for MIR103B2 gene

No data available for Regulatory Elements for MIR103B2 Gene

Proteins for MIR103B2 Gene

Post-translational modifications for MIR103B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR103B2 Gene

Domains & Families for MIR103B2 Gene

Gene Families for MIR103B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR103B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR103B2 Gene

Function for MIR103B2 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR103B2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR103B2 Gene

Localization for MIR103B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR103B2 Gene

Pathways & Interactions for MIR103B2 Gene

SuperPathways for MIR103B2 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR103B2: view

Pathways by source for MIR103B2 Gene

1 KEGG pathway for MIR103B2 Gene

Interacting Proteins for MIR103B2 Gene

Gene Ontology (GO) - Biological Process for MIR103B2 Gene

None

No data available for SIGNOR curated interactions for MIR103B2 Gene

Drugs & Compounds for MIR103B2 Gene

No Compound Related Data Available

Transcripts for MIR103B2 Gene

mRNA/cDNA for MIR103B2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR103B2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR103B2 Gene

No ASD Table

Relevant External Links for MIR103B2 Gene

GeneLoc Exon Structure for
MIR103B2
ECgene alternative splicing isoforms for
MIR103B2

Expression for MIR103B2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR103B2 Gene:

MIR103B2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR103B2 Gene

Orthologs for MIR103B2 Gene

Evolution for MIR103B2 Gene

ENSEMBL:
Gene Tree for MIR103B2 (if available)
TreeFam:
Gene Tree for MIR103B2 (if available)

No data available for Orthologs for MIR103B2 Gene

Paralogs for MIR103B2 Gene

No data available for Paralogs for MIR103B2 Gene

Variants for MIR103B2 Gene

Sequence variations from dbSNP and Humsavar for MIR103B2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs137852959 Pathogenic 3,918,695(+) TTGTT(A/G)GAAAT nc-transcript-variant, upstream-variant-2KB, reference, missense
rs137852967 Pathogenic 3,918,717(+) TAATA(C/T)GATCG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs1000759813 -- 3,917,095(+) TACTG(A/C)ACTTA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001357613 -- 3,918,656(+) CCTTT(C/T)TTTGG intron-variant, upstream-variant-2KB
rs1003890203 -- 3,917,652(+) TTGTT(A/T)AATTA intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR103B2 Gene

Variant ID Type Subtype PubMed ID
esv3645053 CNV loss 21293372
esv3645054 CNV gain 21293372
nsv828673 CNV gain 20364138

Relevant External Links for MIR103B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR103B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR103B2 Gene

Disorders for MIR103B2 Gene

Relevant External Links for MIR103B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR103B2

No disorders were found for MIR103B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR103B2 Gene

Publications for MIR103B2 Gene

  1. miRNA-103: molecular link between insulin resistance and nonalcoholic fatty liver disease. (PMID: 25593466) Xu Q … Yao MX (World journal of gastroenterology 2015) 3 60
  2. MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN. (PMID: 24828205) Geng L … Fang XD (International journal of molecular sciences 2014) 3 60
  3. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A … Siomi MC (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR103B2 Gene

Sources for MIR103B2 Gene

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